Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001275701                                                           19     869
NP_004561                                                              19     869
XP_005253450                                                           19     869
XP_006719151                                                           19     869
NP_597703                                                              16    7355
NP_001263272                                                           16    7355
NP_001138811                                                           16    7355
NP_002383                                                              16    7355
NP_001137472                                                           16    7355
NP_001177739                                                           16    7355
NP_001071153                                                           16    7355
NP_001138809                                                           16    7355
XP_005276439                                                           16    7355
XP_005276438                                                           16    7355
XP_006719463                                                           16    7355
XP_006719462                                                           16    7355
XP_005268929                                                           16    7355
XP_006717918                                                           16    7355
XP_006717917                                                           16    7355
XP_006717916                                                           16    7355
XP_005269893                                                           16    7355
XP_005271857                                                           16    7355
XP_006717684                                                           16    7355
XP_006717682                                                           16    7355
XP_005271854                                                           16    7355
XP_006710000                                                           16    7355
NP_001071133                                                           16    7355
>NP_001275701
          Length = 1486

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VSLSFDQIV 9
          VSL FDQIV
Sbjct: 36 VSLGFDQIV 44
>NP_004561
          Length = 1445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VSLSFDQIV 9
          VSL FDQIV
Sbjct: 36 VSLGFDQIV 44
>XP_005253450
          Length = 1486

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VSLSFDQIV 9
          VSL FDQIV
Sbjct: 36 VSLGFDQIV 44
>XP_006719151
          Length = 1486

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VSLSFDQIV 9
          VSL FDQIV
Sbjct: 36 VSLGFDQIV 44
>NP_597703
          Length = 663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  VSLSFDQ 7
          VSL FDQ
Sbjct: 13 VSLEFDQ 19
>NP_001263272
          Length = 686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  VSLSFDQ 7
          VSL FDQ
Sbjct: 13 VSLEFDQ 19
>NP_001138811
          Length = 442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VSLSFDQ 7
           +SLSFD+
Sbjct: 140 ISLSFDE 146
>NP_002383
          Length = 497

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VSLSFDQ 7
           +SLSFD+
Sbjct: 195 ISLSFDE 201
>NP_001137472
          Length = 686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  VSLSFDQ 7
          VSL FDQ
Sbjct: 13 VSLEFDQ 19
>NP_001177739
          Length = 658

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  VSLSFDQ 7
          VSL FDQ
Sbjct: 13 VSLEFDQ 19
>NP_001071153
          Length = 663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  VSLSFDQ 7
          VSL FDQ
Sbjct: 13 VSLEFDQ 19
>NP_001138809
          Length = 444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VSLSFDQ 7
           +SLSFD+
Sbjct: 189 ISLSFDE 195
>XP_005276439
          Length = 663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  VSLSFDQ 7
          VSL FDQ
Sbjct: 13 VSLEFDQ 19
>XP_005276438
          Length = 686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  VSLSFDQ 7
          VSL FDQ
Sbjct: 13 VSLEFDQ 19
>XP_006719463
          Length = 390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VSLSFDQ 7
          +SLSFD+
Sbjct: 88 ISLSFDE 94
>XP_006719462
          Length = 430

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VSLSFDQ 7
           +SLSFD+
Sbjct: 128 ISLSFDE 134
>XP_005268929
          Length = 491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VSLSFDQ 7
           +SLSFD+
Sbjct: 189 ISLSFDE 195
>XP_006717918
          Length = 686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  VSLSFDQ 7
          VSL FDQ
Sbjct: 13 VSLEFDQ 19
>XP_006717917
          Length = 686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  VSLSFDQ 7
          VSL FDQ
Sbjct: 13 VSLEFDQ 19
>XP_006717916
          Length = 739

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  VSLSFDQ 7
          VSL FDQ
Sbjct: 66 VSLEFDQ 72
>XP_005269893
          Length = 739

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  VSLSFDQ 7
          VSL FDQ
Sbjct: 66 VSLEFDQ 72
>XP_005271857
          Length = 686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  VSLSFDQ 7
          VSL FDQ
Sbjct: 13 VSLEFDQ 19
>XP_006717684
          Length = 686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  VSLSFDQ 7
          VSL FDQ
Sbjct: 13 VSLEFDQ 19
>XP_006717682
          Length = 716

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  VSLSFDQ 7
          VSL FDQ
Sbjct: 66 VSLEFDQ 72
>XP_005271854
          Length = 739

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  VSLSFDQ 7
          VSL FDQ
Sbjct: 66 VSLEFDQ 72
>XP_006710000
          Length = 137

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  VSLSFDQ 7
          VSL FDQ
Sbjct: 13 VSLEFDQ 19
>NP_001071133
          Length = 686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  VSLSFDQ 7
          VSL FDQ
Sbjct: 13 VSLEFDQ 19
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.141    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 384,467
Number of extensions: 422
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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