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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     509
XP_005262424                                                           20     509
NP_004677                                                              17    2528
NP_001161693                                                           17    3301
NP_660155                                                              17    3301
XP_005246404                                                           17    3301
XP_005270495                                                           17    3301
XP_006710403                                                           17    3301
NP_001003698                                                           17    4312
NP_001161816                                                           17    4312
NP_001003699                                                           17    4312
NP_001003700                                                           17    4312
XP_006715224                                                           17    4312
XP_005249329                                                           17    4312
XP_006715223                                                           17    4312
XP_006715222                                                           17    4312
XP_005249333                                                           17    4312
XP_006715221                                                           17    4312
XP_006715220                                                           17    4312
XP_005249332                                                           17    4312
XP_006715219                                                           17    4312
NP_115267                                                              17    4312
NP_061746                                                              17    4312
NP_078966                                                              16    5631
NP_001273762                                                           16    5631
NP_001107563                                                           16    5631
NP_001247                                                              16    5631
NP_055061                                                              16    5631
NP_005246                                                              16    5631
XP_006724446                                                           16    5631
XP_006723004                                                           16    5631
XP_006722284                                                           16    5631
XP_006722283                                                           16    5631
XP_006722282                                                           16    5631
XP_005257952                                                           16    5631
XP_006722281                                                           16    5631
XP_006722280                                                           16    5631
XP_005257949                                                           16    5631
XP_005272329                                                           16    5631
XP_006713937                                                           16    5631
XP_005272326                                                           16    5631
XP_005272325                                                           16    5631
NP_000740                                                              15    9605
NP_001276987                                                           15    9605
NP_001154945                                                           15    9605
NP_000685                                                              15    9605
NP_001034230                                                           15    9605
NP_061916                                                              15    9605
XP_006717514                                                           15    9605
XP_005272330                                                           15    9605
XP_005272327                                                           15    9605

>NP_722576
          Length = 3080

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   VPKSATTQ 8
           VPKSATTQ
Sbjct: 826 VPKSATTQ 833



>XP_005262424
          Length = 2875

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   VPKSATTQ 8
           VPKSATTQ
Sbjct: 621 VPKSATTQ 628



>NP_004677
          Length = 660

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VPKSATTQI 9
           VPKSAT  I
Sbjct: 167 VPKSATAHI 175



>NP_001161693
          Length = 1820

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   PKSATTQI 9
           P+SAT+QI
Sbjct: 922 PRSATSQI 929



>NP_660155
          Length = 891

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PKSATTQ 8
           PK+ATTQ
Sbjct: 250 PKNATTQ 256



>XP_005246404
          Length = 1821

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   PKSATTQI 9
           P+SAT+QI
Sbjct: 923 PRSATSQI 930



>XP_005270495
          Length = 517

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PKSATTQ 8
           PK+ATTQ
Sbjct: 250 PKNATTQ 256



>XP_006710403
          Length = 878

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   PKSATTQ 8
           PK+ATTQ
Sbjct: 237 PKNATTQ 243



>NP_001003698
          Length = 1687

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VPKSATT 7
            VPK+ATT
Sbjct: 1108 VPKAATT 1114



>NP_001161816
          Length = 1687

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VPKSATT 7
            VPK+ATT
Sbjct: 1108 VPKAATT 1114



>NP_001003699
          Length = 1742

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VPKSATT 7
            VPK+ATT
Sbjct: 1108 VPKAATT 1114



>NP_001003700
          Length = 1476

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VPKSATT 7
            VPK+ATT
Sbjct: 1108 VPKAATT 1114



>XP_006715224
          Length = 1742

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VPKSATT 7
            VPK+ATT
Sbjct: 1108 VPKAATT 1114



>XP_005249329
          Length = 1742

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VPKSATT 7
            VPK+ATT
Sbjct: 1108 VPKAATT 1114



>XP_006715223
          Length = 1742

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VPKSATT 7
            VPK+ATT
Sbjct: 1108 VPKAATT 1114



>XP_006715222
          Length = 1742

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VPKSATT 7
            VPK+ATT
Sbjct: 1108 VPKAATT 1114



>XP_005249333
          Length = 1742

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VPKSATT 7
            VPK+ATT
Sbjct: 1108 VPKAATT 1114



>XP_006715221
          Length = 1742

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VPKSATT 7
            VPK+ATT
Sbjct: 1108 VPKAATT 1114



>XP_006715220
          Length = 1742

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VPKSATT 7
            VPK+ATT
Sbjct: 1108 VPKAATT 1114



>XP_005249332
          Length = 1742

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VPKSATT 7
            VPK+ATT
Sbjct: 1108 VPKAATT 1114



>XP_006715219
          Length = 1742

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VPKSATT 7
            VPK+ATT
Sbjct: 1108 VPKAATT 1114



>NP_115267
          Length = 811

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PKSATTQI 9
           P+S TTQI
Sbjct: 221 PQSGTTQI 228



>NP_061746
          Length = 931

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PKSATTQI 9
           P+S TTQI
Sbjct: 221 PQSGTTQI 228



>NP_078966
          Length = 14507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VPKSATTQI 9
            VP  ATT++
Sbjct: 8440 VPSGATTEV 8448



>NP_001273762
          Length = 1213

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VPKSATT 7
            +PK+ATT
Sbjct: 1008 IPKTATT 1014




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VPKSATT 7
           VP++ATT
Sbjct: 576 VPRNATT 582



>NP_001107563
          Length = 830

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VPKSATTQI 9
           +P S TTQ+
Sbjct: 180 LPNSCTTQV 188



>NP_001247
          Length = 824

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VPKSATTQI 9
           +P S TTQ+
Sbjct: 180 LPNSCTTQV 188



>NP_055061
          Length = 3014

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PKSATTQI 9
           P+SATT I
Sbjct: 332 PRSATTYI 339



>NP_005246
          Length = 1311

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VPKSATT 7
            +PK+ATT
Sbjct: 1106 IPKTATT 1112




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VPKSATT 7
           VP++ATT
Sbjct: 674 VPRNATT 680



>XP_006724446
          Length = 3019

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PKSATTQI 9
           P+SATT I
Sbjct: 332 PRSATTYI 339



>XP_006723004
          Length = 6443

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VPKSATTQI 9
           VP  ATT++
Sbjct: 354 VPSGATTEV 362



>XP_006722284
          Length = 689

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VPKSATTQI 9
          +P S TTQ+
Sbjct: 45 LPNSCTTQV 53



>XP_006722283
          Length = 742

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VPKSATTQI 9
           +P S TTQ+
Sbjct: 98  LPNSCTTQV 106



>XP_006722282
          Length = 763

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VPKSATTQI 9
           +P S TTQ+
Sbjct: 119 LPNSCTTQV 127



>XP_005257952
          Length = 763

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VPKSATTQI 9
           +P S TTQ+
Sbjct: 119 LPNSCTTQV 127



>XP_006722281
          Length = 769

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VPKSATTQI 9
           +P S TTQ+
Sbjct: 180 LPNSCTTQV 188



>XP_006722280
          Length = 799

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VPKSATTQI 9
           +P S TTQ+
Sbjct: 180 LPNSCTTQV 188



>XP_005257949
          Length = 823

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VPKSATTQI 9
           +P S TTQ+
Sbjct: 180 LPNSCTTQV 188



>XP_005272329
          Length = 1175

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VPKSATT 7
           +PK+ATT
Sbjct: 970 IPKTATT 976




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VPKSATT 7
           VP++ATT
Sbjct: 538 VPRNATT 544



>XP_006713937
          Length = 1249

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VPKSATT 7
            +PK+ATT
Sbjct: 1044 IPKTATT 1050




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VPKSATT 7
           VP++ATT
Sbjct: 612 VPRNATT 618



>XP_005272326
          Length = 1262

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VPKSATT 7
            +PK+ATT
Sbjct: 1057 IPKTATT 1063




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VPKSATT 7
           VP++ATT
Sbjct: 674 VPRNATT 680



>XP_005272325
          Length = 1300

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VPKSATT 7
            +PK+ATT
Sbjct: 1095 IPKTATT 1101




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VPKSATT 7
           VP++ATT
Sbjct: 674 VPRNATT 680



>NP_000740
          Length = 458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  VPKSATT 7
          +P SATT
Sbjct: 14 IPSSATT 20



>NP_001276987
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VPKSATTQI 9
          VPK+  TQ+
Sbjct: 87 VPKNLATQL 95



>NP_001154945
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VPKSATTQI 9
          VPK+  TQ+
Sbjct: 87 VPKNLATQL 95



>NP_000685
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VPKSATTQI 9
          VPK+  TQ+
Sbjct: 87 VPKNLATQL 95



>NP_001034230
          Length = 2365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   VPKSATTQ 8
           +P+S++TQ
Sbjct: 823 IPRSSSTQ 830



>NP_061916
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   PKSATTQ 8
           PK+ TTQ
Sbjct: 458 PKTGTTQ 464



>XP_006717514
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   PKSATTQ 8
           PK+ TTQ
Sbjct: 458 PKTGTTQ 464



>XP_005272330
          Length = 1140

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VPKSATT 7
           VP++ATT
Sbjct: 674 VPRNATT 680



>XP_005272327
          Length = 1236

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VPKSATT 7
           VP++ATT
Sbjct: 674 VPRNATT 680



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.303    0.112    0.283 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 433,830
Number of extensions: 616
Number of successful extensions: 57
Number of sequences better than 10000.0: 51
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)