Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_056046                                                              17    2528
XP_006718233                                                           17    2528
XP_005272458                                                           17    2528
XP_006716327                                                           17    2528
NP_699163                                                              17    2528
NP_115272                                                              17    4312
NP_061750                                                              17    4312
NP_004477                                                              17    4312
XP_005251989                                                           17    4312
XP_005251988                                                           17    4312
XP_005251987                                                           17    4312
NP_037386                                                              16    5631
NP_116207                                                              16    5631
XP_005268867                                                           16    5631
XP_005268866                                                           16    5631
NP_001257903                                                           16    7355
NP_996766                                                              16    7355
NP_945350                                                              16    7355
NP_001161434                                                           16    7355
NP_996767                                                              16    7355
NP_056127                                                              16    7355
NP_057340                                                              16    7355
XP_006721269                                                           16    7355
XP_006716039                                                           16    7355
XP_006716038                                                           16    7355
XP_006714407                                                           16    7355
XP_006714405                                                           16    7355
XP_005263349                                                           16    7355
XP_005263348                                                           16    7355
XP_005263347                                                           16    7355
XP_005263346                                                           16    7355
XP_005263345                                                           16    7355
XP_005263344                                                           16    7355
XP_005263343                                                           16    7355
XP_005263342                                                           16    7355
XP_005263341                                                           16    7355
XP_005263340                                                           16    7355
XP_005263339                                                           16    7355
NP_005742                                                              15    9605
NP_671714                                                              15    9605
NP_689969                                                              15    9605
NP_001272368                                                           15    9605
NP_060318                                                              15    9605
NP_064716                                                              15    9605
NP_660352                                                              15    9605
NP_001192067                                                           15    9605
NP_599025                                                              15    9605
NP_006513                                                              15    9605
NP_001035544                                                           15    9605
NP_001268662                                                           15    9605
NP_075062                                                              15    9605
NP_001268661                                                           15    9605
XP_006718537                                                           15    9605
XP_006718536                                                           15    9605
XP_006718535                                                           15    9605
XP_006715890                                                           15    9605
XP_005250160                                                           15    9605
XP_005250159                                                           15    9605
XP_006714526                                                           15    9605
NP_602298                                                              15    9605
NP_036283                                                              15    9605
NP_001007525                                                           15    9605
NP_001007524                                                           15    9605
>NP_056046
          Length = 1436

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QCSLSRVR 9
            +CSL+R+R
Sbjct: 1186 ECSLARIR 1193
>XP_006718233
          Length = 782

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QCSLSRVR 9
           +CSL+R+R
Sbjct: 532 ECSLARIR 539
>XP_005272458
          Length = 271

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VQCSLSRVR 9
           +QC LSR++
Sbjct: 163 IQCQLSRLK 171
>XP_006716327
          Length = 349

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VQCSLSRVR 9
           +QC LSR++
Sbjct: 241 IQCQLSRLK 249
>NP_699163
          Length = 349

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VQCSLSRVR 9
           +QC LSR++
Sbjct: 241 IQCQLSRLK 249
>NP_115272
          Length = 808

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VQCSLSR 7
           V+CSLSR
Sbjct: 382 VRCSLSR 388
>NP_061750
          Length = 929

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VQCSLSR 7
           V+CSLSR
Sbjct: 382 VRCSLSR 388
>NP_004477
          Length = 1002

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QCSLSRVR 9
           +CS+SRV+
Sbjct: 426 ECSMSRVQ 433
>XP_005251989
          Length = 975

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QCSLSRVR 9
           +CS+SRV+
Sbjct: 399 ECSMSRVQ 406
>XP_005251988
          Length = 1002

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QCSLSRVR 9
           +CS+SRV+
Sbjct: 426 ECSMSRVQ 433
>XP_005251987
          Length = 1029

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QCSLSRVR 9
           +CS+SRV+
Sbjct: 453 ECSMSRVQ 460
>NP_037386
          Length = 729

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VQCSLSR 7
           V CSLSR
Sbjct: 265 VSCSLSR 271
>NP_116207
          Length = 335

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   QCSLSRV 8
           QC LSRV
Sbjct: 282 QCHLSRV 288
>XP_005268867
          Length = 729

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VQCSLSR 7
           V CSLSR
Sbjct: 265 VSCSLSR 271
>XP_005268866
          Length = 729

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VQCSLSR 7
           V CSLSR
Sbjct: 265 VSCSLSR 271
>NP_001257903
          Length = 5121

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1    VQCSLSRV 8
            ++C LSR+
Sbjct: 3726 IRCKLSRI 3733
>NP_996766
          Length = 685

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VQCSLSR 7
           + CSLSR
Sbjct: 393 ISCSLSR 399
>NP_945350
          Length = 744

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VQCSLSR 7
           + CSLSR
Sbjct: 393 ISCSLSR 399
>NP_001161434
          Length = 712

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VQCSLSR 7
           + CSLSR
Sbjct: 393 ISCSLSR 399
>NP_996767
          Length = 516

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VQCSLSR 7
           + CSLSR
Sbjct: 393 ISCSLSR 399
>NP_056127
          Length = 5005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VQCSLSRVR 9
            V+ SLSR+R
Sbjct: 4208 VKVSLSRIR 4216
>NP_057340
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   CSLSRVR 9
           CS+SRV+
Sbjct: 421 CSVSRVK 427
>XP_006721269
          Length = 5138

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1    VQCSLSRV 8
            ++C LSR+
Sbjct: 3743 IRCKLSRI 3750
>XP_006716039
          Length = 505

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VQCSLSR 7
           + CSLSR
Sbjct: 393 ISCSLSR 399
>XP_006716038
          Length = 239

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VQCSLSR 7
           + CSLSR
Sbjct: 127 ISCSLSR 133
>XP_006714407
          Length = 5004

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VQCSLSRVR 9
            V+ SLSR+R
Sbjct: 4207 VKVSLSRIR 4215
>XP_006714405
          Length = 4103

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VQCSLSRVR 9
            V+ SLSR+R
Sbjct: 3306 VKVSLSRIR 3314
>XP_005263349
          Length = 4410

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VQCSLSRVR 9
            V+ SLSR+R
Sbjct: 3613 VKVSLSRIR 3621
>XP_005263348
          Length = 4443

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VQCSLSRVR 9
            V+ SLSR+R
Sbjct: 3646 VKVSLSRIR 3654
>XP_005263347
          Length = 4640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VQCSLSRVR 9
            V+ SLSR+R
Sbjct: 4229 VKVSLSRIR 4237
>XP_005263346
          Length = 4983

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VQCSLSRVR 9
            V+ SLSR+R
Sbjct: 4186 VKVSLSRIR 4194
>XP_005263345
          Length = 4991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VQCSLSRVR 9
            V+ SLSR+R
Sbjct: 4194 VKVSLSRIR 4202
>XP_005263344
          Length = 5005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VQCSLSRVR 9
            V+ SLSR+R
Sbjct: 4208 VKVSLSRIR 4216
>XP_005263343
          Length = 5009

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VQCSLSRVR 9
            V+ SLSR+R
Sbjct: 4212 VKVSLSRIR 4220
>XP_005263342
          Length = 5025

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VQCSLSRVR 9
            V+ SLSR+R
Sbjct: 4228 VKVSLSRIR 4236
>XP_005263341
          Length = 5026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VQCSLSRVR 9
            V+ SLSR+R
Sbjct: 4229 VKVSLSRIR 4237
>XP_005263340
          Length = 5026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VQCSLSRVR 9
            V+ SLSR+R
Sbjct: 4229 VKVSLSRIR 4237
>XP_005263339
          Length = 5026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VQCSLSRVR 9
            V+ SLSR+R
Sbjct: 4229 VKVSLSRIR 4237
>NP_005742
          Length = 3907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    VQCSLSRVR 9
            VQC   +VR
Sbjct: 2008 VQCQAEKVR 2016
>NP_671714
          Length = 3899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    VQCSLSRVR 9
            VQC   +VR
Sbjct: 2008 VQCQAEKVR 2016
>NP_689969
          Length = 1708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   VQCSLSRV 8
           + C LSR+
Sbjct: 216 IDCQLSRI 223
>NP_001272368
          Length = 1732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   VQCSLSRV 8
           + C LSR+
Sbjct: 216 IDCQLSRI 223
>NP_060318
          Length = 1096

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    QCSLSR 7
            QC+LSR
Sbjct: 1055 QCALSR 1060
>NP_064716
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  VQCSLSRV 8
          + C LSRV
Sbjct: 9  IACQLSRV 16
>NP_660352
          Length = 192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VQCSLSRV 8
           V C+LSR+
Sbjct: 149 VLCTLSRI 156
>NP_001192067
          Length = 174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VQCSLSRV 8
           V C+LSR+
Sbjct: 131 VLCTLSRI 138
>NP_599025
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VQCSLSR 7
           V CS+SR
Sbjct: 398 VSCSMSR 404
>NP_006513
          Length = 365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   VQCSLSRVR 9
           VQC   RVR
Sbjct: 350 VQCHRCRVR 358
>NP_001035544
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VQCSLSR 7
           V CS+SR
Sbjct: 377 VSCSMSR 383
>NP_001268662
          Length = 651

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VQCSLSR 7
           V CS+SR
Sbjct: 291 VSCSMSR 297
>NP_075062
          Length = 759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VQCSLSR 7
           V CS+SR
Sbjct: 398 VSCSMSR 404
>NP_001268661
          Length = 723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VQCSLSR 7
           V CS+SR
Sbjct: 362 VSCSMSR 368
>XP_006718537
          Length = 192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VQCSLSRV 8
           V C+LSR+
Sbjct: 149 VLCTLSRI 156
>XP_006718536
          Length = 192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VQCSLSRV 8
           V C+LSR+
Sbjct: 149 VLCTLSRI 156
>XP_006718535
          Length = 192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VQCSLSRV 8
           V C+LSR+
Sbjct: 149 VLCTLSRI 156
>XP_006715890
          Length = 3860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    VQCSLSRVR 9
            VQC   +VR
Sbjct: 1961 VQCQAEKVR 1969
>XP_005250160
          Length = 3939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    VQCSLSRVR 9
            VQC   +VR
Sbjct: 2040 VQCQAEKVR 2048
>XP_005250159
          Length = 3952

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    VQCSLSRVR 9
            VQC   +VR
Sbjct: 2053 VQCQAEKVR 2061
>XP_006714526
          Length = 1670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   VQCSLSRV 8
           + C LSR+
Sbjct: 216 IDCQLSRI 223
>NP_602298
          Length = 740

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VQCSLSR 7
           V CS+SR
Sbjct: 398 VSCSMSR 404
>NP_036283
          Length = 371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VQCSLSRV 8
           V+C +SRV
Sbjct: 267 VRCEVSRV 274
>NP_001007525
          Length = 371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VQCSLSRV 8
           V+C +SRV
Sbjct: 267 VRCEVSRV 274
>NP_001007524
          Length = 371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VQCSLSRV 8
           V+C +SRV
Sbjct: 267 VRCEVSRV 274
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.335    0.131    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 635,378
Number of extensions: 645
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package