Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001006608                                                           18    1935
NP_955372                                                              18    1935
NP_055649                                                              18    1935
XP_005275724                                                           18    1935
XP_005275722                                                           18    1935
XP_005275721                                                           18    1935
XP_006725345                                                           18    1935
XP_006725344                                                           18    1935
XP_005275719                                                           18    1935
XP_006725343                                                           18    1935
XP_006725342                                                           18    1935
XP_005275717                                                           18    1935
XP_005275716                                                           18    1935
XP_005257941                                                           18    1935
XP_005257940                                                           18    1935
XP_006722274                                                           18    1935
XP_006722273                                                           18    1935
XP_005257939                                                           18    1935
XP_006722272                                                           18    1935
XP_005257937                                                           18    1935
XP_005257936                                                           18    1935
XP_005257935                                                           18    1935
XP_006722271                                                           18    1935
NP_004110                                                              17    2528
XP_006711469                                                           17    3301
XP_005245352                                                           17    3301
NP_542437                                                              16    7355
NP_061197                                                              16    7355
NP_542435                                                              16    7355
NP_542436                                                              16    7355
NP_003740                                                              16    7355
NP_001276953                                                           16    7355
NP_714912                                                              16    7355
NP_001276952                                                           16    7355
NP_005526                                                              16    7355
XP_006722804                                                           16    7355
NP_078966                                                              15    9605
NP_004127                                                              15    9605
NP_001186028                                                           15    9605
NP_001186026                                                           15    9605
NP_001186027                                                           15    9605
NP_001186025                                                           15    9605
NP_001273720                                                           15    9605
NP_006107                                                              15    9605
NP_001483                                                              15    9605
NP_060501                                                              15    9605
NP_003924                                                              15    9605
NP_056453                                                              15    9605
NP_079363                                                              15    9605
NP_003176                                                              15    9605
NP_955400                                                              15    9605
NP_001273393                                                           15    9605
XP_005259010                                                           15    9605
XP_006714093                                                           15    9605
XP_005248183                                                           15    9605
XP_005264894                                                           15    9605
NP_065172                                                              15    9605
>NP_001006608
          Length = 1700

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>NP_955372
          Length = 1634

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>NP_055649
          Length = 1700

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>XP_005275724
          Length = 894

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>XP_005275722
          Length = 969

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>XP_005275721
          Length = 1018

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>XP_006725345
          Length = 1600

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>XP_006725344
          Length = 1606

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 508 VSPSVTVQL 516
>XP_005275719
          Length = 1625

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>XP_006725343
          Length = 1635

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>XP_006725342
          Length = 1651

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>XP_005275717
          Length = 1665

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>XP_005275716
          Length = 1676

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>XP_005257941
          Length = 969

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>XP_005257940
          Length = 1018

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>XP_006722274
          Length = 1576

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>XP_006722273
          Length = 1600

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>XP_005257939
          Length = 1606

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 508 VSPSVTVQL 516
>XP_006722272
          Length = 1635

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>XP_005257937
          Length = 1651

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>XP_005257936
          Length = 1665

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>XP_005257935
          Length = 1676

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>XP_006722271
          Length = 1700

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VSPSITLQV 9
           VSPS+T+Q+
Sbjct: 602 VSPSVTVQL 610
>NP_004110
          Length = 993

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VSPSITLQV 9
          VS SITLQV
Sbjct: 85 VSASITLQV 93
>XP_006711469
          Length = 357

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  VSPSITLQV 9
          +SPS+TL+V
Sbjct: 14 LSPSLTLKV 22
>XP_005245352
          Length = 357

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  VSPSITLQV 9
          +SPS+TL+V
Sbjct: 14 LSPSLTLKV 22
>NP_542437
          Length = 839

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VSPSITLQ 8
          VSP IT+Q
Sbjct: 78 VSPVITIQ 85
>NP_061197
          Length = 839

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VSPSITLQ 8
          VSP IT+Q
Sbjct: 78 VSPVITIQ 85
>NP_542435
          Length = 839

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VSPSITLQ 8
          VSP IT+Q
Sbjct: 78 VSPVITIQ 85
>NP_542436
          Length = 839

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VSPSITLQ 8
          VSP IT+Q
Sbjct: 78 VSPVITIQ 85
>NP_003740
          Length = 1338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PSITLQV 9
           PS+TLQ+
Sbjct: 236 PSVTLQL 242
>NP_001276953
          Length = 702

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SPSITLQV 9
           SP +TLQ+
Sbjct: 166 SPEVTLQL 173
>NP_714912
          Length = 381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SPSITLQV 9
           SP +TLQ+
Sbjct: 126 SPEVTLQL 133
>NP_001276952
          Length = 660

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SPSITLQV 9
           SP +TLQ+
Sbjct: 126 SPEVTLQL 133
>NP_005526
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SPSITLQV 9
           SP +TLQ+
Sbjct: 126 SPEVTLQL 133
>XP_006722804
          Length = 674

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SPSITLQV 9
           SP +TLQ+
Sbjct: 126 SPEVTLQL 133
>NP_078966
          Length = 14507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    SPSITL 7
            SPSITL
Sbjct: 2308 SPSITL 2313
>NP_004127
          Length = 963

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VSPSITLQV 9
           +SP ITL +
Sbjct: 918 LSPGITLNI 926
>NP_001186028
          Length = 1124

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSPSITLQV 9
           +SP +TL+V
Sbjct: 587 LSPKMTLEV 595
>NP_001186026
          Length = 1152

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSPSITLQV 9
           +SP +TL+V
Sbjct: 615 LSPKMTLEV 623
>NP_001186027
          Length = 1129

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSPSITLQV 9
           +SP +TL+V
Sbjct: 592 LSPKMTLEV 600
>NP_001186025
          Length = 1116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSPSITLQV 9
           +SP +TL+V
Sbjct: 579 LSPKMTLEV 587
>NP_001273720
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSPSITLQV 9
           ++P+ITL V
Sbjct: 500 IAPAITLTV 508
>NP_006107
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SPSITLQ 8
           SP++TLQ
Sbjct: 438 SPTLTLQ 444
>NP_001483
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  SPSITLQ 8
          SP +TLQ
Sbjct: 82 SPGVTLQ 88
>NP_060501
          Length = 1151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SPSITLQ 8
            +PS+TLQ
Sbjct: 1001 TPSLTLQ 1007
>NP_003924
          Length = 1187

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSPSITLQV 9
           +SP +TL+V
Sbjct: 650 LSPKMTLEV 658
>NP_056453
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SPSITLQV 9
           SP ITL++
Sbjct: 449 SPDITLKI 456
>NP_079363
          Length = 699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSPSITLQV 9
           ++P+ITL V
Sbjct: 527 IAPAITLTV 535
>NP_003176
          Length = 1085

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   VSPSITLQ 8
           V PS TLQ
Sbjct: 534 VQPSATLQ 541
>NP_955400
          Length = 789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SPSITLQV 9
           SP ITL++
Sbjct: 441 SPDITLKI 448
>NP_001273393
          Length = 1169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSPSITLQV 9
           +SP +TL+V
Sbjct: 632 LSPKMTLEV 640
>XP_005259010
          Length = 1261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VSPSITLQV 9
            +SPS+TL +
Sbjct: 1083 LSPSLTLSL 1091
>XP_006714093
          Length = 511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSPSITLQV 9
           ++P+ITL V
Sbjct: 339 IAPAITLTV 347
>XP_005248183
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSPSITLQV 9
           ++P+ITL V
Sbjct: 441 IAPAITLTV 449
>XP_005264894
          Length = 1070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SPSITLQ 8
           +PS+TLQ
Sbjct: 920 TPSLTLQ 926
>NP_065172
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VSPSITLQV 9
           + PS++LQ+
Sbjct: 287 IYPSVSLQI 295
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.125    0.310 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 785,884
Number of extensions: 1170
Number of successful extensions: 57
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package