Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           19     869
NP_000242                                                              19     869
XP_005264389                                                           19     869
NP_055238                                                              17    3301
XP_005272021                                                           17    3301
XP_006714650                                                           17    3301
XP_005272020                                                           17    3301
NP_001078896                                                           16    5631
NP_001078894                                                           16    5631
NP_001078897                                                           16    5631
NP_000478                                                              16    5631
NP_001078895                                                           16    5631
NP_001074025                                                           16    5631
XP_006724477                                                           16    5631
NP_659491                                                              16    5631
NP_001129575                                                           15    9605
NP_005467                                                              15    9605
NP_001177312                                                           15    9605
NP_001177317                                                           15    9605
NP_001121699                                                           15    9605
NP_001287                                                              15    9605
>NP_001245210
          Length = 868

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   QLDAVVSF 9
           QLDAVVSF
Sbjct: 535 QLDAVVSF 542
>NP_000242
          Length = 934

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   QLDAVVSF 9
           QLDAVVSF
Sbjct: 601 QLDAVVSF 608
>XP_005264389
          Length = 921

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   QLDAVVSF 9
           QLDAVVSF
Sbjct: 601 QLDAVVSF 608
>NP_055238
          Length = 1163

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LDAVVSF 9
           LDAVVSF
Sbjct: 943 LDAVVSF 949
>XP_005272021
          Length = 785

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LDAVVSF 9
           LDAVVSF
Sbjct: 565 LDAVVSF 571
>XP_006714650
          Length = 1134

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LDAVVSF 9
           LDAVVSF
Sbjct: 914 LDAVVSF 920
>XP_005272020
          Length = 1163

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LDAVVSF 9
           LDAVVSF
Sbjct: 943 LDAVVSF 949
>NP_001078896
          Length = 509

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLDAVVSF 9
           QLDA V+F
Sbjct: 467 QLDAAVTF 474
>NP_001078894
          Length = 509

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLDAVVSF 9
           QLDA V+F
Sbjct: 467 QLDAAVTF 474
>NP_001078897
          Length = 423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLDAVVSF 9
           QLDA V+F
Sbjct: 381 QLDAAVTF 388
>NP_000478
          Length = 509

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLDAVVSF 9
           QLDA V+F
Sbjct: 467 QLDAAVTF 474
>NP_001078895
          Length = 509

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLDAVVSF 9
           QLDA V+F
Sbjct: 467 QLDAAVTF 474
>NP_001074025
          Length = 552

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VQLDAVVSF 9
          ++LDAV+ F
Sbjct: 14 LELDAVIGF 22
>XP_006724477
          Length = 488

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLDAVVSF 9
           QLDA V+F
Sbjct: 446 QLDAAVTF 453
>NP_659491
          Length = 620

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VQLDAVVSF 9
          ++LDAV+ F
Sbjct: 14 LELDAVIGF 22
>NP_001129575
          Length = 1108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QLDAVVSF 9
           ++DAVV+F
Sbjct: 501 KMDAVVNF 508
>NP_005467
          Length = 722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LDAVVSF 9
           LDA++SF
Sbjct: 237 LDALISF 243
>NP_001177312
          Length = 648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LDAVVSF 9
           LDA++SF
Sbjct: 237 LDALISF 243
>NP_001177317
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LDAVVSF 9
           LDA++SF
Sbjct: 232 LDALISF 238
>NP_001121699
          Length = 753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LDAVVSF 9
           LDA++SF
Sbjct: 268 LDALISF 274
>NP_001287
          Length = 384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  DAVVSF 9
          DAVVSF
Sbjct: 39 DAVVSF 44
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.139    0.352 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 309,314
Number of extensions: 359
Number of successful extensions: 21
Number of sequences better than 10000.0: 21
Number of HSP's gapped: 21
Number of HSP's successfully gapped: 21
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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