Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001073922                                                           18    1935
NP_000258                                                              17    2528
NP_001035957                                                           17    2528
XP_006721991                                                           17    2528
XP_006721990                                                           17    2528
XP_006721989                                                           17    2528
XP_005258041                                                           17    2528
XP_006721988                                                           17    2528
XP_006721987                                                           17    2528
XP_006721986                                                           17    2528
XP_005258040                                                           17    2528
XP_006721985                                                           17    2528
NP_057305                                                              17    3301
XP_005268514                                                           17    3301
NP_001129115                                                           17    3301
NP_001129116                                                           17    3301
NP_001073942                                                           17    4312
XP_005264358                                                           17    4312
NP_079430                                                              16    5631
NP_001124437                                                           16    5631
NP_001269645                                                           16    7355
NP_036579                                                              16    7355
NP_001269646                                                           16    7355
NP_001269647                                                           16    7355
NP_001036216                                                           16    7355
NP_005853                                                              16    7355
NP_001036214                                                           16    7355
NP_006594                                                              16    7355
NP_001036215                                                           16    7355
NP_001269347                                                           16    7355
NP_852111                                                              16    7355
NP_000136                                                              16    7355
NP_001094344                                                           16    7355
NP_631912                                                              16    7355
XP_006724972                                                           16    7355
XP_006724791                                                           16    7355
XP_005262418                                                           16    7355
XP_005262417                                                           16    7355
XP_005262416                                                           16    7355
XP_005262415                                                           16    7355
XP_006724790                                                           16    7355
XP_005262414                                                           16    7355
XP_005250173                                                           16    7355
XP_006714156                                                           16    7355
XP_006714155                                                           16    7355
XP_006713534                                                           16    7355
NP_001193941                                                           15    9605
NP_002623                                                              15    9605
NP_003310                                                              15    9605
NP_597676                                                              15    9605
NP_001243779                                                           15    9605
NP_596869                                                              15    9605
NP_003974                                                              15    9605
NP_001070253                                                           15    9605
NP_699172                                                              15    9605
NP_001120833                                                           15    9605
NP_008931                                                              15    9605
NP_001268372                                                           15    9605
XP_005267818                                                           15    9605
XP_005246888                                                           15    9605
XP_006712788                                                           15    9605
XP_006712787                                                           15    9605
XP_006712786                                                           15    9605
XP_006710421                                                           15    9605
XP_006710420                                                           15    9605
XP_005270517                                                           15    9605
XP_006710419                                                           15    9605
NP_001254479                                                           15    9605
NP_597681                                                              15    9605
>NP_001073922
          Length = 2190

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SLLAGLSL 9
            SLLAGLSL
Sbjct: 2000 SLLAGLSL 2007
>NP_000258
          Length = 2818

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLLAGLSL 9
            VSLLAGL L
Sbjct: 1077 VSLLAGLPL 1085
>NP_001035957
          Length = 2839

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLLAGLSL 9
            VSLLAGL L
Sbjct: 1077 VSLLAGLPL 1085
>XP_006721991
          Length = 1632

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLLAGLSL 9
            VSLLAGL L
Sbjct: 1087 VSLLAGLPL 1095
>XP_006721990
          Length = 2823

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLLAGLSL 9
            VSLLAGL L
Sbjct: 1087 VSLLAGLPL 1095
>XP_006721989
          Length = 2823

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLLAGLSL 9
            VSLLAGL L
Sbjct: 1087 VSLLAGLPL 1095
>XP_005258041
          Length = 2836

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLLAGLSL 9
            VSLLAGL L
Sbjct: 1077 VSLLAGLPL 1085
>XP_006721988
          Length = 2846

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLLAGLSL 9
            VSLLAGL L
Sbjct: 1087 VSLLAGLPL 1095
>XP_006721987
          Length = 2849

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLLAGLSL 9
            VSLLAGL L
Sbjct: 1087 VSLLAGLPL 1095
>XP_006721986
          Length = 2854

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLLAGLSL 9
            VSLLAGL L
Sbjct: 1074 VSLLAGLPL 1082
>XP_005258040
          Length = 2857

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLLAGLSL 9
            VSLLAGL L
Sbjct: 1077 VSLLAGLPL 1085
>XP_006721985
          Length = 2867

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSLLAGLSL 9
            VSLLAGL L
Sbjct: 1087 VSLLAGLPL 1095
>NP_057305
          Length = 460

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSLLAGLSL 9
           +S LAGLSL
Sbjct: 197 ISTLAGLSL 205
>XP_005268514
          Length = 317

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  VSLLAGLSL 9
          +S LAGLSL
Sbjct: 54 ISTLAGLSL 62
>NP_001129115
          Length = 467

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSLLAGLSL 9
           +S LAGLSL
Sbjct: 204 ISTLAGLSL 212
>NP_001129116
          Length = 403

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSLLAGLSL 9
           +S LAGLSL
Sbjct: 140 ISTLAGLSL 148
>NP_001073942
          Length = 497

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSLLAGLSL 9
           +S LAGLSL
Sbjct: 268 LSFLAGLSL 276
>XP_005264358
          Length = 504

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSLLAGLSL 9
           +S LAGLSL
Sbjct: 268 LSFLAGLSL 276
>NP_079430
          Length = 702

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LLAGLSL 9
           LLAGLSL
Sbjct: 219 LLAGLSL 225
>NP_001124437
          Length = 785

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LLAGLSL 9
           LLAGLSL
Sbjct: 302 LLAGLSL 308
>NP_001269645
          Length = 1225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSLLAGLS 8
           +SLL GLS
Sbjct: 217 ISLLTGLS 224
>NP_036579
          Length = 1225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSLLAGLS 8
           +SLL GLS
Sbjct: 217 ISLLTGLS 224
>NP_001269646
          Length = 1226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSLLAGLS 8
           +SLL GLS
Sbjct: 217 ISLLTGLS 224
>NP_001269647
          Length = 1167

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSLLAGLS 8
           +SLL GLS
Sbjct: 159 ISLLTGLS 166
>NP_001036216
          Length = 1231

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSLLAGLS 8
           +SLL GLS
Sbjct: 201 ISLLTGLS 208
>NP_005853
          Length = 1258

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSLLAGLS 8
           +SLL GLS
Sbjct: 204 ISLLTGLS 211
>NP_001036214
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSLLAGLS 8
           +SLL GLS
Sbjct: 201 ISLLTGLS 208
>NP_006594
          Length = 1231

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSLLAGLS 8
           +SLL GLS
Sbjct: 201 ISLLTGLS 208
>NP_001036215
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSLLAGLS 8
           +SLL GLS
Sbjct: 201 ISLLTGLS 208
>NP_001269347
          Length = 1231

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSLLAGLS 8
           +SLL GLS
Sbjct: 201 ISLLTGLS 208
>NP_852111
          Length = 669

 Score = 15.8 bits (29), Expect =  7355
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VSLLAGLSL 9
          VSLLA LSL
Sbjct: 6  VSLLAFLSL 14
>NP_000136
          Length = 695

 Score = 15.8 bits (29), Expect =  7355
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VSLLAGLSL 9
          VSLLA LSL
Sbjct: 6  VSLLAFLSL 14
>NP_001094344
          Length = 475

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSLLAGLSL 9
           +SLLAG+ L
Sbjct: 292 ISLLAGIVL 300
>NP_631912
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSLLAGLSL 9
           +SLLAG+ L
Sbjct: 292 ISLLAGIVL 300
>XP_006724972
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSLLAGLSL 9
           +SLLAG+ L
Sbjct: 224 ISLLAGIVL 232
>XP_006724791
          Length = 1199

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSLLAGLS 8
           +SLL GLS
Sbjct: 132 ISLLTGLS 139
>XP_005262418
          Length = 1231

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSLLAGLS 8
           +SLL GLS
Sbjct: 201 ISLLTGLS 208
>XP_005262417
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSLLAGLS 8
           +SLL GLS
Sbjct: 201 ISLLTGLS 208
>XP_005262416
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSLLAGLS 8
           +SLL GLS
Sbjct: 201 ISLLTGLS 208
>XP_005262415
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSLLAGLS 8
           +SLL GLS
Sbjct: 201 ISLLTGLS 208
>XP_006724790
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSLLAGLS 8
           +SLL GLS
Sbjct: 201 ISLLTGLS 208
>XP_005262414
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSLLAGLS 8
           +SLL GLS
Sbjct: 201 ISLLTGLS 208
>XP_005250173
          Length = 1222

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSLLAGLS 8
           +SLL GLS
Sbjct: 217 ISLLTGLS 224
>XP_006714156
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSLLAGLSL 9
           +SLLAG+ L
Sbjct: 292 ISLLAGIVL 300
>XP_006714155
          Length = 624

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSLLAGLSL 9
           +SLLAG+ L
Sbjct: 401 ISLLAGIVL 409
>XP_006713534
          Length = 1222

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSLLAGLS 8
           +SLL GLS
Sbjct: 204 ISLLTGLS 211
>NP_001193941
          Length = 149

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VSLLAGLSL 9
          + LLAGL+L
Sbjct: 11 LQLLAGLAL 19
>NP_002623
          Length = 170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VSLLAGLSL 9
          + LLAGL+L
Sbjct: 11 LQLLAGLAL 19
>NP_003310
          Length = 26926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VSLLAGLSL 9
            V LLAGL++
Sbjct: 7197 VKLLAGLTV 7205
>NP_597676
          Length = 27051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VSLLAGLSL 9
            V LLAGL++
Sbjct: 7322 VKLLAGLTV 7330
>NP_001243779
          Length = 34350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     VSLLAGLSL 9
             V LLAGL++
Sbjct: 14621 VKLLAGLTV 14629
>NP_596869
          Length = 33423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     VSLLAGLSL 9
             V LLAGL++
Sbjct: 13694 VKLLAGLTV 13702
>NP_003974
          Length = 515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VSLLAGLSL 9
          +SLL G+SL
Sbjct: 45 ISLLNGVSL 53
>NP_001070253
          Length = 515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VSLLAGLSL 9
          +SLL G+SL
Sbjct: 45 ISLLNGVSL 53
>NP_699172
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   VSLLAGLSL 9
           +SL+AG+++
Sbjct: 361 ISLIAGIAI 369
>NP_001120833
          Length = 587

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   VSLLAGLSL 9
           +SL+AG+++
Sbjct: 360 ISLIAGIAI 368
>NP_008931
          Length = 258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VSLLAGLSL 9
          + LL+GLSL
Sbjct: 26 IILLSGLSL 34
>NP_001268372
          Length = 273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VSLLAGLSL 9
          + LL+GLSL
Sbjct: 26 IILLSGLSL 34
>XP_005267818
          Length = 169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VSLLAGLSL 9
          + LLAGL+L
Sbjct: 11 LQLLAGLAL 19
>XP_005246888
          Length = 22663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VSLLAGLSL 9
            V LLAGL++
Sbjct: 2934 VKLLAGLTV 2942
>XP_006712788
          Length = 24022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VSLLAGLSL 9
            V LLAGL++
Sbjct: 4293 VKLLAGLTV 4301
>XP_006712787
          Length = 33978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     VSLLAGLSL 9
             V LLAGL++
Sbjct: 14249 VKLLAGLTV 14257
>XP_006712786
          Length = 35484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     VSLLAGLSL 9
             V LLAGL++
Sbjct: 15755 VKLLAGLTV 15763
>XP_006710421
          Length = 588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   VSLLAGLSL 9
           +SL+AG+++
Sbjct: 361 ISLIAGIAI 369
>XP_006710420
          Length = 688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   VSLLAGLSL 9
           +SL+AG+++
Sbjct: 361 ISLIAGIAI 369
>XP_005270517
          Length = 731

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   VSLLAGLSL 9
           +SL+AG+++
Sbjct: 360 ISLIAGIAI 368
>XP_006710419
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   VSLLAGLSL 9
           +SL+AG+++
Sbjct: 361 ISLIAGIAI 369
>NP_001254479
          Length = 35991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     VSLLAGLSL 9
             V LLAGL++
Sbjct: 16262 VKLLAGLTV 16270
>NP_597681
          Length = 27118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VSLLAGLSL 9
            V LLAGL++
Sbjct: 7389 VKLLAGLTV 7397
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.139    0.331 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 366,514
Number of extensions: 582
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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