Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_003290                                                              18    1135
NP_001272378                                                           17    4312
NP_001272376                                                           17    4312
NP_001272374                                                           17    4312
NP_001272373                                                           17    4312
NP_055842                                                              17    4312
NP_001272377                                                           17    4312
NP_001272379                                                           17    4312
XP_006726664                                                           17    4312
XP_006726663                                                           17    4312
XP_006726662                                                           17    4312
XP_006726661                                                           17    4312
XP_006726660                                                           17    4312
XP_006726659                                                           17    4312
XP_006726658                                                           17    4312
XP_006725292                                                           17    4312
XP_006725291                                                           17    4312
XP_006725290                                                           17    4312
XP_006725289                                                           17    4312
XP_006725288                                                           17    4312
XP_006725287                                                           17    4312
XP_006725286                                                           17    4312
XP_006720929                                                           17    4312
XP_005255233                                                           17    4312
XP_006720928                                                           17    4312
XP_005255231                                                           17    4312
XP_005255230                                                           17    4312
XP_005250166                                                           16    5631
NP_005859                                                              16    5631
NP_057434                                                              16    7355
NP_001185782                                                           16    7355
NP_001185784                                                           16    7355
NP_000761                                                              16    7355
NP_891989                                                              16    7355
NP_001162                                                              16    7355
NP_065972                                                              16    7355
NP_891991                                                              16    7355
NP_001269354                                                           16    7355
NP_006563                                                              16    7355
NP_001230178                                                           16    7355
NP_001230176                                                           16    7355
NP_001034565                                                           16    7355
NP_001165906                                                           16    7355
NP_001070818                                                           16    7355
NP_001230177                                                           16    7355
XP_005255367                                                           16    7355
XP_006725257                                                           16    7355
XP_006725256                                                           16    7355
XP_006720224                                                           16    7355
XP_005267794                                                           16    7355
XP_005267793                                                           16    7355
XP_005267792                                                           16    7355
XP_006720223                                                           16    7355
XP_006717558                                                           16    7355
XP_006717557                                                           16    7355
XP_006717556                                                           16    7355
XP_005252630                                                           16    7355
XP_005252629                                                           16    7355
XP_005252628                                                           16    7355
XP_005252627                                                           16    7355
XP_005252625                                                           16    7355
XP_005252623                                                           16    7355
XP_006717555                                                           16    7355
XP_005252621                                                           16    7355
NP_955523                                                              15    9605
NP_055766                                                              15    9605
NP_955522                                                              15    9605
NP_001626                                                              15    9605
NP_647477                                                              15    9605
XP_006715754                                                           15    9605
XP_006715753                                                           15    9605
XP_006715752                                                           15    9605
>NP_003290
          Length = 803

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   VSQRLTES 8
           VSQRLTES
Sbjct: 636 VSQRLTES 643
>NP_001272378
          Length = 498

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 363 LSQRLQESL 371
>NP_001272376
          Length = 773

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 348 LSQRLQESL 356
>NP_001272374
          Length = 760

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 335 LSQRLQESL 343
>NP_001272373
          Length = 761

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 336 LSQRLQESL 344
>NP_055842
          Length = 788

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 363 LSQRLQESL 371
>NP_001272377
          Length = 697

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 272 LSQRLQESL 280
>NP_001272379
          Length = 429

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 340 LSQRLQESL 348
>XP_006726664
          Length = 516

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 381 LSQRLQESL 389
>XP_006726663
          Length = 761

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 336 LSQRLQESL 344
>XP_006726662
          Length = 773

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 348 LSQRLQESL 356
>XP_006726661
          Length = 779

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 354 LSQRLQESL 362
>XP_006726660
          Length = 788

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 363 LSQRLQESL 371
>XP_006726659
          Length = 797

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 372 LSQRLQESL 380
>XP_006726658
          Length = 806

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 381 LSQRLQESL 389
>XP_006725292
          Length = 516

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 381 LSQRLQESL 389
>XP_006725291
          Length = 761

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 336 LSQRLQESL 344
>XP_006725290
          Length = 773

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 348 LSQRLQESL 356
>XP_006725289
          Length = 779

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 354 LSQRLQESL 362
>XP_006725288
          Length = 788

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 363 LSQRLQESL 371
>XP_006725287
          Length = 797

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 372 LSQRLQESL 380
>XP_006725286
          Length = 806

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 381 LSQRLQESL 389
>XP_006720929
          Length = 516

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 381 LSQRLQESL 389
>XP_005255233
          Length = 773

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 348 LSQRLQESL 356
>XP_006720928
          Length = 779

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 354 LSQRLQESL 362
>XP_005255231
          Length = 797

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 372 LSQRLQESL 380
>XP_005255230
          Length = 806

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQRL ESL
Sbjct: 381 LSQRLQESL 389
>XP_005250166
          Length = 127

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  SQRLTESL 9
          ++RLTESL
Sbjct: 32 NERLTESL 39
>NP_005859
          Length = 118

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  SQRLTESL 9
          ++RLTESL
Sbjct: 32 NERLTESL 39
>NP_057434
          Length = 1377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           ++QRLTE L
Sbjct: 897 LNQRLTEML 905
>NP_001185782
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VSQRLTESL 9
          +SQR+T+ L
Sbjct: 32 ISQRITKGL 40
>NP_001185784
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VSQRLTESL 9
          +SQR+T+ L
Sbjct: 32 ISQRITKGL 40
>NP_000761
          Length = 490

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           +SQR+T+ L
Sbjct: 102 ISQRITKGL 110
>NP_891989
          Length = 2046

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VSQRLTESL 9
            ++QRLTE L
Sbjct: 1610 LNQRLTEML 1618
>NP_001162
          Length = 1503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QRLTESL 9
           QRLTES+
Sbjct: 418 QRLTESV 424
>NP_065972
          Length = 2133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VSQRLTESL 9
            ++QRLTE L
Sbjct: 1610 LNQRLTEML 1618
>NP_891991
          Length = 2090

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VSQRLTESL 9
            ++QRLTE L
Sbjct: 1610 LNQRLTEML 1618
>NP_001269354
          Length = 282

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           ++ RLTESL
Sbjct: 166 LTNRLTESL 174
>NP_006563
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           ++ RLTESL
Sbjct: 261 LTNRLTESL 269
>NP_001230178
          Length = 544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   VSQRLTESL 9
           ++QR+TE+L
Sbjct: 453 LNQRMTENL 461
>NP_001230176
          Length = 491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   VSQRLTESL 9
           ++QR+TE+L
Sbjct: 400 LNQRMTENL 408
>NP_001034565
          Length = 390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   VSQRLTESL 9
           ++QR+TE+L
Sbjct: 299 LNQRMTENL 307
>NP_001165906
          Length = 988

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SQRLTES 8
           +QRLTES
Sbjct: 901 AQRLTES 907
>NP_001070818
          Length = 569

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   VSQRLTESL 9
           ++QR+TE+L
Sbjct: 478 LNQRMTENL 486
>NP_001230177
          Length = 544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   VSQRLTESL 9
           ++QR+TE+L
Sbjct: 453 LNQRMTENL 461
>XP_005255367
          Length = 972

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QRLTESL 9
           QRLTES+
Sbjct: 519 QRLTESV 525
>XP_006725257
          Length = 972

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QRLTESL 9
           QRLTES+
Sbjct: 519 QRLTESV 525
>XP_006725256
          Length = 979

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QRLTESL 9
           QRLTES+
Sbjct: 519 QRLTESV 525
>XP_006720224
          Length = 1276

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           ++QRLTE L
Sbjct: 897 LNQRLTEML 905
>XP_005267794
          Length = 1379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           ++QRLTE L
Sbjct: 897 LNQRLTEML 905
>XP_005267793
          Length = 1390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           ++QRLTE L
Sbjct: 867 LNQRLTEML 875
>XP_005267792
          Length = 1420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSQRLTESL 9
           ++QRLTE L
Sbjct: 897 LNQRLTEML 905
>XP_006720223
          Length = 1989

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VSQRLTESL 9
            ++QRLTE L
Sbjct: 1610 LNQRLTEML 1618
>XP_006717558
          Length = 1908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSQRLTES 8
           ++QR+TES
Sbjct: 864 INQRVTES 871
>XP_006717557
          Length = 1940

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSQRLTES 8
           ++QR+TES
Sbjct: 896 INQRVTES 903
>XP_006717556
          Length = 2024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSQRLTES 8
           ++QR+TES
Sbjct: 980 INQRVTES 987
>XP_005252630
          Length = 2256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VSQRLTES 8
            ++QR+TES
Sbjct: 1212 INQRVTES 1219
>XP_005252629
          Length = 2256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VSQRLTES 8
            ++QR+TES
Sbjct: 1212 INQRVTES 1219
>XP_005252628
          Length = 2256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VSQRLTES 8
            ++QR+TES
Sbjct: 1212 INQRVTES 1219
>XP_005252627
          Length = 2256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VSQRLTES 8
            ++QR+TES
Sbjct: 1212 INQRVTES 1219
>XP_005252625
          Length = 2277

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VSQRLTES 8
            ++QR+TES
Sbjct: 1233 INQRVTES 1240
>XP_005252623
          Length = 2302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VSQRLTES 8
            ++QR+TES
Sbjct: 1258 INQRVTES 1265
>XP_006717555
          Length = 2328

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VSQRLTES 8
            ++QR+TES
Sbjct: 1284 INQRVTES 1291
>XP_005252621
          Length = 2334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VSQRLTES 8
            ++QR+TES
Sbjct: 1290 INQRVTES 1297
>NP_955523
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   QRLTES 8
           QRLTES
Sbjct: 234 QRLTES 239
>NP_055766
          Length = 407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   QRLTES 8
           QRLTES
Sbjct: 234 QRLTES 239
>NP_955522
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   QRLTES 8
           QRLTES
Sbjct: 234 QRLTES 239
>NP_001626
          Length = 695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SQRLTESL 9
          S +LTESL
Sbjct: 74 SMKLTESL 81
>NP_647477
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SQRLTESL 9
          S +LTESL
Sbjct: 74 SMKLTESL 81
>XP_006715754
          Length = 392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SQRLTESL 9
          S +LTESL
Sbjct: 74 SMKLTESL 81
>XP_006715753
          Length = 819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SQRLTESL 9
          S +LTESL
Sbjct: 74 SMKLTESL 81
>XP_006715752
          Length = 1225

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SQRLTESL 9
          S +LTESL
Sbjct: 74 SMKLTESL 81
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.306    0.117    0.259 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 350,823
Number of extensions: 590
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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