Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              17    3301
NP_001276049                                                           17    3301
NP_001276048                                                           17    3301
NP_001276050                                                           17    3301
NP_115602                                                              17    3301
XP_005251669                                                           17    3301
XP_005251668                                                           17    3301
XP_005251666                                                           17    3301
XP_005251665                                                           17    3301
XP_006714104                                                           17    3301
XP_005265800                                                           17    3301
XP_006714103                                                           17    3301
XP_006714102                                                           17    3301
NP_004663                                                              17    4312
XP_005246086                                                           17    4312
>NP_006197
          Length = 1089

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VMVLEVSSA 9
          V VLEVSSA
Sbjct: 82 VTVLEVSSA 90
>NP_001276049
          Length = 543

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VMVLEVSSA 9
           VM++EVSS+
Sbjct: 152 VMIIEVSSS 160
>NP_001276048
          Length = 543

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VMVLEVSSA 9
           VM++EVSS+
Sbjct: 152 VMIIEVSSS 160
>NP_001276050
          Length = 543

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VMVLEVSSA 9
           VM++EVSS+
Sbjct: 152 VMIIEVSSS 160
>NP_115602
          Length = 543

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VMVLEVSSA 9
           VM++EVSS+
Sbjct: 152 VMIIEVSSS 160
>XP_005251669
          Length = 543

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VMVLEVSSA 9
           VM++EVSS+
Sbjct: 152 VMIIEVSSS 160
>XP_005251668
          Length = 543

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VMVLEVSSA 9
           VM++EVSS+
Sbjct: 152 VMIIEVSSS 160
>XP_005251666
          Length = 543

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VMVLEVSSA 9
           VM++EVSS+
Sbjct: 152 VMIIEVSSS 160
>XP_005251665
          Length = 543

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VMVLEVSSA 9
           VM++EVSS+
Sbjct: 152 VMIIEVSSS 160
>XP_006714104
          Length = 832

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VMVLEVSSA 9
           V VLEVSSA
Sbjct: 107 VTVLEVSSA 115
>XP_005265800
          Length = 1089

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VMVLEVSSA 9
          V VLEVSSA
Sbjct: 82 VTVLEVSSA 90
>XP_006714103
          Length = 1111

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VMVLEVSSA 9
           V VLEVSSA
Sbjct: 104 VTVLEVSSA 112
>XP_006714102
          Length = 1114

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VMVLEVSSA 9
           V VLEVSSA
Sbjct: 107 VTVLEVSSA 115
>NP_004663
          Length = 1288

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   VMVLEVSSA 9
           V+VLEVSS+
Sbjct: 115 VVVLEVSSS 123
>XP_005246086
          Length = 1280

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   VMVLEVSSA 9
           V+VLEVSS+
Sbjct: 115 VVVLEVSSS 123
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.119    0.252 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 212,524
Number of extensions: 102
Number of successful extensions: 15
Number of sequences better than 10000.0: 15
Number of HSP's gapped: 15
Number of HSP's successfully gapped: 15
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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