Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006209                                                              20     390
XP_006713721                                                           20     390
XP_005250923                                                           17    2528
NP_055194                                                              17    2528
NP_001188413                                                           17    4312
NP_116023                                                              17    4312
NP_690577                                                              17    4312
NP_001170991                                                           17    4312
NP_001120973                                                           17    4312
NP_000469                                                              17    4312
NP_004652                                                              17    4312
NP_061763                                                              17    4312
XP_005251676                                                           17    4312
XP_005245877                                                           17    4312
XP_005245875                                                           17    4312
XP_006710609                                                           17    4312
NP_690610                                                              16    5631
NP_000034                                                              16    5631
NP_001008225                                                           16    5631
NP_060473                                                              16    5631
NP_079511                                                              16    5631
NP_071365                                                              16    5631
XP_005260285                                                           16    5631
XP_006723916                                                           16    5631
XP_005254586                                                           16    5631
XP_005254585                                                           16    5631
XP_005254584                                                           16    5631
XP_005270242                                                           16    5631
XP_006717882                                                           16    5631
NP_001786                                                              16    7355
NP_005752                                                              16    7355
NP_001269836                                                           16    7355
NP_001269837                                                           16    7355
NP_001269838                                                           16    7355
NP_006576                                                              16    7355
XP_006719249                                                           16    7355
NP_001122107                                                           16    7355
NP_001122105                                                           16    7355
NP_056487                                                              16    7355
NP_006205                                                              15    9605
NP_060145                                                              15    9605
NP_001032626                                                           15    9605
NP_005236                                                              15    9605
NP_001611                                                              15    9605
NP_775764                                                              15    9605
NP_001165447                                                           15    9605
NP_001243465                                                           15    9605
NP_620137                                                              15    9605
NP_006648                                                              15    9605
NP_001008781                                                           15    9605
NP_062828                                                              15    9605
NP_996848                                                              15    9605
NP_001139504                                                           15    9605
NP_003153                                                              15    9605
XP_006724025                                                           15    9605
XP_006724024                                                           15    9605
XP_006724023                                                           15    9605
XP_005267366                                                           15    9605
XP_006720083                                                           15    9605
XP_006720082                                                           15    9605
XP_006719049                                                           15    9605
XP_006718827                                                           15    9605
XP_006718749                                                           15    9605
XP_005274302                                                           15    9605
XP_005274301                                                           15    9605
XP_005274300                                                           15    9605
XP_005274299                                                           15    9605
XP_005274298                                                           15    9605
XP_005274297                                                           15    9605
XP_005252526                                                           15    9605
XP_006714950                                                           15    9605
XP_006714202                                                           15    9605
XP_005262892                                                           15    9605
XP_005262891                                                           15    9605
XP_005264576                                                           15    9605
NP_694591                                                              15    9605
>NP_006209
          Length = 1068

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VSVNIRDID 9
           V+VNIRDID
Sbjct: 344 VNVNIRDID 352
>XP_006713721
          Length = 1068

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VSVNIRDID 9
           V+VNIRDID
Sbjct: 344 VNVNIRDID 352
>XP_005250923
          Length = 500

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSVNIRDI 8
           +SVN+RD+
Sbjct: 464 ISVNLRDV 471
>NP_055194
          Length = 500

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSVNIRDI 8
           +SVN+RD+
Sbjct: 464 ISVNLRDV 471
>NP_001188413
          Length = 672

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SVNIRDID 9
           S N+RD+D
Sbjct: 198 SFNVRDLD 205
>NP_116023
          Length = 1089

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SVNIRDID 9
           S N+RD+D
Sbjct: 198 SFNVRDLD 205
>NP_690577
          Length = 672

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SVNIRDID 9
           S N+RD+D
Sbjct: 198 SFNVRDLD 205
>NP_001170991
          Length = 447

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NIRDID 9
           NIRDID
Sbjct: 134 NIRDID 139
>NP_001120973
          Length = 469

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NIRDID 9
           NIRDID
Sbjct: 156 NIRDID 161
>NP_000469
          Length = 524

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NIRDID 9
           NIRDID
Sbjct: 211 NIRDID 216
>NP_004652
          Length = 597

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NIRDID 9
           NIRDID
Sbjct: 275 NIRDID 280
>NP_061763
          Length = 793

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSVNIRDID 9
           VSV+ RD+D
Sbjct: 262 VSVSARDLD 270
>XP_005251676
          Length = 1089

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SVNIRDID 9
           S N+RD+D
Sbjct: 198 SFNVRDLD 205
>XP_005245877
          Length = 390

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NIRDID 9
           NIRDID
Sbjct: 211 NIRDID 216
>XP_005245875
          Length = 524

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NIRDID 9
           NIRDID
Sbjct: 211 NIRDID 216
>XP_006710609
          Length = 524

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   NIRDID 9
           NIRDID
Sbjct: 211 NIRDID 216
>NP_690610
          Length = 314

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VSVNIRDID 9
           V++N+ D+D
Sbjct: 199 VAINLSDVD 207
>NP_000034
          Length = 335

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VSVNIRDID 9
           V++N+ D+D
Sbjct: 220 VAINLSDVD 228
>NP_001008225
          Length = 1403

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SVNIRDID 9
           SVN +D+D
Sbjct: 146 SVNAKDVD 153
>NP_060473
          Length = 1416

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SVNIRDID 9
           SVN +D+D
Sbjct: 159 SVNAKDVD 166
>NP_079511
          Length = 1166

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SVNIRDID 9
           SVN RDI+
Sbjct: 516 SVNCRDIE 523
>NP_071365
          Length = 436

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSVNIRDI 8
           +SVNI+D+
Sbjct: 356 ISVNIQDL 363
>XP_005260285
          Length = 430

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSVNIRDI 8
           +SVNI+D+
Sbjct: 350 ISVNIQDL 357
>XP_006723916
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSVNIRDI 8
           +SVNI+D+
Sbjct: 376 ISVNIQDL 383
>XP_005254586
          Length = 1392

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SVNIRDID 9
           SVN +D+D
Sbjct: 146 SVNAKDVD 153
>XP_005254585
          Length = 1405

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SVNIRDID 9
           SVN +D+D
Sbjct: 159 SVNAKDVD 166
>XP_005254584
          Length = 1411

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SVNIRDID 9
           SVN +D+D
Sbjct: 154 SVNAKDVD 161
>XP_005270242
          Length = 734

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SVNIRDID 9
          SVN RDI+
Sbjct: 84 SVNCRDIE 91
>XP_006717882
          Length = 362

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VSVNIRDID 9
           V++N+ D+D
Sbjct: 247 VAINLSDVD 255
>NP_001786
          Length = 784

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VSVNIRDID 9
           V +NI D+D
Sbjct: 359 VIINITDVD 367
>NP_005752
          Length = 1568

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VSVNIRDID 9
            +SVN+ D D
Sbjct: 1220 ISVNVLDCD 1228
>NP_001269836
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NIRDID 9
           N+RDID
Sbjct: 134 NLRDID 139
>NP_001269837
          Length = 497

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NIRDID 9
           N+RDID
Sbjct: 102 NLRDID 107
>NP_001269838
          Length = 475

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NIRDID 9
          N+RDID
Sbjct: 80 NLRDID 85
>NP_006576
          Length = 548

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NIRDID 9
           N+RDID
Sbjct: 153 NLRDID 158
>XP_006719249
          Length = 1555

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VSVNIRDID 9
            +SVN+ D D
Sbjct: 1207 ISVNVLDCD 1215
>NP_001122107
          Length = 1639

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   VNIRDID 9
           +N+RD+D
Sbjct: 520 LNVRDLD 526
>NP_001122105
          Length = 1639

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   VNIRDID 9
           +N+RD+D
Sbjct: 520 LNVRDLD 526
>NP_056487
          Length = 1639

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   VNIRDID 9
           +N+RD+D
Sbjct: 520 LNVRDLD 526
>NP_006205
          Length = 338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SVNIRDI 8
           SVN++DI
Sbjct: 317 SVNLKDI 323
>NP_060145
          Length = 1310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VSVNIRDID 9
           V VN++D++
Sbjct: 794 VCVNVKDVN 802
>NP_001032626
          Length = 238

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SVNIRDI 8
           SVN++DI
Sbjct: 217 SVNLKDI 223
>NP_005236
          Length = 4588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VSVNIRDID 9
            V+VN+ DI+
Sbjct: 3321 VNVNVTDIN 3329
>NP_001611
          Length = 5890

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VSVNIRDID 9
            + VN+ DID
Sbjct: 1620 MDVNVGDID 1628
>NP_775764
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   VNIRDI 8
           VN+RDI
Sbjct: 132 VNVRDI 137
>NP_001165447
          Length = 1310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VSVNIRDID 9
           V VN++D++
Sbjct: 794 VCVNVKDVN 802
>NP_001243465
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   NIRDID 9
           N+RD+D
Sbjct: 357 NVRDLD 362
>NP_620137
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SVNIRDID 9
           S+NI D+D
Sbjct: 312 SLNIPDVD 319
>NP_006648
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSVNIRDI 8
           V +N+RDI
Sbjct: 498 VLINLRDI 505
>NP_001008781
          Length = 4557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VSVNIRDID 9
            V VNI DI+
Sbjct: 2070 VRVNIEDIN 2078
>NP_062828
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   NIRDID 9
           N+RD+D
Sbjct: 366 NVRDLD 371
>NP_996848
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSVNIRDI 8
           V +N+RDI
Sbjct: 498 VLINLRDI 505
>NP_001139504
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SVNIRDID 9
           S+NI D+D
Sbjct: 279 SLNIPDVD 286
>NP_003153
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   NIRDID 9
           N+RD+D
Sbjct: 360 NLRDVD 365
>XP_006724025
          Length = 635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSVNIRDI 8
           V +N+RDI
Sbjct: 541 VLINLRDI 548
>XP_006724024
          Length = 584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSVNIRDI 8
           V +N+RDI
Sbjct: 541 VLINLRDI 548
>XP_006724023
          Length = 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSVNIRDI 8
           V +N+RDI
Sbjct: 498 VLINLRDI 505
>XP_005267366
          Length = 1330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    SVNIRDI 8
            ++NIRD+
Sbjct: 1071 AINIRDV 1077
>XP_006720083
          Length = 1355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    SVNIRDI 8
            ++NIRD+
Sbjct: 1044 AINIRDV 1050
>XP_006720082
          Length = 1363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    SVNIRDI 8
            ++NIRD+
Sbjct: 1071 AINIRDV 1077
>XP_006719049
          Length = 257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   NIRDID 9
           N+RD+D
Sbjct: 229 NVRDLD 234
>XP_006718827
          Length = 3479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VSVNIRDID 9
           V VNI DI+
Sbjct: 960 VRVNIEDIN 968
>XP_006718749
          Length = 4596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VSVNIRDID 9
            + VN+ DID
Sbjct: 1620 MDVNVGDID 1628
>XP_005274302
          Length = 5438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VSVNIRDID 9
            + VN+ DID
Sbjct: 1620 MDVNVGDID 1628
>XP_005274301
          Length = 5762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VSVNIRDID 9
            + VN+ DID
Sbjct: 1620 MDVNVGDID 1628
>XP_005274300
          Length = 5762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VSVNIRDID 9
            + VN+ DID
Sbjct: 1620 MDVNVGDID 1628
>XP_005274299
          Length = 5762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VSVNIRDID 9
            + VN+ DID
Sbjct: 1492 MDVNVGDID 1500
>XP_005274298
          Length = 5890

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VSVNIRDID 9
            + VN+ DID
Sbjct: 1620 MDVNVGDID 1628
>XP_005274297
          Length = 5890

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VSVNIRDID 9
            + VN+ DID
Sbjct: 1620 MDVNVGDID 1628
>XP_005252526
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SVNIRDI 8
           SVN++DI
Sbjct: 244 SVNLKDI 250
>XP_006714950
          Length = 1304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VSVNIRDID 9
           V VN++D++
Sbjct: 794 VCVNVKDVN 802
>XP_006714202
          Length = 4588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VSVNIRDID 9
            V+VN+ DI+
Sbjct: 3321 VNVNVTDIN 3329
>XP_005262892
          Length = 4600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VSVNIRDID 9
            V+VN+ DI+
Sbjct: 3321 VNVNVTDIN 3329
>XP_005262891
          Length = 4600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VSVNIRDID 9
            V+VN+ DI+
Sbjct: 3321 VNVNVTDIN 3329
>XP_005264576
          Length = 743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   NIRDID 9
           N+RD+D
Sbjct: 323 NLRDVD 328
>NP_694591
          Length = 1382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    SVNIRDI 8
            ++NIRD+
Sbjct: 1071 AINIRDV 1077
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.322    0.143    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 400,706
Number of extensions: 638
Number of successful extensions: 76
Number of sequences better than 10000.0: 76
Number of HSP's gapped: 76
Number of HSP's successfully gapped: 76
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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