Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_005268734                                                           16    7355
NP_689653                                                              16    7355
NP_057332                                                              15    9605
XP_005266307                                                           15    9605
XP_005266306                                                           15    9605
XP_005266305                                                           15    9605
XP_005266304                                                           15    9605
>XP_005268734
          Length = 468

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSQRAVQ 8
           QSQ+AVQ
Sbjct: 244 QSQKAVQ 250
>NP_689653
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSQRAVQ 8
           QSQ+AVQ
Sbjct: 244 QSQKAVQ 250
>NP_057332
          Length = 1901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VQSQRAV 7
            VQSQR+V
Sbjct: 1235 VQSQRSV 1241
>XP_005266307
          Length = 1796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VQSQRAV 7
            VQSQR+V
Sbjct: 1235 VQSQRSV 1241
>XP_005266306
          Length = 1824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VQSQRAV 7
            VQSQR+V
Sbjct: 1235 VQSQRSV 1241
>XP_005266305
          Length = 1856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VQSQRAV 7
            VQSQR+V
Sbjct: 1190 VQSQRSV 1196
>XP_005266304
          Length = 1873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VQSQRAV 7
            VQSQR+V
Sbjct: 1235 VQSQRSV 1241
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.120    0.270 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 221,627
Number of extensions: 142
Number of successful extensions: 7
Number of sequences better than 10000.0: 7
Number of HSP's gapped: 7
Number of HSP's successfully gapped: 7
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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