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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115892                                                              17    4312
NP_001035269                                                           17    4312
XP_006710237                                                           16    7355
NP_001230894                                                           16    7355
NP_002784                                                              15    9605
NP_001001585                                                           15    9605
NP_001001583                                                           15    9605
NP_001001582                                                           15    9605
NP_001001579                                                           15    9605
NP_001001578                                                           15    9605
NP_001001577                                                           15    9605
NP_001001574                                                           15    9605
NP_001001572                                                           15    9605
NP_001001571                                                           15    9605
NP_001001570                                                           15    9605
NP_002597                                                              15    9605
NP_001138874                                                           15    9605
XP_005261189                                                           15    9605
XP_005273127                                                           15    9605
NP_001001584                                                           15    9605
NP_001001580                                                           15    9605
NP_001001575                                                           15    9605
NP_001001576                                                           15    9605
NP_001001581                                                           15    9605
NP_001001568                                                           15    9605
NP_001001573                                                           15    9605
NP_001001569                                                           15    9605
NP_001001567                                                           15    9605

>NP_115892
          Length = 340

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLTLTKMIL 9
           V+ LTKM+L
Sbjct: 246 VMKLTKMVL 254



>NP_001035269
          Length = 340

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLTLTKMIL 9
           V+ LTKM+L
Sbjct: 246 VMKLTKMVL 254



>XP_006710237
          Length = 274

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VLTLTKMIL 9
          VLT+T M+L
Sbjct: 14 VLTVTLMVL 22



>NP_001230894
          Length = 266

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VLTLTKMIL 9
          VLT+T M+L
Sbjct: 14 VLTVTLMVL 22



>NP_002784
          Length = 241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LTLTKMI 8
          LTLTK+I
Sbjct: 90 LTLTKII 96



>NP_001001585
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 243 MTLLKMIL 250



>NP_001001583
          Length = 567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 424 MTLLKMIL 431



>NP_001001582
          Length = 552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 409 MTLLKMIL 416



>NP_001001579
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 243 MTLLKMIL 250



>NP_001001578
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 348 MTLLKMIL 355



>NP_001001577
          Length = 459

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 316 MTLLKMIL 323



>NP_001001574
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 364 MTLLKMIL 371



>NP_001001572
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 243 MTLLKMIL 250



>NP_001001571
          Length = 492

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 349 MTLLKMIL 356



>NP_001001570
          Length = 540

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 397 MTLLKMIL 404



>NP_002597
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 450 MTLLKMIL 457



>NP_001138874
          Length = 922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LTLTKMIL 9
           LTLTK+++
Sbjct: 696 LTLTKLMI 703



>XP_005261189
          Length = 533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 450 MTLLKMIL 457



>XP_005273127
          Length = 421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  VLTLTKM 7
          VLTLTK+
Sbjct: 18 VLTLTKV 24



>NP_001001584
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 243 MTLLKMIL 250



>NP_001001580
          Length = 376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 233 MTLLKMIL 240



>NP_001001575
          Length = 433

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 290 MTLLKMIL 297



>NP_001001576
          Length = 376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 233 MTLLKMIL 240



>NP_001001581
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 383 MTLLKMIL 390



>NP_001001568
          Length = 466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 323 MTLLKMIL 330



>NP_001001573
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 243 MTLLKMIL 250



>NP_001001569
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 322 MTLLKMIL 329



>NP_001001567
          Length = 533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTLTKMIL 9
           +TL KMIL
Sbjct: 390 MTLLKMIL 397



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.339    0.147    0.351 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 254,311
Number of extensions: 252
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)