Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115927                                                              19     665
NP_653223                                                              17    2528
NP_065813                                                              16    7355
NP_001121190                                                           16    7355
NP_001121189                                                           16    7355
NP_001186017                                                           16    7355
NP_001186016                                                           16    7355
NP_001002006                                                           16    7355
NP_001186033                                                           16    7355
NP_001180308                                                           16    7355
NP_001070254                                                           16    7355
NP_060329                                                              16    7355
XP_006723876                                                           16    7355
XP_006723875                                                           16    7355
XP_006723874                                                           16    7355
XP_006723873                                                           16    7355
XP_006723872                                                           16    7355
XP_005260273                                                           16    7355
XP_006723871                                                           16    7355
XP_006723870                                                           16    7355
XP_006723869                                                           16    7355
XP_005269099                                                           16    7355
XP_006718388                                                           16    7355
XP_006718387                                                           16    7355
XP_006718386                                                           16    7355
NP_001229825                                                           15    9605
NP_001229826                                                           15    9605
NP_653319                                                              15    9605
NP_060050                                                              15    9605
NP_055477                                                              15    9605
NP_001129501                                                           15    9605
NP_619520                                                              15    9605
NP_055781                                                              15    9605
NP_006276                                                              15    9605
XP_005261924                                                           15    9605
XP_006724450                                                           15    9605
XP_006724449                                                           15    9605
XP_005261923                                                           15    9605
XP_006724448                                                           15    9605
XP_006724447                                                           15    9605
XP_005261922                                                           15    9605
XP_005261921                                                           15    9605
XP_005261920                                                           15    9605
XP_005261919                                                           15    9605
XP_005269983                                                           15    9605
XP_005269982                                                           15    9605
XP_006717970                                                           15    9605
XP_006714215                                                           15    9605
XP_006714214                                                           15    9605
XP_005262915                                                           15    9605
XP_006713578                                                           15    9605
XP_006713096                                                           15    9605
XP_006713095                                                           15    9605
NP_055806                                                              15    9605
>NP_115927
          Length = 1321

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   RLLNRVRR 9
           RLLNRVRR
Sbjct: 700 RLLNRVRR 707
>NP_653223
          Length = 773

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VRLLNRVRR 9
           ++LLNRVR+
Sbjct: 271 IQLLNRVRQ 279
>NP_065813
          Length = 1085

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LLNRVRR 9
           LLN+VRR
Sbjct: 103 LLNQVRR 109
>NP_001121190
          Length = 1668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VRLLNRVR 8
           V +LNR+R
Sbjct: 335 VHMLNRIR 342
>NP_001121189
          Length = 3277

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VRLLNRVR 8
            V +LNR+R
Sbjct: 1944 VHMLNRIR 1951
>NP_001186017
          Length = 612

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VRLLNRVRR 9
          VRL N++RR
Sbjct: 35 VRLSNQMRR 43
>NP_001186016
          Length = 627

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VRLLNRVRR 9
          VRL N++RR
Sbjct: 35 VRLSNQMRR 43
>NP_001002006
          Length = 610

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VRLLNRVRR 9
          VRL N++RR
Sbjct: 35 VRLSNQMRR 43
>NP_001186033
          Length = 602

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VRLLNRVRR 9
          VRL N++RR
Sbjct: 35 VRLSNQMRR 43
>NP_001180308
          Length = 533

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VRLLNRVRR 9
           +RL+ R+RR
Sbjct: 217 IRLVRRLRR 225
>NP_001070254
          Length = 1735

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VRLLNRVRR 9
            VR+ NR RR
Sbjct: 1170 VRMPNRTRR 1178
>NP_060329
          Length = 548

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VRLLNRVRR 9
           +RL+ R+RR
Sbjct: 232 IRLVRRLRR 240
>XP_006723876
          Length = 432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VRLLNRVRR 9
           +RL+ R+RR
Sbjct: 116 IRLVRRLRR 124
>XP_006723875
          Length = 442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VRLLNRVRR 9
           +RL+ R+RR
Sbjct: 124 IRLVRRLRR 132
>XP_006723874
          Length = 542

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VRLLNRVRR 9
           +RL+ R+RR
Sbjct: 224 IRLVRRLRR 232
>XP_006723873
          Length = 549

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VRLLNRVRR 9
           +RL+ R+RR
Sbjct: 231 IRLVRRLRR 239
>XP_006723872
          Length = 550

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VRLLNRVRR 9
           +RL+ R+RR
Sbjct: 232 IRLVRRLRR 240
>XP_005260273
          Length = 556

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VRLLNRVRR 9
           +RL+ R+RR
Sbjct: 240 IRLVRRLRR 248
>XP_006723871
          Length = 557

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VRLLNRVRR 9
           +RL+ R+RR
Sbjct: 239 IRLVRRLRR 247
>XP_006723870
          Length = 557

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VRLLNRVRR 9
           +RL+ R+RR
Sbjct: 240 IRLVRRLRR 248
>XP_006723869
          Length = 558

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VRLLNRVRR 9
           +RL+ R+RR
Sbjct: 240 IRLVRRLRR 248
>XP_005269099
          Length = 1062

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LLNRVRR 9
           LLN+VRR
Sbjct: 103 LLNQVRR 109
>XP_006718388
          Length = 1331

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VRLLNRVRR 9
            VR+ NR RR
Sbjct: 1233 VRMPNRTRR 1241
>XP_006718387
          Length = 1798

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VRLLNRVRR 9
            VR+ NR RR
Sbjct: 1233 VRMPNRTRR 1241
>XP_006718386
          Length = 1822

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VRLLNRVRR 9
            VR+ NR RR
Sbjct: 1233 VRMPNRTRR 1241
>NP_001229825
          Length = 1603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LNRVRR 9
           LNR+RR
Sbjct: 993 LNRIRR 998
>NP_001229826
          Length = 1503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LNRVRR 9
           LNR+RR
Sbjct: 915 LNRIRR 920
>NP_653319
          Length = 855

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RLLNRVRR 9
           +LLN+V+R
Sbjct: 292 QLLNKVKR 299
>NP_060050
          Length = 708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VRLLNR 6
           VRLLNR
Sbjct: 300 VRLLNR 305
>NP_055477
          Length = 1572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LNRVRR 9
           LNR+RR
Sbjct: 984 LNRIRR 989
>NP_001129501
          Length = 1594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LNRVRR 9
           LNR+RR
Sbjct: 984 LNRIRR 989
>NP_619520
          Length = 1194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VRLLNRVRR 9
            VRLL  +RR
Sbjct: 1135 VRLLKELRR 1143
>NP_055781
          Length = 1155

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VRLLNRVRR 9
            VRLL  +RR
Sbjct: 1096 VRLLKELRR 1104
>NP_006276
          Length = 626

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VRLLNRVR 8
           V+L+NR+R
Sbjct: 101 VQLMNRLR 108
>XP_005261924
          Length = 1176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LNRVRR 9
           LNR+RR
Sbjct: 993 LNRIRR 998
>XP_006724450
          Length = 1187

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LNRVRR 9
           LNR+RR
Sbjct: 993 LNRIRR 998
>XP_006724449
          Length = 1198

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LNRVRR 9
           LNR+RR
Sbjct: 993 LNRIRR 998
>XP_005261923
          Length = 1307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LNRVRR 9
           LNR+RR
Sbjct: 993 LNRIRR 998
>XP_006724448
          Length = 1490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LNRVRR 9
           LNR+RR
Sbjct: 880 LNRIRR 885
>XP_006724447
          Length = 1516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LNRVRR 9
           LNR+RR
Sbjct: 906 LNRIRR 911
>XP_005261922
          Length = 1525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LNRVRR 9
           LNR+RR
Sbjct: 915 LNRIRR 920
>XP_005261921
          Length = 1581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LNRVRR 9
           LNR+RR
Sbjct: 993 LNRIRR 998
>XP_005261920
          Length = 1594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LNRVRR 9
           LNR+RR
Sbjct: 984 LNRIRR 989
>XP_005261919
          Length = 1603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LNRVRR 9
           LNR+RR
Sbjct: 993 LNRIRR 998
>XP_005269983
          Length = 708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VRLLNR 6
           VRLLNR
Sbjct: 300 VRLLNR 305
>XP_005269982
          Length = 734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VRLLNR 6
           VRLLNR
Sbjct: 326 VRLLNR 331
>XP_006717970
          Length = 734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VRLLNR 6
           VRLLNR
Sbjct: 326 VRLLNR 331
>XP_006714215
          Length = 3544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    VRLLNRVRR 9
            VRLL  VRR
Sbjct: 1138 VRLLTVVRR 1146
>XP_006714214
          Length = 3544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    VRLLNRVRR 9
            VRLL  VRR
Sbjct: 1138 VRLLTVVRR 1146
>XP_005262915
          Length = 3544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    VRLLNRVRR 9
            VRLL  VRR
Sbjct: 1138 VRLLTVVRR 1146
>XP_006713578
          Length = 855

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RLLNRVRR 9
           +LLN+V+R
Sbjct: 292 QLLNKVKR 299
>XP_006713096
          Length = 1162

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VRLLNRVRR 9
            VRLL  +RR
Sbjct: 1103 VRLLKELRR 1111
>XP_006713095
          Length = 1222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VRLLNRVRR 9
            VRLL  +RR
Sbjct: 1163 VRLLKELRR 1171
>NP_055806
          Length = 3526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    VRLLNRVRR 9
            VRLL  VRR
Sbjct: 1120 VRLLTVVRR 1128
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.350    0.157    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 347,686
Number of extensions: 568
Number of successful extensions: 54
Number of sequences better than 10000.0: 54
Number of HSP's gapped: 54
Number of HSP's successfully gapped: 54
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.8 bits)
S2: 28 (15.4 bits)

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