Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              20     299
NP_444254                                                              20     299
NP_444253                                                              20     299
NP_444255                                                              20     299
XP_005247551                                                           20     299
XP_005247550                                                           20     299
XP_006713712                                                           20     299
XP_005247549                                                           20     299
NP_001026851                                                           17    3301
NP_004928                                                              17    3301
NP_001138617                                                           17    3301
NP_005619                                                              17    3301
XP_005259224                                                           17    3301
XP_006721526                                                           17    3301
XP_005256542                                                           17    3301
NP_005763                                                              17    4312
NP_001244073                                                           16    5631
NP_001244074                                                           16    5631
NP_689651                                                              16    5631
NP_085911                                                              16    5631
NP_004390                                                              16    5631
XP_006719116                                                           16    5631
XP_006719115                                                           16    5631
XP_005253390                                                           16    5631
XP_006719114                                                           16    5631
XP_006719113                                                           16    5631
XP_006719112                                                           16    5631
XP_006719111                                                           16    5631
XP_006719110                                                           16    5631
XP_006719109                                                           16    5631
XP_006719108                                                           16    5631
XP_006719107                                                           16    5631
XP_005253388                                                           16    5631
XP_006719106                                                           16    5631
XP_006719105                                                           16    5631
XP_006719104                                                           16    5631
XP_005253105                                                           16    5631
XP_005249358                                                           16    5631
XP_005249357                                                           16    5631
XP_005249356                                                           16    5631
NP_115487                                                              16    5631
NP_853553                                                              16    7355
NP_955751                                                              16    7355
XP_005264449                                                           16    7355
NP_001258754                                                           15    9605
NP_001258753                                                           15    9605
NP_004559                                                              15    9605
NP_976221                                                              15    9605
NP_001230829                                                           15    9605
NP_005327                                                              15    9605
NP_001182220                                                           15    9605
NP_001258752                                                           15    9605
NP_001258751                                                           15    9605
NP_001027018                                                           15    9605
NP_002631                                                              15    9605
NP_942130                                                              15    9605
XP_006722547                                                           15    9605
XP_006715176                                                           15    9605
XP_006715175                                                           15    9605
XP_005249238                                                           15    9605
XP_006712539                                                           15    9605
XP_005247059                                                           15    9605
XP_005247058                                                           15    9605
XP_006712538                                                           15    9605
XP_005247060                                                           15    9605
XP_005247057                                                           15    9605
>NP_444256
          Length = 1794

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VNQTGTRIK 9
            VN+TGTRIK
Sbjct: 1525 VNKTGTRIK 1533
>NP_444254
          Length = 1845

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VNQTGTRIK 9
            VN+TGTRIK
Sbjct: 1525 VNKTGTRIK 1533
>NP_444253
          Length = 1914

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VNQTGTRIK 9
            VN+TGTRIK
Sbjct: 1594 VNKTGTRIK 1602
>NP_444255
          Length = 1863

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VNQTGTRIK 9
            VN+TGTRIK
Sbjct: 1594 VNKTGTRIK 1602
>XP_005247551
          Length = 1855

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VNQTGTRIK 9
            VN+TGTRIK
Sbjct: 1535 VNKTGTRIK 1543
>XP_005247550
          Length = 1856

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VNQTGTRIK 9
            VN+TGTRIK
Sbjct: 1536 VNKTGTRIK 1544
>XP_006713712
          Length = 1923

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VNQTGTRIK 9
            VN+TGTRIK
Sbjct: 1604 VNKTGTRIK 1612
>XP_005247549
          Length = 1924

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VNQTGTRIK 9
            VN+TGTRIK
Sbjct: 1604 VNKTGTRIK 1612
>NP_001026851
          Length = 400

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NQTGTRIK 9
           NQTG RI+
Sbjct: 107 NQTGPRIR 114
>NP_004928
          Length = 367

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NQTGTRIK 9
           NQTG RI+
Sbjct: 107 NQTGPRIR 114
>NP_001138617
          Length = 339

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NQTGTRIK 9
          N TGTR+K
Sbjct: 10 NITGTRVK 17
>NP_005619
          Length = 541

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NQTGTRIK 9
           N TGTR+K
Sbjct: 212 NITGTRVK 219
>XP_005259224
          Length = 469

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NQTGTRIK 9
           N TGTR+K
Sbjct: 212 NITGTRVK 219
>XP_006721526
          Length = 400

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NQTGTRIK 9
           NQTG RI+
Sbjct: 107 NQTGPRIR 114
>XP_005256542
          Length = 400

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NQTGTRIK 9
           NQTG RI+
Sbjct: 107 NQTGPRIR 114
>NP_005763
          Length = 373

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  VNQTGTRI 8
          +NQTGT +
Sbjct: 66 INQTGTTL 73
>NP_001244073
          Length = 970

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 468 LSQTGTELK 476
>NP_001244074
          Length = 880

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 442 LSQTGTELK 450
>NP_689651
          Length = 970

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 468 LSQTGTELK 476
>NP_085911
          Length = 906

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 468 LSQTGTELK 476
>NP_004390
          Length = 856

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 468 LSQTGTELK 476
>XP_006719116
          Length = 787

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 260 LSQTGTELK 268
>XP_006719115
          Length = 845

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 504 LSQTGTELK 512
>XP_005253390
          Length = 942

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 504 LSQTGTELK 512
>XP_006719114
          Length = 954

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 504 LSQTGTELK 512
>XP_006719113
          Length = 967

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 504 LSQTGTELK 512
>XP_006719112
          Length = 969

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 442 LSQTGTELK 450
>XP_006719111
          Length = 969

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 442 LSQTGTELK 450
>XP_006719110
          Length = 995

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 468 LSQTGTELK 476
>XP_006719109
          Length = 995

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 468 LSQTGTELK 476
>XP_006719108
          Length = 995

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 468 LSQTGTELK 476
>XP_006719107
          Length = 995

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 468 LSQTGTELK 476
>XP_005253388
          Length = 1006

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 504 LSQTGTELK 512
>XP_006719106
          Length = 1018

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 504 LSQTGTELK 512
>XP_006719105
          Length = 1031

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 504 LSQTGTELK 512
>XP_006719104
          Length = 1031

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VNQTGTRIK 9
           ++QTGT +K
Sbjct: 504 LSQTGTELK 512
>XP_005253105
          Length = 424

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  QTGTRIK 9
          +TGTR+K
Sbjct: 10 RTGTRVK 16
>XP_005249358
          Length = 145

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NQTGTRIK 9
           N  GTRIK
Sbjct: 113 NPVGTRIK 120
>XP_005249357
          Length = 145

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NQTGTRIK 9
           N  GTRIK
Sbjct: 113 NPVGTRIK 120
>XP_005249356
          Length = 198

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NQTGTRIK 9
           N  GTRIK
Sbjct: 166 NPVGTRIK 173
>NP_115487
          Length = 145

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NQTGTRIK 9
           N  GTRIK
Sbjct: 113 NPVGTRIK 120
>NP_853553
          Length = 410

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VNQTGTRI 8
           + QTGTR+
Sbjct: 252 LGQTGTRL 259
>NP_955751
          Length = 229

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NQTGTRI 8
           NQTG R+
Sbjct: 188 NQTGVRL 194
>XP_005264449
          Length = 467

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VNQTGTRI 8
           + QTGTR+
Sbjct: 309 LGQTGTRL 316
>NP_001258754
          Length = 376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VNQTGTR 7
          VN+TGT+
Sbjct: 79 VNKTGTQ 85
>NP_001258753
          Length = 376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VNQTGTR 7
          VN+TGT+
Sbjct: 79 VNKTGTQ 85
>NP_004559
          Length = 376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VNQTGTR 7
          VN+TGT+
Sbjct: 79 VNKTGTQ 85
>NP_976221
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VNQTGTRI 8
           + +TGTRI
Sbjct: 249 MQETGTRI 256
>NP_001230829
          Length = 1235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VNQTGTRI 8
           + +TGTRI
Sbjct: 285 MQETGTRI 292
>NP_005327
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VNQTGTRI 8
           + +TGTRI
Sbjct: 249 MQETGTRI 256
>NP_001182220
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VNQTGTR 7
          VN+TGT+
Sbjct: 83 VNKTGTQ 89
>NP_001258752
          Length = 395

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VNQTGTR 7
           VN+TGT+
Sbjct: 98  VNKTGTQ 104
>NP_001258751
          Length = 390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VNQTGTR 7
          VN+TGT+
Sbjct: 93 VNKTGTQ 99
>NP_001027018
          Length = 242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VNQTGTR 7
          VN+TGT+
Sbjct: 77 VNRTGTQ 83
>NP_002631
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VNQTGTR 7
          VN+TGT+
Sbjct: 77 VNRTGTQ 83
>NP_942130
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VNQTGTR 7
          VN+TGT+
Sbjct: 77 VNRTGTQ 83
>XP_006722547
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VNQTGTR 7
          VN+TGT+
Sbjct: 77 VNRTGTQ 83
>XP_006715176
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VNQTGTR 7
          VN+TGT+
Sbjct: 83 VNKTGTQ 89
>XP_006715175
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VNQTGTR 7
          VN+TGT+
Sbjct: 83 VNKTGTQ 89
>XP_005249238
          Length = 409

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VNQTGTR 7
           VN+TGT+
Sbjct: 112 VNKTGTQ 118
>XP_006712539
          Length = 1250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VNQTGTRI 8
           + +TGTRI
Sbjct: 249 MQETGTRI 256
>XP_005247059
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VNQTGTRI 8
           + +TGTRI
Sbjct: 249 MQETGTRI 256
>XP_005247058
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VNQTGTRI 8
           + +TGTRI
Sbjct: 249 MQETGTRI 256
>XP_006712538
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VNQTGTRI 8
           + +TGTRI
Sbjct: 249 MQETGTRI 256
>XP_005247060
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VNQTGTRI 8
           + +TGTRI
Sbjct: 249 MQETGTRI 256
>XP_005247057
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VNQTGTRI 8
           + +TGTRI
Sbjct: 249 MQETGTRI 256
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.126    0.333 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 490,228
Number of extensions: 662
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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