Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           20     509
NP_000242                                                              20     509
XP_005264389                                                           20     509
NP_001032752                                                           18    1482
NP_066944                                                              18    1482
NP_001950                                                              18    1482
NP_003990                                                              17    3301
NP_001161827                                                           17    3301
XP_005248444                                                           17    3301
XP_005248443                                                           17    3301
XP_005248442                                                           17    3301
XP_005248441                                                           17    3301
NP_997064                                                              17    4312
NP_000263                                                              17    4312
XP_006712615                                                           17    4312
XP_005263735                                                           17    4312
XP_005263732                                                           17    4312
XP_006712614                                                           17    4312
NP_203752                                                              16    5631
NP_001139381                                                           16    5631
NP_891549                                                              16    5631
XP_006712875                                                           16    5631
XP_006712874                                                           16    5631
XP_006712873                                                           16    5631
XP_006712872                                                           16    5631
XP_005246976                                                           16    5631
XP_005246975                                                           16    5631
NP_001268917                                                           16    7355
NP_001268916                                                           16    7355
NP_066976                                                              16    7355
NP_001123361                                                           16    7355
NP_001913                                                              16    7355
NP_653170                                                              16    7355
XP_006722504                                                           16    7355
XP_006722503                                                           16    7355
XP_005245068                                                           16    7355
XP_005245067                                                           16    7355
XP_006711094                                                           16    7355
XP_006711093                                                           16    7355
XP_006711092                                                           16    7355
XP_006711091                                                           16    7355
NP_055964                                                              16    7355
NP_001078855                                                           16    7355
NP_997400                                                              15    9605
NP_001026                                                              15    9605
NP_003961                                                              15    9605
NP_002827                                                              15    9605
NP_543031                                                              15    9605
NP_543030                                                              15    9605
NP_001034678                                                           15    9605
NP_001375                                                              15    9605
NP_663780                                                              15    9605
NP_001257957                                                           15    9605
NP_777562                                                              15    9605
NP_056356                                                              15    9605
NP_981947                                                              15    9605
XP_005266741                                                           15    9605
XP_005266739                                                           15    9605
XP_005272494                                                           15    9605
XP_005272493                                                           15    9605
XP_005272492                                                           15    9605
XP_006716300                                                           15    9605
XP_006711873                                                           15    9605
XP_006711872                                                           15    9605
XP_006711871                                                           15    9605
XP_006711870                                                           15    9605
XP_006711869                                                           15    9605
XP_006711868                                                           15    9605
XP_006711867                                                           15    9605
XP_006711866                                                           15    9605
XP_006711865                                                           15    9605
NP_114097                                                              15    9605
>NP_001245210
          Length = 868

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SVEDTTGS 9
           SVEDTTGS
Sbjct: 250 SVEDTTGS 257
>NP_000242
          Length = 934

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SVEDTTGS 9
           SVEDTTGS
Sbjct: 316 SVEDTTGS 323
>XP_005264389
          Length = 921

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SVEDTTGS 9
           SVEDTTGS
Sbjct: 316 SVEDTTGS 323
>NP_001032752
          Length = 225

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  VEDTTGS 9
          VEDTTGS
Sbjct: 84 VEDTTGS 90
>NP_066944
          Length = 225

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  VEDTTGS 9
          VEDTTGS
Sbjct: 84 VEDTTGS 90
>NP_001950
          Length = 225

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  VEDTTGS 9
          VEDTTGS
Sbjct: 84 VEDTTGS 90
>NP_003990
          Length = 979

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VSVEDTTG 8
           VSV+D+TG
Sbjct: 138 VSVQDSTG 145
>NP_001161827
          Length = 342

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VSVEDTTG 8
           VSV+D+TG
Sbjct: 138 VSVQDSTG 145
>XP_005248444
          Length = 581

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VSVEDTTG 8
           VSV+D+TG
Sbjct: 138 VSVQDSTG 145
>XP_005248443
          Length = 582

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VSVEDTTG 8
           VSV+D+TG
Sbjct: 138 VSVQDSTG 145
>XP_005248442
          Length = 980

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VSVEDTTG 8
           VSV+D+TG
Sbjct: 138 VSVQDSTG 145
>XP_005248441
          Length = 980

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VSVEDTTG 8
           VSV+D+TG
Sbjct: 138 VSVQDSTG 145
>NP_997064
          Length = 732

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SVEDTTGS 9
           +VEDT GS
Sbjct: 282 TVEDTNGS 289
>NP_000263
          Length = 733

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SVEDTTGS 9
           +VEDT GS
Sbjct: 282 TVEDTNGS 289
>XP_006712615
          Length = 465

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SVEDTTGS 9
           +VEDT GS
Sbjct: 282 TVEDTNGS 289
>XP_005263735
          Length = 686

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SVEDTTGS 9
           +VEDT GS
Sbjct: 282 TVEDTNGS 289
>XP_005263732
          Length = 767

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SVEDTTGS 9
           +VEDT GS
Sbjct: 282 TVEDTNGS 289
>XP_006712614
          Length = 768

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SVEDTTGS 9
           +VEDT GS
Sbjct: 282 TVEDTNGS 289
>NP_203752
          Length = 1861

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSVEDTTGS 9
           V+ E+TTGS
Sbjct: 272 VAEEETTGS 280
>NP_001139381
          Length = 1390

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSVEDTTGS 9
           V+ E+TTGS
Sbjct: 271 VAEEETTGS 279
>NP_891549
          Length = 712

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VSVEDTT 7
           +SVEDTT
Sbjct: 336 LSVEDTT 342
>XP_006712875
          Length = 1826

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSVEDTTGS 9
           V+ E+TTGS
Sbjct: 237 VAEEETTGS 245
>XP_006712874
          Length = 1836

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSVEDTTGS 9
           V+ E+TTGS
Sbjct: 247 VAEEETTGS 255
>XP_006712873
          Length = 1861

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSVEDTTGS 9
           V+ E+TTGS
Sbjct: 272 VAEEETTGS 280
>XP_006712872
          Length = 1861

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSVEDTTGS 9
           V+ E+TTGS
Sbjct: 272 VAEEETTGS 280
>XP_005246976
          Length = 1864

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSVEDTTGS 9
           V+ E+TTGS
Sbjct: 282 VAEEETTGS 290
>XP_005246975
          Length = 1871

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSVEDTTGS 9
           V+ E+TTGS
Sbjct: 282 VAEEETTGS 290
>NP_001268917
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSVEDTTG 8
           ++ EDTTG
Sbjct: 265 IASEDTTG 272
>NP_001268916
          Length = 1203

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSVEDTTG 8
           ++ EDTTG
Sbjct: 772 IASEDTTG 779
>NP_066976
          Length = 772

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VSVEDTTGS 9
           +SVEDT  S
Sbjct: 509 LSVEDTNNS 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SVEDTTG 8
           SVE TTG
Sbjct: 198 SVEPTTG 204
>NP_001123361
          Length = 552

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSVEDTTG 8
           VSVE+T G
Sbjct: 494 VSVEETPG 501
>NP_001913
          Length = 519

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSVEDTTG 8
           VSVE+T G
Sbjct: 461 VSVEETPG 468
>NP_653170
          Length = 1216

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSVEDTTG 8
           ++ EDTTG
Sbjct: 772 IASEDTTG 779
>XP_006722504
          Length = 613

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VSVEDTTGS 9
           +SVEDT  S
Sbjct: 509 LSVEDTNNS 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SVEDTTG 8
           SVE TTG
Sbjct: 198 SVEPTTG 204
>XP_006722503
          Length = 772

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VSVEDTTGS 9
           +SVEDT  S
Sbjct: 509 LSVEDTNNS 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SVEDTTG 8
           SVE TTG
Sbjct: 198 SVEPTTG 204
>XP_005245068
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VSVEDTTGS 9
           +SVED  G+
Sbjct: 652 ISVEDNNGN 660
>XP_005245067
          Length = 768

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VSVEDTTGS 9
           +SVED  G+
Sbjct: 654 ISVEDNNGN 662
>XP_006711094
          Length = 932

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSVEDTTG 8
           ++ EDTTG
Sbjct: 501 IASEDTTG 508
>XP_006711093
          Length = 946

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSVEDTTG 8
           ++ EDTTG
Sbjct: 515 IASEDTTG 522
>XP_006711092
          Length = 1161

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSVEDTTG 8
           ++ EDTTG
Sbjct: 730 IASEDTTG 737
>XP_006711091
          Length = 1161

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSVEDTTG 8
           ++ EDTTG
Sbjct: 730 IASEDTTG 737
>NP_055964
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VSVEDTTGS 9
           +SVED  G+
Sbjct: 689 ISVEDNNGN 697
>NP_001078855
          Length = 179

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SVEDTTGS 9
           S ED TGS
Sbjct: 121 SAEDPTGS 128
>NP_997400
          Length = 1691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  VEDTTG 8
          +EDTTG
Sbjct: 47 LEDTTG 52
>NP_001026
          Length = 4967

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    VSVEDT 6
            VSVEDT
Sbjct: 2111 VSVEDT 2116
>NP_003961
          Length = 1465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   VSVEDTTG 8
           VSV DT G
Sbjct: 982 VSVSDTDG 989
>NP_002827
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VSVEDTT 7
           VSVED T
Sbjct: 367 VSVEDVT 373
>NP_543031
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VSVEDTT 7
           VSVED T
Sbjct: 358 VSVEDVT 364
>NP_543030
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VSVEDTT 7
           VSVED T
Sbjct: 358 VSVEDVT 364
>NP_001034678
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  VEDTTGS 9
          +E+TTGS
Sbjct: 69 LEETTGS 75
>NP_001375
          Length = 489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  VEDTTGS 9
          +E+TTGS
Sbjct: 69 LEETTGS 75
>NP_663780
          Length = 1565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SVEDTTGS 9
            S EDT+G+
Sbjct: 1384 SAEDTSGA 1391
>NP_001257957
          Length = 490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SVEDTTG 8
           SVE TTG
Sbjct: 198 SVEPTTG 204
>NP_777562
          Length = 345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSVEDTTGS 9
           +SVEDT+ S
Sbjct: 312 LSVEDTSHS 320
>NP_056356
          Length = 1093

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   SVEDTTGS 9
           ++EDT+G+
Sbjct: 370 TIEDTSGA 377
>NP_981947
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VEDTTGS 9
           +ED TGS
Sbjct: 145 IEDLTGS 151
>XP_005266741
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   SVEDTTG 8
           +++DTTG
Sbjct: 108 TIDDTTG 114
>XP_005266739
          Length = 801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   SVEDTTG 8
           +++DTTG
Sbjct: 108 TIDDTTG 114
>XP_005272494
          Length = 1670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  VEDTTG 8
          +EDTTG
Sbjct: 47 LEDTTG 52
>XP_005272493
          Length = 1674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  VEDTTG 8
          +EDTTG
Sbjct: 47 LEDTTG 52
>XP_005272492
          Length = 1682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  VEDTTG 8
          +EDTTG
Sbjct: 47 LEDTTG 52
>XP_006716300
          Length = 1445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   VSVEDTTG 8
           VSV DT G
Sbjct: 982 VSVSDTDG 989
>XP_006711873
          Length = 4954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    VSVEDT 6
            VSVEDT
Sbjct: 2110 VSVEDT 2115
>XP_006711872
          Length = 2735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    VSVEDT 6
            VSVEDT
Sbjct: 2121 VSVEDT 2126
>XP_006711871
          Length = 4906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    VSVEDT 6
            VSVEDT
Sbjct: 2121 VSVEDT 2126
>XP_006711870
          Length = 4965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    VSVEDT 6
            VSVEDT
Sbjct: 2121 VSVEDT 2126
>XP_006711869
          Length = 4973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    VSVEDT 6
            VSVEDT
Sbjct: 2121 VSVEDT 2126
>XP_006711868
          Length = 4975

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    VSVEDT 6
            VSVEDT
Sbjct: 2111 VSVEDT 2116
>XP_006711867
          Length = 4977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    VSVEDT 6
            VSVEDT
Sbjct: 2121 VSVEDT 2126
>XP_006711866
          Length = 4984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    VSVEDT 6
            VSVEDT
Sbjct: 2120 VSVEDT 2125
>XP_006711865
          Length = 4985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    VSVEDT 6
            VSVEDT
Sbjct: 2121 VSVEDT 2126
>NP_114097
          Length = 801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   SVEDTTG 8
           +++DTTG
Sbjct: 108 TIDDTTG 114
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.288    0.109    0.262 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 602,744
Number of extensions: 1020
Number of successful extensions: 75
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)

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