Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001257436                                                           20     299
NP_001257437                                                           20     299
NP_006281                                                              20     299
XP_006715618                                                           20     299
XP_005267176                                                           20     299
NP_542411                                                              17    3301
XP_006725001                                                           17    3301
NP_057452                                                              17    4312
NP_057417                                                              17    4312
NP_443082                                                              17    4312
XP_005255284                                                           17    4312
XP_005255283                                                           17    4312
XP_006720936                                                           17    4312
XP_006720935                                                           17    4312
XP_005255282                                                           17    4312
NP_065880                                                              16    5631
NP_001129392                                                           16    5631
NP_001193486                                                           16    5631
XP_005251580                                                           16    5631
NP_115970                                                              16    7355
NP_000616                                                              16    7355
NP_001269356                                                           16    7355
NP_001269355                                                           16    7355
NP_002640                                                              16    7355
NP_569056                                                              16    7355
NP_001193809                                                           16    7355
NP_001093633                                                           16    7355
NP_001027449                                                           16    7355
NP_077278                                                              16    7355
NP_055061                                                              16    7355
NP_001138722                                                           16    7355
NP_001092049                                                           16    7355
XP_006726574                                                           16    7355
XP_006724446                                                           16    7355
XP_005254186                                                           16    7355
XP_005250500                                                           16    7355
XP_006715862                                                           16    7355
XP_005249952                                                           16    7355
XP_005249951                                                           16    7355
NP_003686                                                              16    7355
NP_006456                                                              16    7355
NP_001186692                                                           15    9605
NP_001273897                                                           15    9605
NP_005345                                                              15    9605
NP_055990                                                              15    9605
NP_002837                                                              15    9605
NP_001186693                                                           15    9605
NP_054865                                                              15    9605
NP_115852                                                              15    9605
NP_115853                                                              15    9605
NP_065823                                                              15    9605
NP_057279                                                              15    9605
NP_001271188                                                           15    9605
XP_005250619                                                           15    9605
XP_006714541                                                           15    9605
XP_005248375                                                           15    9605
XP_005265050                                                           15    9605
XP_005265049                                                           15    9605
XP_006713135                                                           15    9605
NP_060504                                                              15    9605
>NP_001257436
          Length = 790

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VSPTSSRFQ 9
           VSPT+SRFQ
Sbjct: 644 VSPTASRFQ 652
>NP_001257437
          Length = 790

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VSPTSSRFQ 9
           VSPT+SRFQ
Sbjct: 644 VSPTASRFQ 652
>NP_006281
          Length = 790

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VSPTSSRFQ 9
           VSPT+SRFQ
Sbjct: 644 VSPTASRFQ 652
>XP_006715618
          Length = 577

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VSPTSSRFQ 9
           VSPT+SRFQ
Sbjct: 431 VSPTASRFQ 439
>XP_005267176
          Length = 790

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VSPTSSRFQ 9
           VSPT+SRFQ
Sbjct: 644 VSPTASRFQ 652
>NP_542411
          Length = 1736

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VSPTSSRFQ 9
           V PT+ RFQ
Sbjct: 320 VPPTADRFQ 328
>XP_006725001
          Length = 387

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SPTSSRFQ 9
          SPT+ RFQ
Sbjct: 66 SPTTPRFQ 73
>NP_057452
          Length = 558

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VSPTSSRF 8
          V PTS+RF
Sbjct: 41 VHPTSTRF 48
>NP_057417
          Length = 2752

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VSPTSSRFQ 9
            +SP  SRFQ
Sbjct: 1131 MSPEQSRFQ 1139
>NP_443082
          Length = 222

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VSPTSSRFQ 9
           V P S+RFQ
Sbjct: 168 VDPRSARFQ 176
>XP_005255284
          Length = 2581

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VSPTSSRFQ 9
            +SP  SRFQ
Sbjct: 1131 MSPEQSRFQ 1139
>XP_005255283
          Length = 2751

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VSPTSSRFQ 9
            +SP  SRFQ
Sbjct: 1131 MSPEQSRFQ 1139
>XP_006720936
          Length = 2751

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VSPTSSRFQ 9
            +SP  SRFQ
Sbjct: 1130 MSPEQSRFQ 1138
>XP_006720935
          Length = 2752

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VSPTSSRFQ 9
            +SP  SRFQ
Sbjct: 1131 MSPEQSRFQ 1139
>XP_005255282
          Length = 2752

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VSPTSSRFQ 9
            +SP  SRFQ
Sbjct: 1131 MSPEQSRFQ 1139
>NP_065880
          Length = 1423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSPTSSRF 8
           ++P SSRF
Sbjct: 230 ITPVSSRF 237
>NP_001129392
          Length = 1165

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSPTSSRF 8
           ++P SSRF
Sbjct: 230 ITPVSSRF 237
>NP_001193486
          Length = 1386

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSPTSSRF 8
           ++P SSRF
Sbjct: 230 ITPVSSRF 237
>XP_005251580
          Length = 1422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSPTSSRF 8
           ++P SSRF
Sbjct: 229 ITPVSSRF 236
>NP_115970
          Length = 521

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VSPTSSR 7
           ++PTSSR
Sbjct: 305 ITPTSSR 311
>NP_000616
          Length = 1153

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SPTSSR 7
           SPTSSR
Sbjct: 745 SPTSSR 750
>NP_001269356
          Length = 1102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SPTSSRFQ 9
           SPT  +FQ
Sbjct: 915 SPTEEKFQ 922
>NP_001269355
          Length = 1102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SPTSSRFQ 9
           SPT  +FQ
Sbjct: 915 SPTEEKFQ 922
>NP_002640
          Length = 1102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SPTSSRFQ 9
           SPT  +FQ
Sbjct: 915 SPTEEKFQ 922
>NP_569056
          Length = 912

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SPTSSR 7
           SPTSSR
Sbjct: 202 SPTSSR 207
>NP_001193809
          Length = 706

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SPTSSR 7
           SPTSSR
Sbjct: 202 SPTSSR 207
>NP_001093633
          Length = 821

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SPTSSR 7
           SPTSSR
Sbjct: 111 SPTSSR 116
>NP_001027449
          Length = 130

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  SPTSSRF 8
          +PTS+RF
Sbjct: 53 APTSTRF 59
>NP_077278
          Length = 520

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  SPTSSRF 8
          +PTS+RF
Sbjct: 53 APTSTRF 59
>NP_055061
          Length = 3014

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    SPTSSR 7
            SPTSSR
Sbjct: 2960 SPTSSR 2965
>NP_001138722
          Length = 484

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SPTSSRF 8
           SPTSS F
Sbjct: 95  SPTSSAF 101
>NP_001092049
          Length = 904

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SPTSSR 7
           SPTSSR
Sbjct: 193 SPTSSR 198
>XP_006726574
          Length = 446

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SPTSSR 7
           SPTSSR
Sbjct: 397 SPTSSR 402
>XP_006724446
          Length = 3019

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    SPTSSR 7
            SPTSSR
Sbjct: 2960 SPTSSR 2965
>XP_005254186
          Length = 561

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SPTSSR 7
           SPTSSR
Sbjct: 543 SPTSSR 548
>XP_005250500
          Length = 1102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SPTSSRFQ 9
           SPT  +FQ
Sbjct: 915 SPTEEKFQ 922
>XP_006715862
          Length = 346

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VSPTSSR 7
           ++PTSSR
Sbjct: 130 ITPTSSR 136
>XP_005249952
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VSPTSSR 7
           ++PTSSR
Sbjct: 305 ITPTSSR 311
>XP_005249951
          Length = 419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VSPTSSR 7
           ++PTSSR
Sbjct: 305 ITPTSSR 311
>NP_003686
          Length = 128

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  VSPTSSRF 8
          V P SSRF
Sbjct: 37 VCPASSRF 44
>NP_006456
          Length = 560

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SPTSSR 7
           SPTSSR
Sbjct: 542 SPTSSR 547
>NP_001186692
          Length = 950

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SPTSSRFQ 9
           SPTSS  Q
Sbjct: 415 SPTSSEVQ 422
>NP_001273897
          Length = 304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  SPTSSRF 8
          +PTSS+F
Sbjct: 74 TPTSSQF 80
>NP_005345
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SPTSSRF 8
           +PTSS+F
Sbjct: 117 TPTSSQF 123
>NP_055990
          Length = 2754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VSPTSSRFQ 9
            V PT S+F+
Sbjct: 1718 VQPTMSQFE 1726
>NP_002837
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SPTSSRFQ 9
           SPTSS  Q
Sbjct: 415 SPTSSEVQ 422
>NP_001186693
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SPTSSRFQ 9
           SPTSS  Q
Sbjct: 325 SPTSSEVQ 332
>NP_054865
          Length = 243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  PTSSRFQ 9
          P SSR+Q
Sbjct: 90 PASSRYQ 96
>NP_115852
          Length = 243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  PTSSRFQ 9
          P SSR+Q
Sbjct: 90 PASSRYQ 96
>NP_115853
          Length = 243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  PTSSRFQ 9
          P SSR+Q
Sbjct: 90 PASSRYQ 96
>NP_065823
          Length = 695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VSPTSS 6
           VSPTSS
Sbjct: 375 VSPTSS 380
>NP_057279
          Length = 1780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   PTSSRFQ 9
           P SS+FQ
Sbjct: 289 PVSSKFQ 295
>NP_001271188
          Length = 1820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   PTSSRFQ 9
           P SS+FQ
Sbjct: 289 PVSSKFQ 295
>XP_005250619
          Length = 243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  PTSSRFQ 9
          P SSR+Q
Sbjct: 90 PASSRYQ 96
>XP_006714541
          Length = 387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  VSPTSSR 7
          + PTSSR
Sbjct: 80 IEPTSSR 86
>XP_005248375
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  VSPTSSR 7
          + PTSSR
Sbjct: 79 IEPTSSR 85
>XP_005265050
          Length = 1578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VSPTSSRFQ 9
           V PT S+F+
Sbjct: 542 VQPTMSQFE 550
>XP_005265049
          Length = 2720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VSPTSSRFQ 9
            V PT S+F+
Sbjct: 1684 VQPTMSQFE 1692
>XP_006713135
          Length = 2727

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VSPTSSRFQ 9
            V PT S+F+
Sbjct: 1691 VQPTMSQFE 1699
>NP_060504
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  VSPTSSR 7
          + PTSSR
Sbjct: 80 IEPTSSR 86
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.115    0.305 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 737,895
Number of extensions: 1121
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package