Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              19     665
NP_001025035                                                           17    3301
NP_663696                                                              17    3301
NP_056164                                                              16    7355
NP_653252                                                              16    7355
NP_071733                                                              16    7355
NP_778228                                                              16    7355
XP_006720785                                                           16    7355
XP_005274110                                                           16    7355
XP_005252859                                                           16    7355
XP_006718216                                                           16    7355
XP_006718215                                                           16    7355
XP_006718214                                                           16    7355
XP_006718213                                                           16    7355
XP_006718212                                                           16    7355
XP_005251225                                                           16    7355
XP_006716483                                                           16    7355
XP_005251224                                                           16    7355
XP_005249030                                                           16    7355
XP_005249029                                                           16    7355
NP_115821                                                              16    7355
NP_703148                                                              16    7355
NP_001161870                                                           15    9605
NP_006407                                                              15    9605
NP_078966                                                              15    9605
NP_689777                                                              15    9605
NP_060360                                                              15    9605
NP_001252506                                                           15    9605
NP_073567                                                              15    9605
NP_056058                                                              15    9605
NP_001269879                                                           15    9605
NP_001269878                                                           15    9605
NP_001251503                                                           15    9605
NP_001242935                                                           15    9605
NP_001139734                                                           15    9605
NP_001139733                                                           15    9605
NP_694994                                                              15    9605
NP_001139736                                                           15    9605
XP_005276776                                                           15    9605
XP_005262564                                                           15    9605
XP_006723004                                                           15    9605
XP_005257134                                                           15    9605
XP_006716574                                                           15    9605
XP_006716573                                                           15    9605
XP_005250858                                                           15    9605
XP_005250857                                                           15    9605
XP_006715622                                                           15    9605
XP_005267190                                                           15    9605
XP_005267189                                                           15    9605
XP_005267187                                                           15    9605
XP_005267185                                                           15    9605
XP_005267184                                                           15    9605
XP_006712756                                                           15    9605
XP_006712755                                                           15    9605
XP_006711326                                                           15    9605
XP_005273145                                                           15    9605
XP_006711325                                                           15    9605
XP_006710324                                                           15    9605
NP_009055                                                              15    9605
>NP_115803
          Length = 1156

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VPSLSTAVQ 9
           +PSLSTAVQ
Sbjct: 857 MPSLSTAVQ 865
>NP_001025035
          Length = 1200

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PSLSTAVQ 9
          PSL TA+Q
Sbjct: 4  PSLDTAIQ 11
>NP_663696
          Length = 615

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   VPSLSTA 7
           VPSLSTA
Sbjct: 558 VPSLSTA 564
>NP_056164
          Length = 1079

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PSLSTAVQ 9
           PSL +AVQ
Sbjct: 551 PSLGSAVQ 558
>NP_653252
          Length = 1463

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VPSLSTA 7
           VP+LSTA
Sbjct: 818 VPALSTA 824
>NP_071733
          Length = 449

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PSLSTAV 8
           PSLSTA+
Sbjct: 186 PSLSTAL 192
>NP_778228
          Length = 1121

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VPSLSTA 7
           VPSLST+
Sbjct: 852 VPSLSTS 858
>XP_006720785
          Length = 1079

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VPSLSTA 7
            VPSLST+
Sbjct: 1013 VPSLSTS 1019
>XP_005274110
          Length = 449

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PSLSTAV 8
           PSLSTA+
Sbjct: 186 PSLSTAL 192
>XP_005252859
          Length = 1272

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VPSLSTA 7
           VPSLST+
Sbjct: 852 VPSLSTS 858
>XP_006718216
          Length = 1298

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VPSLSTA 7
           VPSLST+
Sbjct: 852 VPSLSTS 858
>XP_006718215
          Length = 1325

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VPSLSTA 7
           VPSLST+
Sbjct: 879 VPSLSTS 885
>XP_006718214
          Length = 1338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VPSLSTA 7
           VPSLST+
Sbjct: 892 VPSLSTS 898
>XP_006718213
          Length = 1339

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VPSLSTA 7
           VPSLST+
Sbjct: 919 VPSLSTS 925
>XP_006718212
          Length = 1365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VPSLSTA 7
           VPSLST+
Sbjct: 919 VPSLSTS 925
>XP_005251225
          Length = 848

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VPSLSTA 7
           VP+LSTA
Sbjct: 203 VPALSTA 209
>XP_006716483
          Length = 1367

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VPSLSTA 7
           VP+LSTA
Sbjct: 722 VPALSTA 728
>XP_005251224
          Length = 1439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VPSLSTA 7
           VP+LSTA
Sbjct: 794 VPALSTA 800
>XP_005249030
          Length = 1079

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PSLSTAVQ 9
           PSL +AVQ
Sbjct: 551 PSLGSAVQ 558
>XP_005249029
          Length = 1079

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PSLSTAVQ 9
           PSL +AVQ
Sbjct: 551 PSLGSAVQ 558
>NP_115821
          Length = 1044

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VPSLSTA 7
           VPSLST+
Sbjct: 978 VPSLSTS 984
>NP_703148
          Length = 1200

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VPSLSTAVQ 9
           VP +S AVQ
Sbjct: 168 VPGISQAVQ 176
>NP_001161870
          Length = 278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VPSLSTAVQ 9
           VPSL  AVQ
Sbjct: 93  VPSLVYAVQ 101
>NP_006407
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VPSLSTAVQ 9
           VPSL  AVQ
Sbjct: 93  VPSLVYAVQ 101
>NP_078966
          Length = 14507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1     VPSLST 6
             VPSLST
Sbjct: 10416 VPSLST 10421
>NP_689777
          Length = 3997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VPSLSTAV 8
           +PS STA+
Sbjct: 760 IPSFSTAL 767
>NP_060360
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VPSLSTAV 8
           +PS STA+
Sbjct: 760 IPSFSTAL 767
>NP_001252506
          Length = 852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VPSLSTAVQ 9
           VP L+ AVQ
Sbjct: 238 VPGLTQAVQ 246
>NP_073567
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  VPSLSTAVQ 9
          +P LSTA Q
Sbjct: 85 LPELSTAQQ 93
>NP_056058
          Length = 863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VPSLSTAV 8
           +PS STA+
Sbjct: 760 IPSFSTAL 767
>NP_001269879
          Length = 273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  VPSLSTAVQ 9
          +P LSTA Q
Sbjct: 85 LPELSTAQQ 93
>NP_001269878
          Length = 230

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  VPSLSTAVQ 9
          +P LSTA Q
Sbjct: 51 LPELSTAQQ 59
>NP_001251503
          Length = 833

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VPSLSTAVQ 9
           VP L+ AVQ
Sbjct: 238 VPGLTQAVQ 246
>NP_001242935
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VPSLSTAV 8
           VPS STAV
Sbjct: 189 VPSDSTAV 196
>NP_001139734
          Length = 574

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VPSLSTAV 8
           VPS STAV
Sbjct: 227 VPSDSTAV 234
>NP_001139733
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VPSLSTAV 8
           VPS STAV
Sbjct: 272 VPSDSTAV 279
>NP_694994
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VPSLSTAV 8
           VPS STAV
Sbjct: 227 VPSDSTAV 234
>NP_001139736
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VPSLSTAV 8
           VPS STAV
Sbjct: 272 VPSDSTAV 279
>XP_005276776
          Length = 991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VPSLSTAVQ 9
           +PS+ST  Q
Sbjct: 667 IPSMSTIYQ 675
>XP_005262564
          Length = 991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VPSLSTAVQ 9
           +PS+ST  Q
Sbjct: 667 IPSMSTIYQ 675
>XP_006723004
          Length = 6443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    VPSLST 6
            VPSLST
Sbjct: 2330 VPSLST 2335
>XP_005257134
          Length = 842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VPSLSTAVQ 9
           VP L+ AVQ
Sbjct: 247 VPGLTQAVQ 255
>XP_006716574
          Length = 968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VPSLSTAV 8
           +PS STA+
Sbjct: 760 IPSFSTAL 767
>XP_006716573
          Length = 1776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VPSLSTAV 8
           +PS STA+
Sbjct: 760 IPSFSTAL 767
>XP_005250858
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VPSLSTAV 8
           +PS STA+
Sbjct: 760 IPSFSTAL 767
>XP_005250857
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VPSLSTAV 8
           +PS STA+
Sbjct: 760 IPSFSTAL 767
>XP_006715622
          Length = 2499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VPSLSTAV 8
           VP L+TA+
Sbjct: 958 VPELNTAI 965
>XP_005267190
          Length = 3424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VPSLSTAV 8
            VP L+TA+
Sbjct: 1883 VPELNTAI 1890
>XP_005267189
          Length = 3425

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VPSLSTAV 8
            VP L+TA+
Sbjct: 1897 VPELNTAI 1904
>XP_005267187
          Length = 3433

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VPSLSTAV 8
            VP L+TA+
Sbjct: 1892 VPELNTAI 1899
>XP_005267185
          Length = 3437

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VPSLSTAV 8
            VP L+TA+
Sbjct: 1896 VPELNTAI 1903
>XP_005267184
          Length = 3438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VPSLSTAV 8
            VP L+TA+
Sbjct: 1897 VPELNTAI 1904
>XP_006712756
          Length = 278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  VPSLSTAVQ 9
          +P LSTA Q
Sbjct: 85 LPELSTAQQ 93
>XP_006712755
          Length = 278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  VPSLSTAVQ 9
          +P LSTA Q
Sbjct: 85 LPELSTAQQ 93
>XP_006711326
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VPSLSTAV 8
           VPS STAV
Sbjct: 517 VPSDSTAV 524
>XP_005273145
          Length = 845

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VPSLSTAV 8
           VPS STAV
Sbjct: 517 VPSDSTAV 524
>XP_006711325
          Length = 864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VPSLSTAV 8
           VPS STAV
Sbjct: 517 VPSDSTAV 524
>XP_006710324
          Length = 943

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VPSLSTAVQ 9
           +PS+ST  Q
Sbjct: 619 IPSMSTIYQ 627
>NP_009055
          Length = 3433

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VPSLSTAV 8
            VP L+TA+
Sbjct: 1892 VPELNTAI 1899
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.112    0.275 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 489,987
Number of extensions: 661
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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