Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000262                                                              16    7355
XP_006722542                                                           16    7355
XP_005258336                                                           16    7355
XP_005258335                                                           16    7355
XP_005258334                                                           16    7355
NP_076406                                                              16    7355
NP_002967                                                              15    9605
XP_006712745                                                           15    9605
XP_006712744                                                           15    9605
XP_006712743                                                           15    9605
>NP_000262
          Length = 1278

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VSLVNIIL 8
            VSLVN+++
Sbjct: 1152 VSLVNLVM 1159
>XP_006722542
          Length = 1273

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VSLVNIIL 8
            VSLVN+++
Sbjct: 1169 VSLVNLVM 1176
>XP_005258336
          Length = 1286

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VSLVNIIL 8
            VSLVN+++
Sbjct: 1152 VSLVNLVM 1159
>XP_005258335
          Length = 1295

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VSLVNIIL 8
            VSLVN+++
Sbjct: 1169 VSLVNLVM 1176
>XP_005258334
          Length = 1303

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VSLVNIIL 8
            VSLVN+++
Sbjct: 1169 VSLVNLVM 1176
>NP_076406
          Length = 312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  VSLVNIILL 9
          +SL++IIL+
Sbjct: 41 ISLIDIILI 49
>NP_002967
          Length = 1682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    SLVNIILL 9
            +L+NIILL
Sbjct: 1379 ALLNIILL 1386
>XP_006712745
          Length = 1682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    SLVNIILL 9
            +L+NIILL
Sbjct: 1379 ALLNIILL 1386
>XP_006712744
          Length = 1682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    SLVNIILL 9
            +L+NIILL
Sbjct: 1379 ALLNIILL 1386
>XP_006712743
          Length = 1682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    SLVNIILL 9
            +L+NIILL
Sbjct: 1379 ALLNIILL 1386
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.339    0.159    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 313,423
Number of extensions: 510
Number of successful extensions: 10
Number of sequences better than 10000.0: 10
Number of HSP's gapped: 10
Number of HSP's successfully gapped: 10
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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