Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              18    1482
XP_006718908                                                           18    1482
XP_005271621                                                           18    1482
XP_006718907                                                           18    1482
XP_006718906                                                           18    1482
XP_005271619                                                           18    1482
XP_005271618                                                           18    1482
NP_710159                                                              17    2528
XP_005273485                                                           17    2528
NP_919424                                                              17    3301
NP_002287                                                              17    3301
XP_005273182                                                           17    3301
NP_001182192                                                           17    4312
NP_079171                                                              17    4312
XP_006718038                                                           17    4312
XP_005270222                                                           17    4312
NP_006197                                                              16    5631
NP_001231118                                                           16    5631
NP_001231121                                                           16    5631
NP_055564                                                              16    5631
NP_001231119                                                           16    5631
NP_001231120                                                           16    5631
NP_001231122                                                           16    5631
NP_058132                                                              16    5631
NP_001027581                                                           16    5631
XP_006720406                                                           16    5631
XP_006720405                                                           16    5631
XP_006720404                                                           16    5631
XP_006720403                                                           16    5631
XP_006720402                                                           16    5631
XP_006720401                                                           16    5631
XP_006720400                                                           16    5631
XP_006720399                                                           16    5631
XP_006719497                                                           16    5631
XP_006714104                                                           16    5631
XP_005265800                                                           16    5631
XP_006714103                                                           16    5631
XP_006714102                                                           16    5631
NP_002525                                                              16    5631
NP_057336                                                              16    7355
NP_001073932                                                           16    7355
NP_001368                                                              16    7355
XP_006718966                                                           16    7355
XP_006712120                                                           16    7355
XP_005264512                                                           16    7355
XP_005264511                                                           16    7355
XP_006712119                                                           16    7355
XP_005264510                                                           16    7355
XP_006712118                                                           16    7355
XP_005264509                                                           16    7355
XP_005264508                                                           16    7355
XP_006712117                                                           16    7355
XP_005264507                                                           16    7355
XP_005264506                                                           16    7355
NP_060066                                                              15    9605
NP_001239029                                                           15    9605
NP_001239032                                                           15    9605
NP_001239031                                                           15    9605
>NP_000042
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSKVVEGTS 9
            VSK VEGTS
Sbjct: 2115 VSKEVEGTS 2123
>XP_006718908
          Length = 1708

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VSKVVEGTS 9
           VSK VEGTS
Sbjct: 767 VSKEVEGTS 775
>XP_005271621
          Length = 2708

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSKVVEGTS 9
            VSK VEGTS
Sbjct: 1767 VSKEVEGTS 1775
>XP_006718907
          Length = 3050

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSKVVEGTS 9
            VSK VEGTS
Sbjct: 2109 VSKEVEGTS 2117
>XP_006718906
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSKVVEGTS 9
            VSK VEGTS
Sbjct: 2115 VSKEVEGTS 2123
>XP_005271619
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSKVVEGTS 9
            VSK VEGTS
Sbjct: 2115 VSKEVEGTS 2123
>XP_005271618
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSKVVEGTS 9
            VSK VEGTS
Sbjct: 2115 VSKEVEGTS 2123
>NP_710159
          Length = 476

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSKVVEGTS 9
           V KVVEGT+
Sbjct: 412 VCKVVEGTA 420
>XP_005273485
          Length = 464

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSKVVEGTS 9
           V KVVEGT+
Sbjct: 400 VCKVVEGTA 408
>NP_919424
          Length = 615

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSKVVEGT 8
           + KVVEGT
Sbjct: 277 IGKVVEGT 284
>NP_002287
          Length = 615

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSKVVEGT 8
           + KVVEGT
Sbjct: 277 IGKVVEGT 284
>XP_005273182
          Length = 573

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSKVVEGT 8
           + KVVEGT
Sbjct: 277 IGKVVEGT 284
>NP_001182192
          Length = 1033

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSKVVEGTS 9
           VSKV EG+S
Sbjct: 113 VSKVEEGSS 121
>NP_079171
          Length = 517

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSKVVEGTS 9
           VSKV EG+S
Sbjct: 113 VSKVEEGSS 121
>XP_006718038
          Length = 537

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSKVVEGTS 9
           VSKV EG+S
Sbjct: 113 VSKVEEGSS 121
>XP_005270222
          Length = 561

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSKVVEGTS 9
           VSKV EG+S
Sbjct: 113 VSKVEEGSS 121
>NP_006197
          Length = 1089

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KVVEGTS 9
           KVVEGT+
Sbjct: 606 KVVEGTA 612
>NP_001231118
          Length = 1644

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SKVVEGTS 9
            S +VEGTS
Sbjct: 1032 SDIVEGTS 1039
>NP_001231121
          Length = 1504

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKVVEGTS 9
           S +VEGTS
Sbjct: 935 SDIVEGTS 942
>NP_055564
          Length = 1472

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKVVEGTS 9
           S +VEGTS
Sbjct: 903 SDIVEGTS 910
>NP_001231119
          Length = 1533

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKVVEGTS 9
           S +VEGTS
Sbjct: 964 SDIVEGTS 971
>NP_001231120
          Length = 1463

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKVVEGTS 9
           S +VEGTS
Sbjct: 894 SDIVEGTS 901
>NP_001231122
          Length = 1347

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKVVEGTS 9
           S +VEGTS
Sbjct: 839 SDIVEGTS 846
>NP_058132
          Length = 400

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  VSKVVEGTS 9
          VSKVV+G S
Sbjct: 55 VSKVVKGGS 63
>NP_001027581
          Length = 414

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  VSKVVEGTS 9
          VSKVV+G S
Sbjct: 55 VSKVVKGGS 63
>XP_006720406
          Length = 1591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKVVEGTS 9
           S +VEGTS
Sbjct: 979 SDIVEGTS 986
>XP_006720405
          Length = 1347

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKVVEGTS 9
           S +VEGTS
Sbjct: 979 SDIVEGTS 986
>XP_006720404
          Length = 1477

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKVVEGTS 9
           S +VEGTS
Sbjct: 979 SDIVEGTS 986
>XP_006720403
          Length = 1486

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKVVEGTS 9
           S +VEGTS
Sbjct: 979 SDIVEGTS 986
>XP_006720402
          Length = 1487

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKVVEGTS 9
           S +VEGTS
Sbjct: 979 SDIVEGTS 986
>XP_006720401
          Length = 1504

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKVVEGTS 9
           S +VEGTS
Sbjct: 979 SDIVEGTS 986
>XP_006720400
          Length = 1526

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKVVEGTS 9
           S +VEGTS
Sbjct: 979 SDIVEGTS 986
>XP_006720399
          Length = 1548

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKVVEGTS 9
           S +VEGTS
Sbjct: 979 SDIVEGTS 986
>XP_006719497
          Length = 384

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  VSKVVEGTS 9
          VSKVV+G S
Sbjct: 55 VSKVVKGGS 63
>XP_006714104
          Length = 832

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KVVEGTS 9
           KVVEGT+
Sbjct: 631 KVVEGTA 637
>XP_005265800
          Length = 1089

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KVVEGTS 9
           KVVEGT+
Sbjct: 606 KVVEGTA 612
>XP_006714103
          Length = 1111

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KVVEGTS 9
           KVVEGT+
Sbjct: 628 KVVEGTA 634
>XP_006714102
          Length = 1114

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KVVEGTS 9
           KVVEGT+
Sbjct: 631 KVVEGTA 637
>NP_002525
          Length = 364

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  VSKVVEGTS 9
          VSKVV+G S
Sbjct: 55 VSKVVKGGS 63
>NP_057336
          Length = 4857

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KVVEGTS 9
          KV++GTS
Sbjct: 92 KVIDGTS 98
>NP_001073932
          Length = 4314

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VSKVVEGTS 9
            +SKV+ GT+
Sbjct: 4104 LSKVIRGTT 4112
>NP_001368
          Length = 4307

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VSKVVEGTS 9
            +SKV+ GT+
Sbjct: 4097 LSKVIRGTT 4105
>XP_006718966
          Length = 4300

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VSKVVEGTS 9
            +SKV+ GT+
Sbjct: 4090 LSKVIRGTT 4098
>XP_006712120
          Length = 4812

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KVVEGTS 9
          KV++GTS
Sbjct: 92 KVIDGTS 98
>XP_005264512
          Length = 4840

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KVVEGTS 9
          KV++GTS
Sbjct: 92 KVIDGTS 98
>XP_005264511
          Length = 4847

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KVVEGTS 9
          KV++GTS
Sbjct: 92 KVIDGTS 98
>XP_006712119
          Length = 4851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KVVEGTS 9
          KV++GTS
Sbjct: 92 KVIDGTS 98
>XP_005264510
          Length = 4861

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KVVEGTS 9
          KV++GTS
Sbjct: 92 KVIDGTS 98
>XP_006712118
          Length = 4864

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KVVEGTS 9
          KV++GTS
Sbjct: 92 KVIDGTS 98
>XP_005264509
          Length = 4870

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KVVEGTS 9
          KV++GTS
Sbjct: 92 KVIDGTS 98
>XP_005264508
          Length = 4875

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KVVEGTS 9
          KV++GTS
Sbjct: 92 KVIDGTS 98
>XP_006712117
          Length = 4878

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KVVEGTS 9
          KV++GTS
Sbjct: 92 KVIDGTS 98
>XP_005264507
          Length = 4880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KVVEGTS 9
          KV++GTS
Sbjct: 92 KVIDGTS 98
>XP_005264506
          Length = 4884

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KVVEGTS 9
          KV++GTS
Sbjct: 92 KVIDGTS 98
>NP_060066
          Length = 1624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VSKVVEG 7
          VSK++EG
Sbjct: 68 VSKLIEG 74
>NP_001239029
          Length = 1637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VSKVVEG 7
          VSK++EG
Sbjct: 68 VSKLIEG 74
>NP_001239032
          Length = 1610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VSKVVEG 7
          VSK++EG
Sbjct: 68 VSKLIEG 74
>NP_001239031
          Length = 1623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VSKVVEG 7
          VSK++EG
Sbjct: 68 VSKLIEG 74
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.293    0.113    0.259 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 442,341
Number of extensions: 425
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package