Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     509
NP_001075109                                                           20     509
NP_073585                                                              17    4312
NP_056098                                                              17    4312
NP_001073883                                                           16    5631
XP_006724219                                                           16    5631
XP_006724218                                                           16    5631
XP_006724217                                                           16    5631
XP_005267748                                                           16    5631
NP_689726                                                              16    5631
NP_001871                                                              16    7355
NP_001243022                                                           16    7355
NP_001243021                                                           16    7355
NP_001243019                                                           16    7355
NP_001243020                                                           16    7355
NP_003010                                                              16    7355
NP_001036068                                                           16    7355
NP_006847                                                              16    7355
XP_006723231                                                           16    7355
XP_005258877                                                           16    7355
XP_005258876                                                           16    7355
XP_006719266                                                           16    7355
XP_005268644                                                           16    7355
XP_006719265                                                           16    7355
NP_001123532                                                           16    7355
NP_054756                                                              16    7355
NP_001360                                                              15    9605
NP_001609                                                              15    9605
NP_060290                                                              15    9605
NP_001138501                                                           15    9605
NP_689691                                                              15    9605
NP_075068                                                              15    9605
NP_001254                                                              15    9605
NP_001268358                                                           15    9605
NP_612380                                                              15    9605
XP_005258616                                                           15    9605
XP_005258615                                                           15    9605
XP_005258567                                                           15    9605
XP_006722388                                                           15    9605
XP_005269285                                                           15    9605
XP_005269283                                                           15    9605
XP_006719754                                                           15    9605
XP_006719753                                                           15    9605
XP_005269281                                                           15    9605
XP_006717224                                                           15    9605
XP_006717221                                                           15    9605
XP_006717220                                                           15    9605
XP_006717219                                                           15    9605
XP_006717218                                                           15    9605
XP_006717217                                                           15    9605
XP_006717216                                                           15    9605
XP_006717215                                                           15    9605
XP_006717214                                                           15    9605
XP_005248319                                                           15    9605
XP_005262744                                                           15    9605
NP_001153332                                                           15    9605
NP_001153333                                                           15    9605
NP_055416                                                              15    9605
NP_789780                                                              15    9605
>NP_008835
          Length = 4128

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VLQQLIVAH 9
            VL+QLIVAH
Sbjct: 1713 VLEQLIVAH 1721
>NP_001075109
          Length = 4097

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VLQQLIVAH 9
            VL+QLIVAH
Sbjct: 1713 VLEQLIVAH 1721
>NP_073585
          Length = 1445

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QQLIVAH 9
           QQ++VAH
Sbjct: 593 QQMVVAH 599
>NP_056098
          Length = 675

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VLQQLIVAH 9
           VLQ L+V H
Sbjct: 221 VLQMLLVTH 229
>NP_001073883
          Length = 2028

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1  VLQQLIV 7
          VLQQLIV
Sbjct: 92 VLQQLIV 98
>XP_006724219
          Length = 1157

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLQQLIVAH 9
           +LQ+L+V H
Sbjct: 772 ILQRLLVEH 780
>XP_006724218
          Length = 1200

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLQQLIVAH 9
           +LQ+L+V H
Sbjct: 850 ILQRLLVEH 858
>XP_006724217
          Length = 1235

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLQQLIVAH 9
           +LQ+L+V H
Sbjct: 850 ILQRLLVEH 858
>XP_005267748
          Length = 1535

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1  VLQQLIV 7
          VLQQLIV
Sbjct: 92 VLQQLIV 98
>NP_689726
          Length = 1274

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLQQLIVAH 9
           +LQ+L+V H
Sbjct: 889 ILQRLLVEH 897
>NP_001871
          Length = 505

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LQQLIVAH 9
           L+QL++AH
Sbjct: 408 LKQLLLAH 415
>NP_001243022
          Length = 374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LQQLIVAH 9
           L+QL++AH
Sbjct: 350 LKQLLLAH 357
>NP_001243021
          Length = 447

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LQQLIVAH 9
           L+QL++AH
Sbjct: 350 LKQLLLAH 357
>NP_001243019
          Length = 505

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LQQLIVAH 9
           L+QL++AH
Sbjct: 408 LKQLLLAH 415
>NP_001243020
          Length = 487

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LQQLIVAH 9
           L+QL++AH
Sbjct: 390 LKQLLLAH 397
>NP_003010
          Length = 375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQQLIVA 8
           LQQL+VA
Sbjct: 300 LQQLVVA 306
>NP_001036068
          Length = 1690

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLQQLIVAH 9
           VL+Q ++AH
Sbjct: 450 VLEQSVLAH 458
>NP_006847
          Length = 483

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LQQLIVAH 9
           L+QL++AH
Sbjct: 388 LKQLLLAH 395
>XP_006723231
          Length = 736

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQQLIVA 8
           LQQL+VA
Sbjct: 322 LQQLVVA 328
>XP_005258877
          Length = 736

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQQLIVA 8
           LQQL+VA
Sbjct: 322 LQQLVVA 328
>XP_005258876
          Length = 818

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQQLIVA 8
           LQQL+VA
Sbjct: 404 LQQLVVA 410
>XP_006719266
          Length = 451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LQQLIVAH 9
           L+QL++AH
Sbjct: 356 LKQLLLAH 363
>XP_005268644
          Length = 483

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LQQLIVAH 9
           L+QL++AH
Sbjct: 388 LKQLLLAH 395
>XP_006719265
          Length = 483

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LQQLIVAH 9
           L+QL++AH
Sbjct: 388 LKQLLLAH 395
>NP_001123532
          Length = 462

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LQQLIVAH 9
           L+QL++AH
Sbjct: 367 LKQLLLAH 374
>NP_054756
          Length = 736

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LQQLIVA 8
           LQQL+VA
Sbjct: 322 LQQLVVA 328
>NP_001360
          Length = 4624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           ++QLIV H
Sbjct: 770 IEQLIVPH 777
>NP_001609
          Length = 1014

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           LQ+L +AH
Sbjct: 469 LQELFLAH 476
>NP_060290
          Length = 876

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           L QL+V+H
Sbjct: 303 LSQLLVSH 310
>NP_001138501
          Length = 1392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    QQLIVAH 9
            QQL+ AH
Sbjct: 1315 QQLVYAH 1321
>NP_689691
          Length = 569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LQQLIVAH 9
           L QLI+ H
Sbjct: 139 LSQLIITH 146
>NP_075068
          Length = 1146

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VLQQLIV 7
           +LQQL+V
Sbjct: 969 ILQQLVV 975
>NP_001254
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VLQQLIV 7
           VLQQL+V
Sbjct: 426 VLQQLLV 432
>NP_001268358
          Length = 432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           L QL++AH
Sbjct: 240 LSQLLLAH 247
>NP_612380
          Length = 432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           L QL++AH
Sbjct: 240 LSQLLLAH 247
>XP_005258616
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LQQLIVAH 9
           L QLI+ H
Sbjct: 96  LSQLIITH 103
>XP_005258615
          Length = 570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LQQLIVAH 9
           L QLI+ H
Sbjct: 140 LSQLIITH 147
>XP_005258567
          Length = 1036

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VLQQLIVA 8
           VLQ LI+A
Sbjct: 770 VLQDLIIA 777
>XP_006722388
          Length = 1511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    QQLIVAH 9
            QQL+ AH
Sbjct: 1434 QQLVYAH 1440
>XP_005269285
          Length = 432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           L QL++AH
Sbjct: 240 LSQLLLAH 247
>XP_005269283
          Length = 432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           L QL++AH
Sbjct: 240 LSQLLLAH 247
>XP_006719754
          Length = 432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           L QL++AH
Sbjct: 240 LSQLLLAH 247
>XP_006719753
          Length = 432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           L QL++AH
Sbjct: 240 LSQLLLAH 247
>XP_005269281
          Length = 432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           L QL++AH
Sbjct: 240 LSQLLLAH 247
>XP_006717224
          Length = 915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           L QL+V+H
Sbjct: 355 LSQLLVSH 362
>XP_006717221
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           L QL+V+H
Sbjct: 355 LSQLLVSH 362
>XP_006717220
          Length = 825

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           L QL+V+H
Sbjct: 355 LSQLLVSH 362
>XP_006717219
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           L QL+V+H
Sbjct: 355 LSQLLVSH 362
>XP_006717218
          Length = 877

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           L QL+V+H
Sbjct: 303 LSQLLVSH 310
>XP_006717217
          Length = 905

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           L QL+V+H
Sbjct: 331 LSQLLVSH 338
>XP_006717216
          Length = 916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           L QL+V+H
Sbjct: 355 LSQLLVSH 362
>XP_006717215
          Length = 928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           L QL+V+H
Sbjct: 355 LSQLLVSH 362
>XP_006717214
          Length = 929

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           L QL+V+H
Sbjct: 355 LSQLLVSH 362
>XP_005248319
          Length = 4609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQQLIVAH 9
           ++QLIV H
Sbjct: 755 IEQLIVPH 762
>XP_005262744
          Length = 421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VLQQLIV 7
           VLQQL+V
Sbjct: 386 VLQQLLV 392
>NP_001153332
          Length = 569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LQQLIVAH 9
           L QLI+ H
Sbjct: 139 LSQLIITH 146
>NP_001153333
          Length = 569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LQQLIVAH 9
           L QLI+ H
Sbjct: 139 LSQLIITH 146
>NP_055416
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LQQLIVAH 9
           +Q+L++AH
Sbjct: 359 MQELLMAH 366
>NP_789780
          Length = 1043

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VLQQLIVA 8
           VLQ LI+A
Sbjct: 770 VLQDLIIA 777
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.338    0.143    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 412,230
Number of extensions: 583
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package