Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              18    1482
NP_001075109                                                           18    1482
NP_065783                                                              17    3301
NP_059989                                                              17    3301
XP_006715590                                                           17    3301
XP_005267126                                                           17    3301
XP_006715589                                                           17    3301
XP_006715588                                                           17    3301
XP_006715587                                                           17    3301
XP_006715586                                                           17    3301
NP_036374                                                              17    4312
NP_001005190                                                           16    5631
NP_001123481                                                           16    7355
NP_872431                                                              16    7355
XP_006714629                                                           16    7355
XP_006712069                                                           16    7355
XP_006712068                                                           16    7355
XP_005262670                                                           16    7355
NP_001026                                                              15    9605
XP_006725534                                                           15    9605
XP_006711873                                                           15    9605
XP_006711871                                                           15    9605
XP_006711870                                                           15    9605
XP_006711869                                                           15    9605
XP_006711868                                                           15    9605
XP_006711867                                                           15    9605
XP_006711866                                                           15    9605
XP_006711865                                                           15    9605
NP_443155                                                              15    9605
>NP_008835
          Length = 4128

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSAVLNSML 9
            VSAVLN ML
Sbjct: 1593 VSAVLNGML 1601
>NP_001075109
          Length = 4097

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSAVLNSML 9
            VSAVLN ML
Sbjct: 1593 VSAVLNGML 1601
>NP_065783
          Length = 2249

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    VSAVLNSML 9
            +SAVLNS++
Sbjct: 2227 ISAVLNSLV 2235
>NP_059989
          Length = 2236

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    VSAVLNSML 9
            +SAVLNS++
Sbjct: 2214 ISAVLNSLV 2222
>XP_006715590
          Length = 2277

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    VSAVLNSML 9
            +SAVLNS++
Sbjct: 2255 ISAVLNSLV 2263
>XP_005267126
          Length = 2316

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    VSAVLNSML 9
            +SAVLNS++
Sbjct: 2294 ISAVLNSLV 2302
>XP_006715589
          Length = 2320

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    VSAVLNSML 9
            +SAVLNS++
Sbjct: 2298 ISAVLNSLV 2306
>XP_006715588
          Length = 2330

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    VSAVLNSML 9
            +SAVLNS++
Sbjct: 2308 ISAVLNSLV 2316
>XP_006715587
          Length = 2359

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    VSAVLNSML 9
            +SAVLNS++
Sbjct: 2337 ISAVLNSLV 2345
>XP_006715586
          Length = 2373

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    VSAVLNSML 9
            +SAVLNS++
Sbjct: 2351 ISAVLNSLV 2359
>NP_036374
          Length = 266

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  VSAVLNSML 9
          VSA LNS+L
Sbjct: 29 VSATLNSVL 37
>NP_001005190
          Length = 309

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSAVLNSML 9
           + +VLNSML
Sbjct: 150 IMSVLNSML 158
>NP_001123481
          Length = 908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSAVLNSML 9
           +SA LNS+L
Sbjct: 522 ISASLNSLL 530
>NP_872431
          Length = 908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSAVLNSML 9
           +SA LNS+L
Sbjct: 522 ISASLNSLL 530
>XP_006714629
          Length = 409

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  SAVLNSML 9
          SAVLN+M+
Sbjct: 31 SAVLNAMV 38
>XP_006712069
          Length = 908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSAVLNSML 9
           +SA LNS+L
Sbjct: 522 ISASLNSLL 530
>XP_006712068
          Length = 908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSAVLNSML 9
           +SA LNS+L
Sbjct: 522 ISASLNSLL 530
>XP_005262670
          Length = 908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSAVLNSML 9
           +SA LNS+L
Sbjct: 522 ISASLNSLL 530
>NP_001026
          Length = 4967

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    VSAVLNSM 8
            +SAVLNS+
Sbjct: 4694 LSAVLNSI 4701
>XP_006725534
          Length = 1174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSAVLNSML 9
           +SA LNS+L
Sbjct: 860 ISAELNSVL 868
>XP_006711873
          Length = 4954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    VSAVLNSM 8
            +SAVLNS+
Sbjct: 4681 LSAVLNSI 4688
>XP_006711871
          Length = 4906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    VSAVLNSM 8
            +SAVLNS+
Sbjct: 4633 LSAVLNSI 4640
>XP_006711870
          Length = 4965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    VSAVLNSM 8
            +SAVLNS+
Sbjct: 4692 LSAVLNSI 4699
>XP_006711869
          Length = 4973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    VSAVLNSM 8
            +SAVLNS+
Sbjct: 4700 LSAVLNSI 4707
>XP_006711868
          Length = 4975

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    VSAVLNSM 8
            +SAVLNS+
Sbjct: 4702 LSAVLNSI 4709
>XP_006711867
          Length = 4977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    VSAVLNSM 8
            +SAVLNS+
Sbjct: 4704 LSAVLNSI 4711
>XP_006711866
          Length = 4984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    VSAVLNSM 8
            +SAVLNS+
Sbjct: 4711 LSAVLNSI 4718
>XP_006711865
          Length = 4985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    VSAVLNSM 8
            +SAVLNS+
Sbjct: 4712 LSAVLNSI 4719
>NP_443155
          Length = 1325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VSAVLNSML 9
            +SA LNS+L
Sbjct: 1011 ISAELNSVL 1019
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.122    0.274 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 260,160
Number of extensions: 152
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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