Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_009057                                                              16    7355
NP_056099                                                              16    7355
NP_001264044                                                           16    7355
NP_075463                                                              16    7355
XP_006719812                                                           16    7355
XP_006710565                                                           16    7355
XP_006710564                                                           16    7355
XP_005270743                                                           16    7355
>NP_009057
          Length = 806

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VSQLLTII 8
           VSQLLT++
Sbjct: 325 VSQLLTLM 332
>NP_056099
          Length = 3375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   VSQLLTIIT 9
           ++QLL+I+T
Sbjct: 815 IAQLLSILT 823
>NP_001264044
          Length = 4516

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VSQLLTIIT 9
            +SQL T+IT
Sbjct: 1777 ISQLNTLIT 1785
>NP_075463
          Length = 3013

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SQLLTIIT 9
           S+L+TIIT
Sbjct: 428 SRLITIIT 435
>XP_006719812
          Length = 3019

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SQLLTIIT 9
           S+L+TIIT
Sbjct: 425 SRLITIIT 432
>XP_006710565
          Length = 3140

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   VSQLLTIIT 9
           ++QLL+I+T
Sbjct: 523 IAQLLSILT 531
>XP_006710564
          Length = 3432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   VSQLLTIIT 9
           ++QLL+I+T
Sbjct: 815 IAQLLSILT 823
>XP_005270743
          Length = 3453

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   VSQLLTIIT 9
           ++QLL+I+T
Sbjct: 836 IAQLLSILT 844
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.138    0.316 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 311,923
Number of extensions: 323
Number of successful extensions: 8
Number of sequences better than 10000.0: 8
Number of HSP's gapped: 8
Number of HSP's successfully gapped: 8
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package