Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              19     665
NP_001263689                                                           19     665
NP_001119584                                                           19     665
NP_001119586                                                           19     665
NP_001263625                                                           19     665
NP_001119590                                                           19     665
NP_001263690                                                           19     665
NP_001119585                                                           19     665
NP_001263624                                                           19     665
NP_004225                                                              17    2528
XP_005259469                                                           17    2528
NP_001138552                                                           16    5631
XP_005257293                                                           16    5631
NP_001439                                                              16    7355
NP_055587                                                              16    7355
NP_001135869                                                           16    7355
NP_689976                                                              16    7355
NP_061836                                                              16    7355
NP_387505                                                              16    7355
XP_005261051                                                           16    7355
XP_006722652                                                           16    7355
XP_006722651                                                           16    7355
XP_006722650                                                           16    7355
XP_006722649                                                           16    7355
XP_006722648                                                           16    7355
XP_006722647                                                           16    7355
XP_006722646                                                           16    7355
XP_005258449                                                           16    7355
NP_937762                                                              15    9605
NP_001121190                                                           15    9605
NP_001171134                                                           15    9605
NP_000218                                                              15    9605
NP_060621                                                              15    9605
NP_001121189                                                           15    9605
NP_001171136                                                           15    9605
NP_998769                                                              15    9605
XP_006722801                                                           15    9605
XP_006722800                                                           15    9605
XP_005259606                                                           15    9605
XP_006712674                                                           15    9605
XP_006712673                                                           15    9605
XP_006712672                                                           15    9605
XP_005246722                                                           15    9605
NP_001171135                                                           15    9605
>NP_000537
          Length = 393

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLSQKTYQG 9
           V SQKTYQG
Sbjct: 97  VPSQKTYQG 105
>NP_001263689
          Length = 354

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VLSQKTYQG 9
          V SQKTYQG
Sbjct: 58 VPSQKTYQG 66
>NP_001119584
          Length = 393

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLSQKTYQG 9
           V SQKTYQG
Sbjct: 97  VPSQKTYQG 105
>NP_001119586
          Length = 341

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLSQKTYQG 9
           V SQKTYQG
Sbjct: 97  VPSQKTYQG 105
>NP_001263625
          Length = 302

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VLSQKTYQG 9
          V SQKTYQG
Sbjct: 58 VPSQKTYQG 66
>NP_001119590
          Length = 354

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VLSQKTYQG 9
          V SQKTYQG
Sbjct: 58 VPSQKTYQG 66
>NP_001263690
          Length = 354

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VLSQKTYQG 9
          V SQKTYQG
Sbjct: 58 VPSQKTYQG 66
>NP_001119585
          Length = 346

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLSQKTYQG 9
           V SQKTYQG
Sbjct: 97  VPSQKTYQG 105
>NP_001263624
          Length = 307

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VLSQKTYQG 9
          V SQKTYQG
Sbjct: 58 VPSQKTYQG 66
>NP_004225
          Length = 738

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKTYQG 9
           QKTYQG
Sbjct: 260 QKTYQG 265
>XP_005259469
          Length = 734

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKTYQG 9
           QKTYQG
Sbjct: 256 QKTYQG 261
>NP_001138552
          Length = 952

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LSQKTYQ 8
           LSQ TYQ
Sbjct: 629 LSQNTYQ 635
>XP_005257293
          Length = 920

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LSQKTYQ 8
           LSQ TYQ
Sbjct: 629 LSQNTYQ 635
>NP_001439
          Length = 556

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LSQKTYQG 9
           +SQK +QG
Sbjct: 333 VSQKVFQG 340
>NP_055587
          Length = 598

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QKTYQG 9
           QK+YQG
Sbjct: 224 QKSYQG 229
>NP_001135869
          Length = 600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QKTYQG 9
           QK+YQG
Sbjct: 224 QKSYQG 229
>NP_689976
          Length = 836

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QKTYQG 9
           QK+YQG
Sbjct: 225 QKSYQG 230
>NP_061836
          Length = 2320

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLSQKTYQ 8
            VLSQ+ YQ
Sbjct: 1086 VLSQEPYQ 1093
>NP_387505
          Length = 2269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLSQKTYQ 8
            VLSQ+ YQ
Sbjct: 1086 VLSQEPYQ 1093
>XP_005261051
          Length = 2242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLSQKTYQ 8
            VLSQ+ YQ
Sbjct: 1008 VLSQEPYQ 1015
>XP_006722652
          Length = 600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QKTYQG 9
           QK+YQG
Sbjct: 224 QKSYQG 229
>XP_006722651
          Length = 600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QKTYQG 9
           QK+YQG
Sbjct: 224 QKSYQG 229
>XP_006722650
          Length = 600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QKTYQG 9
           QK+YQG
Sbjct: 224 QKSYQG 229
>XP_006722649
          Length = 614

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QKTYQG 9
           QK+YQG
Sbjct: 240 QKSYQG 245
>XP_006722648
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QKTYQG 9
           QK+YQG
Sbjct: 240 QKSYQG 245
>XP_006722647
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QKTYQG 9
           QK+YQG
Sbjct: 240 QKSYQG 245
>XP_006722646
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QKTYQG 9
           QK+YQG
Sbjct: 240 QKSYQG 245
>XP_005258449
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QKTYQG 9
           QK+YQG
Sbjct: 240 QKSYQG 245
>NP_937762
          Length = 3333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    QKTYQG 9
            QKT+QG
Sbjct: 2010 QKTHQG 2015
>NP_001121190
          Length = 1668

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QKTYQG 9
           QKT+QG
Sbjct: 345 QKTHQG 350
>NP_001171134
          Length = 2446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LSQKTYQ 8
            LS+KT+Q
Sbjct: 1708 LSEKTFQ 1714
>NP_000218
          Length = 1724

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QKTYQG 9
           QKT+QG
Sbjct: 401 QKTHQG 406
>NP_060621
          Length = 2472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LSQKTYQ 8
            LS+KT+Q
Sbjct: 1708 LSEKTFQ 1714
>NP_001121189
          Length = 3277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    QKTYQG 9
            QKT+QG
Sbjct: 1954 QKTHQG 1959
>NP_001171136
          Length = 2446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LSQKTYQ 8
            LS+KT+Q
Sbjct: 1708 LSEKTFQ 1714
>NP_998769
          Length = 471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   SQKTYQ 8
           +QKTYQ
Sbjct: 109 TQKTYQ 114
>XP_006722801
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   SQKTYQ 8
           +QKTYQ
Sbjct: 119 TQKTYQ 124
>XP_006722800
          Length = 415

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   SQKTYQ 8
           +QKTYQ
Sbjct: 119 TQKTYQ 124
>XP_005259606
          Length = 481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   SQKTYQ 8
           +QKTYQ
Sbjct: 119 TQKTYQ 124
>XP_006712674
          Length = 2436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LSQKTYQ 8
            LS+KT+Q
Sbjct: 1672 LSEKTFQ 1678
>XP_006712673
          Length = 2441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LSQKTYQ 8
            LS+KT+Q
Sbjct: 1677 LSEKTFQ 1683
>XP_006712672
          Length = 2443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LSQKTYQ 8
            LS+KT+Q
Sbjct: 1679 LSEKTFQ 1685
>XP_005246722
          Length = 2472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LSQKTYQ 8
            LS+KT+Q
Sbjct: 1708 LSEKTFQ 1714
>NP_001171135
          Length = 2446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LSQKTYQ 8
            LS+KT+Q
Sbjct: 1708 LSEKTFQ 1714
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.123    0.322 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 502,082
Number of extensions: 751
Number of successful extensions: 44
Number of sequences better than 10000.0: 44
Number of HSP's gapped: 44
Number of HSP's successfully gapped: 44
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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