Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           19     665
NP_001185763                                                           19     665
NP_055459                                                              19     665
XP_006726410                                                           19     665
XP_006711719                                                           19     665
XP_006711718                                                           19     665
XP_006711717                                                           19     665
XP_006711716                                                           19     665
XP_006711715                                                           19     665
XP_006711714                                                           19     665
XP_006711713                                                           19     665
XP_006711712                                                           19     665
XP_006711711                                                           19     665
XP_006711710                                                           19     665
XP_006711709                                                           19     665
XP_005277503                                                           19     665
XP_005273038                                                           19     665
XP_006711708                                                           19     665
XP_005277500                                                           19     665
XP_006711707                                                           19     665
XP_005277499                                                           19     665
XP_006711706                                                           19     665
XP_006711705                                                           19     665
XP_006711164                                                           19     665
XP_005276153                                                           19     665
XP_003846805                                                           19     665
NP_000833                                                              17    3301
NP_001137303                                                           17    3301
NP_060158                                                              17    3301
XP_006718893                                                           17    3301
XP_006718892                                                           17    3301
XP_006718891                                                           17    3301
XP_005252120                                                           17    3301
XP_006717212                                                           17    3301
NP_001264994                                                           17    4312
NP_001264995                                                           17    4312
NP_001264996                                                           17    4312
NP_001264993                                                           17    4312
NP_063941                                                              17    4312
XP_006715531                                                           17    4312
XP_006715530                                                           17    4312
NP_997716                                                              16    5631
NP_001124319                                                           16    5631
NP_004199                                                              16    5631
NP_665812                                                              16    5631
NP_665811                                                              16    5631
NP_001165694                                                           16    7355
NP_443731                                                              16    7355
NP_001034842                                                           16    7355
XP_006712080                                                           16    7355
XP_006712079                                                           16    7355
NP_006199                                                              15    9605
NP_001012267                                                           15    9605
NP_001273898                                                           15    9605
NP_001269122                                                           15    9605
NP_001269121                                                           15    9605
NP_057218                                                              15    9605
NP_919412                                                              15    9605
NP_001273900                                                           15    9605
NP_002928                                                              15    9605
XP_006716561                                                           15    9605
XP_005250812                                                           15    9605
XP_005272028                                                           15    9605
XP_005272027                                                           15    9605
XP_005272026                                                           15    9605
XP_005272025                                                           15    9605
XP_005272024                                                           15    9605
NP_001017372                                                           15    9605
NP_054750                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2099 VSLVRSACS 2107
>NP_001185763
          Length = 2362

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2205 VSLVRSACS 2213
>NP_055459
          Length = 2346

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2205 VSLVRSACS 2213
>XP_006726410
          Length = 2087

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 1946 VSLVRSACS 1954
>XP_006711719
          Length = 2302

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2161 VSLVRSACS 2169
>XP_006711718
          Length = 1436

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 1212 VSLVRSACS 1220
>XP_006711717
          Length = 2385

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2161 VSLVRSACS 2169
>XP_006711716
          Length = 2411

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2270 VSLVRSACS 2278
>XP_006711715
          Length = 2428

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2204 VSLVRSACS 2212
>XP_006711714
          Length = 2429

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2205 VSLVRSACS 2213
>XP_006711713
          Length = 2432

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2208 VSLVRSACS 2216
>XP_006711712
          Length = 2473

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2249 VSLVRSACS 2257
>XP_006711711
          Length = 2482

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2258 VSLVRSACS 2266
>XP_006711710
          Length = 2494

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2270 VSLVRSACS 2278
>XP_006711709
          Length = 2495

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2271 VSLVRSACS 2279
>XP_005277503
          Length = 2498

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2368 VSLVRSACS 2376
>XP_005273038
          Length = 2509

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2368 VSLVRSACS 2376
>XP_006711708
          Length = 2512

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2288 VSLVRSACS 2296
>XP_005277500
          Length = 2525

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2368 VSLVRSACS 2376
>XP_006711707
          Length = 2553

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2329 VSLVRSACS 2337
>XP_005277499
          Length = 2561

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2368 VSLVRSACS 2376
>XP_006711706
          Length = 2591

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2367 VSLVRSACS 2375
>XP_006711705
          Length = 2592

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 2368 VSLVRSACS 2376
>XP_006711164
          Length = 2087

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLVRSVCS 9
            VSLVRS CS
Sbjct: 1946 VSLVRSACS 1954
>XP_005276153
          Length = 267

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VSLVRSVCS 9
           VSLVRS CS
Sbjct: 162 VSLVRSACS 170
>XP_003846805
          Length = 306

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VSLVRSVCS 9
           VSLVRS CS
Sbjct: 201 VSLVRSACS 209
>NP_000833
          Length = 1180

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SLVRSVCS 9
           +++RSVCS
Sbjct: 505 NIIRSVCS 512
>NP_001137303
          Length = 1212

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SLVRSVCS 9
           +++RSVCS
Sbjct: 505 NIIRSVCS 512
>NP_060158
          Length = 402

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VSLVRSVC 8
           +SLVRS+C
Sbjct: 114 LSLVRSLC 121
>XP_006718893
          Length = 1180

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SLVRSVCS 9
           +++RSVCS
Sbjct: 505 NIIRSVCS 512
>XP_006718892
          Length = 1212

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SLVRSVCS 9
           +++RSVCS
Sbjct: 505 NIIRSVCS 512
>XP_006718891
          Length = 1212

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SLVRSVCS 9
           +++RSVCS
Sbjct: 505 NIIRSVCS 512
>XP_005252120
          Length = 193

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VSLVRSVC 8
           +SLVRS+C
Sbjct: 114 LSLVRSLC 121
>XP_006717212
          Length = 401

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VSLVRSVC 8
           +SLVRS+C
Sbjct: 114 LSLVRSLC 121
>NP_001264994
          Length = 906

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LVRSVCS 9
           +VRSVCS
Sbjct: 519 VVRSVCS 525
>NP_001264995
          Length = 906

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LVRSVCS 9
           +VRSVCS
Sbjct: 519 VVRSVCS 525
>NP_001264996
          Length = 908

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LVRSVCS 9
           +VRSVCS
Sbjct: 519 VVRSVCS 525
>NP_001264993
          Length = 1194

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LVRSVCS 9
           +VRSVCS
Sbjct: 519 VVRSVCS 525
>NP_063941
          Length = 323

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSLVRSVCS 9
           +SLV S+C+
Sbjct: 126 ISLVASICN 134
>XP_006715531
          Length = 1029

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LVRSVCS 9
           +VRSVCS
Sbjct: 519 VVRSVCS 525
>XP_006715530
          Length = 906

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LVRSVCS 9
           +VRSVCS
Sbjct: 519 VVRSVCS 525
>NP_997716
          Length = 227

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SLVRSVCS 9
          SLV+S CS
Sbjct: 26 SLVQSACS 33
>NP_001124319
          Length = 324

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VSLVRSVC 8
          V LVR+VC
Sbjct: 17 VPLVRTVC 24
>NP_004199
          Length = 613

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VSLVRSVC 8
          V LVR+VC
Sbjct: 17 VPLVRTVC 24
>NP_665812
          Length = 326

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VSLVRSVC 8
          V LVR+VC
Sbjct: 17 VPLVRTVC 24
>NP_665811
          Length = 609

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VSLVRSVC 8
          V LVR+VC
Sbjct: 17 VPLVRTVC 24
>NP_001165694
          Length = 268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   SLVRSVC 8
           SLVR +C
Sbjct: 173 SLVRKIC 179
>NP_443731
          Length = 237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   SLVRSVC 8
           SLVR +C
Sbjct: 142 SLVRKIC 148
>NP_001034842
          Length = 1958

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    VSLVRSVC 8
            V  VRSVC
Sbjct: 1646 VECVRSVC 1653
>XP_006712080
          Length = 924

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   VSLVRSVC 8
           V  VRSVC
Sbjct: 612 VECVRSVC 619
>XP_006712079
          Length = 1683

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    VSLVRSVC 8
            V  VRSVC
Sbjct: 1371 VECVRSVC 1378
>NP_006199
          Length = 925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VSLVRSVC 8
          +SLV SVC
Sbjct: 78 LSLVLSVC 85
>NP_001012267
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   SLVRSVCS 9
           SL++S+C+
Sbjct: 277 SLIKSLCA 284
>NP_001273898
          Length = 176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   SLVRSVCS 9
           SL++S+C+
Sbjct: 165 SLIKSLCA 172
>NP_001269122
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4  VRSVCS 9
          +RS+CS
Sbjct: 81 IRSICS 86
>NP_001269121
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4  VRSVCS 9
          +RS+CS
Sbjct: 81 IRSICS 86
>NP_057218
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLVRSVCS 9
           SL+RSV S
Sbjct: 202 SLIRSVAS 209
>NP_919412
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4  VRSVCS 9
          +RS+CS
Sbjct: 81 IRSICS 86
>NP_001273900
          Length = 115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   SLVRSVCS 9
           SL++S+C+
Sbjct: 104 SLIKSLCA 111
>NP_002928
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4  VRSVCS 9
          +RS+CS
Sbjct: 81 IRSICS 86
>XP_006716561
          Length = 304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLVRSVCS 9
           SL+RSV S
Sbjct: 202 SLIRSVAS 209
>XP_005250812
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLVRSVCS 9
           SL+RSV S
Sbjct: 202 SLIRSVAS 209
>XP_005272028
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSLVRSVC 8
           VSL++S C
Sbjct: 212 VSLLKSTC 219
>XP_005272027
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSLVRSVC 8
           VSL++S C
Sbjct: 212 VSLLKSTC 219
>XP_005272026
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSLVRSVC 8
           VSL++S C
Sbjct: 212 VSLLKSTC 219
>XP_005272025
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSLVRSVC 8
           VSL++S C
Sbjct: 212 VSLLKSTC 219
>XP_005272024
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSLVRSVC 8
           VSL++S C
Sbjct: 212 VSLLKSTC 219
>NP_001017372
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSLVRSVC 8
           VSL++S C
Sbjct: 212 VSLLKSTC 219
>NP_054750
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSLVRSVC 8
           VSL++S C
Sbjct: 212 VSLLKSTC 219
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.127    0.351 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 465,627
Number of extensions: 567
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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