Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001895                                                              19     665
NP_001091680                                                           19     665
NP_001091679                                                           19     665
XP_006713048                                                           19     665
XP_006713047                                                           19     665
XP_006713046                                                           19     665
XP_005264943                                                           19     665
NP_002221                                                              18    1935
NP_068831                                                              18    1935
XP_006721941                                                           18    1935
XP_006721940                                                           18    1935
XP_006721939                                                           18    1935
XP_006721938                                                           18    1935
XP_006721937                                                           18    1935
XP_006721936                                                           18    1935
XP_006721935                                                           18    1935
XP_006721934                                                           18    1935
XP_005257370                                                           18    1935
NP_996774                                                              17    3301
NP_996773                                                              17    3301
NP_996772                                                              17    3301
NP_001139587                                                           17    3301
NP_001139588                                                           17    3301
NP_055966                                                              17    3301
XP_006724043                                                           17    3301
NP_001139586                                                           17    3301
NP_001128530                                                           17    4312
NP_004077                                                              17    4312
XP_006720136                                                           17    4312
NP_001091896                                                           16    7355
NP_689755                                                              16    7355
NP_001138550                                                           16    7355
NP_064527                                                              16    7355
NP_001018857                                                           16    7355
XP_005257661                                                           16    7355
XP_005269091                                                           16    7355
XP_005269090                                                           16    7355
XP_006714174                                                           16    7355
NP_004577                                                              15    9605
NP_733762                                                              15    9605
NP_004177                                                              15    9605
XP_005274634                                                           15    9605
XP_006724570                                                           15    9605
XP_005274633                                                           15    9605
XP_005274632                                                           15    9605
XP_006724569                                                           15    9605
XP_005274630                                                           15    9605
XP_006724568                                                           15    9605
XP_006716738                                                           15    9605
XP_006716737                                                           15    9605
XP_005272407                                                           15    9605
XP_006713860                                                           15    9605
XP_006713859                                                           15    9605
XP_005247910                                                           15    9605
XP_005247909                                                           15    9605
XP_006713353                                                           15    9605
XP_005265439                                                           15    9605
XP_005265438                                                           15    9605
NP_116291                                                              15    9605
>NP_001895
          Length = 781

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VNFLAITTD 9
           V FLAITTD
Sbjct: 291 VKFLAITTD 299
>NP_001091680
          Length = 781

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VNFLAITTD 9
           V FLAITTD
Sbjct: 291 VKFLAITTD 299
>NP_001091679
          Length = 781

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VNFLAITTD 9
           V FLAITTD
Sbjct: 291 VKFLAITTD 299
>XP_006713048
          Length = 720

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VNFLAITTD 9
           V FLAITTD
Sbjct: 291 VKFLAITTD 299
>XP_006713047
          Length = 774

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VNFLAITTD 9
           V FLAITTD
Sbjct: 284 VKFLAITTD 292
>XP_006713046
          Length = 774

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VNFLAITTD 9
           V FLAITTD
Sbjct: 284 VKFLAITTD 292
>XP_005264943
          Length = 781

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VNFLAITTD 9
           V FLAITTD
Sbjct: 291 VKFLAITTD 299
>NP_002221
          Length = 745

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLAITTD
Sbjct: 284 FLAITTD 290
>NP_068831
          Length = 745

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLAITTD
Sbjct: 284 FLAITTD 290
>XP_006721941
          Length = 745

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLAITTD
Sbjct: 284 FLAITTD 290
>XP_006721940
          Length = 745

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLAITTD
Sbjct: 284 FLAITTD 290
>XP_006721939
          Length = 745

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLAITTD
Sbjct: 284 FLAITTD 290
>XP_006721938
          Length = 745

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLAITTD
Sbjct: 284 FLAITTD 290
>XP_006721937
          Length = 745

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLAITTD
Sbjct: 284 FLAITTD 290
>XP_006721936
          Length = 745

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLAITTD
Sbjct: 284 FLAITTD 290
>XP_006721935
          Length = 762

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLAITTD
Sbjct: 301 FLAITTD 307
>XP_006721934
          Length = 783

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLAITTD
Sbjct: 322 FLAITTD 328
>XP_005257370
          Length = 783

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLAITTD
Sbjct: 322 FLAITTD 328
>NP_996774
          Length = 812

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLA+TTD
Sbjct: 452 FLALTTD 458
>NP_996773
          Length = 841

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLA+TTD
Sbjct: 452 FLALTTD 458
>NP_996772
          Length = 889

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLA+TTD
Sbjct: 452 FLALTTD 458
>NP_001139587
          Length = 798

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLA+TTD
Sbjct: 409 FLALTTD 415
>NP_001139588
          Length = 1567

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLA+TTD
Sbjct: 448 FLALTTD 454
>NP_055966
          Length = 1571

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLA+TTD
Sbjct: 452 FLALTTD 458
>XP_006724043
          Length = 1174

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLA+TTD
Sbjct: 452 FLALTTD 458
>NP_001139586
          Length = 1110

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLA+TTD
Sbjct: 388 FLALTTD 394
>NP_001128530
          Length = 550

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NFLAITTD 9
           NFL I TD
Sbjct: 468 NFLVIVTD 475
>NP_004077
          Length = 550

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NFLAITTD 9
           NFL I TD
Sbjct: 468 NFLVIVTD 475
>XP_006720136
          Length = 550

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NFLAITTD 9
           NFL I TD
Sbjct: 468 NFLVIVTD 475
>NP_001091896
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NFLAITTD 9
           NFLA TT+
Sbjct: 422 NFLASTTN 429
>NP_689755
          Length = 372

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NFLAITTD 9
           +FL +TTD
Sbjct: 291 SFLVLTTD 298
>NP_001138550
          Length = 494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NFLAITTD 9
           NFL +TT+
Sbjct: 460 NFLNVTTE 467
>NP_064527
          Length = 87

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  FLAITTD 9
          FLA++TD
Sbjct: 70 FLAVSTD 76
>NP_001018857
          Length = 627

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NFLAITTD 9
           NFL +TT+
Sbjct: 593 NFLNVTTE 600
>XP_005257661
          Length = 456

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NFLAITTD 9
           NFLA TT+
Sbjct: 347 NFLASTTN 354
>XP_005269091
          Length = 130

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLA++TD
Sbjct: 113 FLAVSTD 119
>XP_005269090
          Length = 161

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FLAITTD 9
           FLA++TD
Sbjct: 144 FLAVSTD 150
>XP_006714174
          Length = 372

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NFLAITTD 9
           +FL +TTD
Sbjct: 291 SFLVLTTD 298
>NP_004577
          Length = 740

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NFLAITTD 9
           +F+AIT+D
Sbjct: 386 SFVAITSD 393
>NP_733762
          Length = 982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NFLAIT 7
           NFLA+T
Sbjct: 251 NFLAVT 256
>NP_004177
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  NFLAITTD 9
          NFL  TTD
Sbjct: 49 NFLLNTTD 56
>XP_005274634
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NFLAITTD 9
           +F+AIT+D
Sbjct: 357 SFVAITSD 364
>XP_006724570
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NFLAITTD 9
           +F+AIT+D
Sbjct: 358 SFVAITSD 365
>XP_005274633
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NFLAITTD 9
           +F+AIT+D
Sbjct: 357 SFVAITSD 364
>XP_005274632
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NFLAITTD 9
           +F+AIT+D
Sbjct: 358 SFVAITSD 365
>XP_006724569
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NFLAITTD 9
           +F+AIT+D
Sbjct: 358 SFVAITSD 365
>XP_005274630
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NFLAITTD 9
           +F+AIT+D
Sbjct: 386 SFVAITSD 393
>XP_006724568
          Length = 740

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NFLAITTD 9
           +F+AIT+D
Sbjct: 386 SFVAITSD 393
>XP_006716738
          Length = 528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NFLAITTD 9
           N LA+ TD
Sbjct: 162 NLLAVNTD 169
>XP_006716737
          Length = 528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NFLAITTD 9
           N LA+ TD
Sbjct: 162 NLLAVNTD 169
>XP_005272407
          Length = 528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NFLAITTD 9
           N LA+ TD
Sbjct: 162 NLLAVNTD 169
>XP_006713860
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NFLAIT 7
           NFLA+T
Sbjct: 279 NFLAVT 284
>XP_006713859
          Length = 966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NFLAIT 7
           NFLA+T
Sbjct: 279 NFLAVT 284
>XP_005247910
          Length = 982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NFLAIT 7
           NFLA+T
Sbjct: 251 NFLAVT 256
>XP_005247909
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NFLAIT 7
           NFLA+T
Sbjct: 279 NFLAVT 284
>XP_006713353
          Length = 484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  NFLAITTD 9
          NFL  TTD
Sbjct: 49 NFLLNTTD 56
>XP_005265439
          Length = 754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  NFLAITTD 9
          NFL  TTD
Sbjct: 49 NFLLNTTD 56
>XP_005265438
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  NFLAITTD 9
          NFL  TTD
Sbjct: 49 NFLLNTTD 56
>NP_116291
          Length = 528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NFLAITTD 9
           N LA+ TD
Sbjct: 162 NLLAVNTD 169
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.138    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 335,329
Number of extensions: 511
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package