Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              20     390
NP_009297                                                              20     390
NP_689777                                                              18    1135
NP_060360                                                              18    1135
XP_005250858                                                           18    1135
XP_005250857                                                           18    1135
NP_056142                                                              18    1935
XP_006711311                                                           18    1935
XP_005245106                                                           18    1935
NP_976328                                                              17    3301
NP_065169                                                              16    5631
NP_056975                                                              16    5631
NP_001070671                                                           16    5631
NP_001269732                                                           16    5631
NP_001269731                                                           16    5631
NP_001269730                                                           16    5631
NP_065705                                                              16    5631
XP_006723898                                                           16    5631
XP_006723897                                                           16    5631
XP_005260524                                                           16    5631
XP_006719020                                                           16    5631
XP_006719019                                                           16    5631
XP_005247719                                                           16    5631
NP_997046                                                              16    5631
NP_065391                                                              16    7355
NP_001127812                                                           16    7355
NP_115678                                                              16    7355
XP_005261680                                                           16    7355
XP_006715855                                                           16    7355
NP_001124491                                                           15    9605
NP_001229305                                                           15    9605
NP_002046                                                              15    9605
NP_002010                                                              15    9605
NP_055999                                                              15    9605
NP_001137854                                                           15    9605
NP_001103132                                                           15    9605
NP_653267                                                              15    9605
NP_660281                                                              15    9605
NP_579812                                                              15    9605
NP_579803                                                              15    9605
NP_065868                                                              15    9605
NP_065811                                                              15    9605
XP_005247738                                                           15    9605
XP_005247737                                                           15    9605
XP_006713778                                                           15    9605
XP_006713136                                                           15    9605
XP_006712712                                                           15    9605
XP_006712711                                                           15    9605
XP_006712710                                                           15    9605
XP_006712709                                                           15    9605
XP_006710939                                                           15    9605
XP_005271228                                                           15    9605
XP_006710938                                                           15    9605
XP_006710937                                                           15    9605
NP_579807                                                              15    9605
NP_001991                                                              15    9605
NP_579806                                                              15    9605
NP_579805                                                              15    9605
NP_579811                                                              15    9605
>NP_005148
          Length = 1130

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VNSDVAKPS 9
           VNSD AKPS
Sbjct: 941 VNSDAAKPS 949
>NP_009297
          Length = 1149

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VNSDVAKPS 9
           VNSD AKPS
Sbjct: 960 VNSDAAKPS 968
>NP_689777
          Length = 3997

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1    VNSDVAKPS 9
            V+SDVAKP+
Sbjct: 1855 VDSDVAKPN 1863
>NP_060360
          Length = 4022

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1    VNSDVAKPS 9
            V+SDVAKP+
Sbjct: 1880 VDSDVAKPN 1888
>XP_005250858
          Length = 4022

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1    VNSDVAKPS 9
            V+SDVAKP+
Sbjct: 1880 VDSDVAKPN 1888
>XP_005250857
          Length = 4022

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1    VNSDVAKPS 9
            V+SDVAKP+
Sbjct: 1880 VDSDVAKPN 1888
>NP_056142
          Length = 1016

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VNSDVAKPS 9
           VN DV KPS
Sbjct: 608 VNGDVDKPS 616
>XP_006711311
          Length = 950

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VNSDVAKPS 9
           VN DV KPS
Sbjct: 542 VNGDVDKPS 550
>XP_005245106
          Length = 970

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VNSDVAKPS 9
           VN DV KPS
Sbjct: 562 VNGDVDKPS 570
>NP_976328
          Length = 911

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSDVAKPS 9
           N+DV KPS
Sbjct: 685 NTDVEKPS 692
>NP_065169
          Length = 1053

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VNSDVAKPS 9
            +++DV KPS
Sbjct: 1023 ISADVEKPS 1031
>NP_056975
          Length = 579

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   DVAKPS 9
           DVAKPS
Sbjct: 204 DVAKPS 209
>NP_001070671
          Length = 985

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NSDVAKPS 9
           N+D AKP+
Sbjct: 640 NTDAAKPT 647
>NP_001269732
          Length = 886

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NSDVAKPS 9
           N+D AKP+
Sbjct: 541 NTDAAKPT 548
>NP_001269731
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NSDVAKPS 9
           N+D AKP+
Sbjct: 672 NTDAAKPT 679
>NP_001269730
          Length = 984

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NSDVAKPS 9
           N+D AKP+
Sbjct: 639 NTDAAKPT 646
>NP_065705
          Length = 1050

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NSDVAKPS 9
           N+D AKP+
Sbjct: 705 NTDAAKPT 712
>XP_006723898
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNSDVAKPS 9
           +++DV KPS
Sbjct: 921 ISADVEKPS 929
>XP_006723897
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNSDVAKPS 9
           +++DV KPS
Sbjct: 921 ISADVEKPS 929
>XP_005260524
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNSDVAKPS 9
           +++DV KPS
Sbjct: 921 ISADVEKPS 929
>XP_006719020
          Length = 150

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSDVAKPS 9
          +SD AKPS
Sbjct: 21 DSDFAKPS 28
>XP_006719019
          Length = 330

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSDVAKPS 9
          +SD AKPS
Sbjct: 21 DSDFAKPS 28
>XP_005247719
          Length = 919

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NSDVAKPS 9
           N+D AKP+
Sbjct: 574 NTDAAKPT 581
>NP_997046
          Length = 547

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VNSDVAKP 8
           VNSD +KP
Sbjct: 156 VNSDNSKP 163
>NP_065391
          Length = 252

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NSDVAKPS 9
           NSD A+P+
Sbjct: 159 NSDTAEPT 166
>NP_001127812
          Length = 122

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VNSDVAKP 8
          V SDV+KP
Sbjct: 53 VASDVSKP 60
>NP_115678
          Length = 122

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VNSDVAKP 8
          V SDV+KP
Sbjct: 53 VASDVSKP 60
>XP_005261680
          Length = 303

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NSDVAKPS 9
           NSD A+P+
Sbjct: 210 NSDTAEPT 217
>XP_006715855
          Length = 122

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VNSDVAKP 8
          V SDV+KP
Sbjct: 53 VASDVSKP 60
>NP_001124491
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   VNSDVAKP 8
           V  DVAKP
Sbjct: 222 VELDVAKP 229
>NP_001229305
          Length = 438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   VNSDVAKP 8
           V  DVAKP
Sbjct: 222 VELDVAKP 229
>NP_002046
          Length = 432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   VNSDVAKP 8
           V  DVAKP
Sbjct: 222 VELDVAKP 229
>NP_002010
          Length = 1338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SDVAKPS 9
            SDV++PS
Sbjct: 1285 SDVSRPS 1291
>NP_055999
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NSDVAKP 8
           N+DV KP
Sbjct: 978 NADVQKP 984
>NP_001137854
          Length = 1127

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    NSDVAKP 8
            N+DV KP
Sbjct: 1104 NADVQKP 1110
>NP_001103132
          Length = 4284

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VNSDVAKPS 9
            VNS + KPS
Sbjct: 1319 VNSLIQKPS 1327
>NP_653267
          Length = 4753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SDVAKPS 9
            SDVA+P+
Sbjct: 3974 SDVARPA 3980
>NP_660281
          Length = 1043

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   NSDVAKPS 9
           N D  KPS
Sbjct: 608 NEDAVKPS 615
>NP_579812
          Length = 253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NSDVAKPS 9
           ++DVA+PS
Sbjct: 226 SADVAEPS 233
>NP_579803
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NSDVAKPS 9
           ++DVA+PS
Sbjct: 238 SADVAEPS 245
>NP_065868
          Length = 936

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   VNSDVAKP 8
           VNS VA P
Sbjct: 622 VNSPVASP 629
>NP_065811
          Length = 1572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   VNSDVAKPS 9
           VN D+  PS
Sbjct: 344 VNGDLGSPS 352
>XP_005247738
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   VNSDVAKP 8
           VNS VA P
Sbjct: 301 VNSPVASP 308
>XP_005247737
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   VNSDVAKP 8
           VNS VA P
Sbjct: 600 VNSPVASP 607
>XP_006713778
          Length = 923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   VNSDVAKP 8
           VNS VA P
Sbjct: 609 VNSPVASP 616
>XP_006713136
          Length = 1022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    NSDVAKP 8
            N+DV KP
Sbjct: 999  NADVQKP 1005
>XP_006712712
          Length = 1414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   VNSDVAKPS 9
           VN D+  PS
Sbjct: 186 VNGDLGSPS 194
>XP_006712711
          Length = 1448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   VNSDVAKPS 9
           VN D+  PS
Sbjct: 220 VNGDLGSPS 228
>XP_006712710
          Length = 1528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   VNSDVAKPS 9
           VN D+  PS
Sbjct: 351 VNGDLGSPS 359
>XP_006712709
          Length = 1579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   VNSDVAKPS 9
           VN D+  PS
Sbjct: 351 VNGDLGSPS 359
>XP_006710939
          Length = 989

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   NSDVAKPS 9
           N D  KPS
Sbjct: 554 NEDAVKPS 561
>XP_005271228
          Length = 1042

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   NSDVAKPS 9
           N D  KPS
Sbjct: 607 NEDAVKPS 614
>XP_006710938
          Length = 1043

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   NSDVAKPS 9
           N D  KPS
Sbjct: 608 NEDAVKPS 615
>XP_006710937
          Length = 1043

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   NSDVAKPS 9
           N D  KPS
Sbjct: 608 NEDAVKPS 615
>NP_579807
          Length = 179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NSDVAKPS 9
           ++DVA+PS
Sbjct: 152 SADVAEPS 159
>NP_001991
          Length = 287

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NSDVAKPS 9
           ++DVA+PS
Sbjct: 260 SADVAEPS 267
>NP_579806
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NSDVAKPS 9
           ++DVA+PS
Sbjct: 248 SADVAEPS 255
>NP_579805
          Length = 191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NSDVAKPS 9
           ++DVA+PS
Sbjct: 164 SADVAEPS 171
>NP_579811
          Length = 178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NSDVAKPS 9
           ++DVA+PS
Sbjct: 151 SADVAEPS 158
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.294    0.112    0.286 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 664,585
Number of extensions: 1108
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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