Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              18    1482
NP_653080                                                              18    1482
XP_005267292                                                           18    1482
XP_005267291                                                           18    1482
XP_005267290                                                           18    1482
NP_001135444                                                           17    3301
NP_004288                                                              17    3301
NP_002058                                                              17    3301
NP_002063                                                              17    3301
NP_653297                                                              17    4312
XP_006711224                                                           17    4312
XP_006711223                                                           17    4312
XP_006711222                                                           17    4312
XP_006711221                                                           17    4312
XP_006711220                                                           17    4312
NP_004583                                                              16    5631
NP_001248340                                                           16    5631
NP_065075                                                              16    5631
XP_006719621                                                           16    5631
XP_005246749                                                           16    5631
XP_005246746                                                           16    5631
NP_001120729                                                           16    5631
NP_055873                                                              16    7355
NP_036363                                                              16    7355
NP_001007258                                                           16    7355
NP_056950                                                              16    7355
XP_006719854                                                           16    7355
XP_006719853                                                           16    7355
XP_005246055                                                           16    7355
XP_006710943                                                           16    7355
XP_006710942                                                           16    7355
XP_006710941                                                           16    7355
XP_005246054                                                           16    7355
XP_005246053                                                           16    7355
XP_006710940                                                           16    7355
XP_005246052                                                           16    7355
XP_005246051                                                           16    7355
XP_005246050                                                           16    7355
XP_005246049                                                           16    7355
NP_001274141                                                           15    9605
NP_001123481                                                           15    9605
NP_078838                                                              15    9605
NP_872431                                                              15    9605
NP_065867                                                              15    9605
NP_001116291                                                           15    9605
XP_006712069                                                           15    9605
XP_006712068                                                           15    9605
XP_005262670                                                           15    9605
XP_005246008                                                           15    9605
XP_005246007                                                           15    9605
>NP_005091
          Length = 1782

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           V LSEYDAV
Sbjct: 847 VPLSEYDAV 855
>NP_653080
          Length = 1684

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           V LSEYDAV
Sbjct: 749 VPLSEYDAV 757
>XP_005267292
          Length = 1677

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           V LSEYDAV
Sbjct: 742 VPLSEYDAV 750
>XP_005267291
          Length = 1684

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           V LSEYDAV
Sbjct: 749 VPLSEYDAV 757
>XP_005267290
          Length = 1782

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           V LSEYDAV
Sbjct: 847 VPLSEYDAV 855
>NP_001135444
          Length = 165

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLSEYDAV 9
           LL+EYDA+
Sbjct: 111 LLAEYDAL 118
>NP_004288
          Length = 355

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VLLSEYDAV 9
           V LSEYD V
Sbjct: 226 VALSEYDQV 234
>NP_002058
          Length = 359

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VLLSEYDAV 9
           V LSEYD V
Sbjct: 230 VALSEYDQV 238
>NP_002063
          Length = 359

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VLLSEYDAV 9
           V LSEYD V
Sbjct: 230 VALSEYDQV 238
>NP_653297
          Length = 1012

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLLS+YD +
Sbjct: 534 VLLSKYDTL 542
>XP_006711224
          Length = 796

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLLS+YD +
Sbjct: 534 VLLSKYDTL 542
>XP_006711223
          Length = 913

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLLS+YD +
Sbjct: 534 VLLSKYDTL 542
>XP_006711222
          Length = 970

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLLS+YD +
Sbjct: 492 VLLSKYDTL 500
>XP_006711221
          Length = 976

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLLS+YD +
Sbjct: 534 VLLSKYDTL 542
>XP_006711220
          Length = 1012

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLLS+YD +
Sbjct: 534 VLLSKYDTL 542
>NP_004583
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  LSEYDA 8
          LSEYDA
Sbjct: 83 LSEYDA 88
>NP_001248340
          Length = 1003

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  LSEYDA 8
          LSEYDA
Sbjct: 83 LSEYDA 88
>NP_065075
          Length = 831

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LSEYDAV 9
           L EYDAV
Sbjct: 489 LEEYDAV 495
>XP_006719621
          Length = 874

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  LSEYDA 8
          LSEYDA
Sbjct: 83 LSEYDA 88
>XP_005246749
          Length = 381

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  LSEYDAV 9
          L EYDAV
Sbjct: 39 LEEYDAV 45
>XP_005246746
          Length = 898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LSEYDAV 9
           L EYDAV
Sbjct: 556 LEEYDAV 562
>NP_001120729
          Length = 831

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LSEYDAV 9
           L EYDAV
Sbjct: 489 LEEYDAV 495
>NP_055873
          Length = 1905

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VLLSEYDA 8
            + +SEYDA
Sbjct: 1630 IQMSEYDA 1637
>NP_036363
          Length = 1718

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLL+EY+ +
Sbjct: 891 VLLNEYNGI 899
>NP_001007258
          Length = 1481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLL+EY+ +
Sbjct: 690 VLLNEYNGI 698
>NP_056950
          Length = 1682

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLL+EY+ +
Sbjct: 891 VLLNEYNGI 899
>XP_006719854
          Length = 1550

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VLLSEYDA 8
            + +SEYDA
Sbjct: 1275 IQMSEYDA 1282
>XP_006719853
          Length = 1809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VLLSEYDA 8
            + +SEYDA
Sbjct: 1534 IQMSEYDA 1541
>XP_005246055
          Length = 1481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLL+EY+ +
Sbjct: 690 VLLNEYNGI 698
>XP_006710943
          Length = 1517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLL+EY+ +
Sbjct: 690 VLLNEYNGI 698
>XP_006710942
          Length = 1517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLL+EY+ +
Sbjct: 690 VLLNEYNGI 698
>XP_006710941
          Length = 1517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLL+EY+ +
Sbjct: 690 VLLNEYNGI 698
>XP_005246054
          Length = 1517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLL+EY+ +
Sbjct: 690 VLLNEYNGI 698
>XP_005246053
          Length = 1644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLL+EY+ +
Sbjct: 817 VLLNEYNGI 825
>XP_006710940
          Length = 1682

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLL+EY+ +
Sbjct: 891 VLLNEYNGI 899
>XP_005246052
          Length = 1692

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLL+EY+ +
Sbjct: 901 VLLNEYNGI 909
>XP_005246051
          Length = 1717

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLL+EY+ +
Sbjct: 890 VLLNEYNGI 898
>XP_005246050
          Length = 1718

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLL+EY+ +
Sbjct: 891 VLLNEYNGI 899
>XP_005246049
          Length = 1728

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLL+EY+ +
Sbjct: 901 VLLNEYNGI 909
>NP_001274141
          Length = 929

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLL+ YD++
Sbjct: 696 VLLNVYDSI 704
>NP_001123481
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VLLSEYDAV 9
           VLL+ YD +
Sbjct: 377 VLLTHYDMI 385
>NP_078838
          Length = 1094

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VLLSEYD 7
           VLLS YD
Sbjct: 842 VLLSAYD 848
>NP_872431
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VLLSEYDAV 9
           VLL+ YD +
Sbjct: 377 VLLTHYDMI 385
>NP_065867
          Length = 1029

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLL+ YD++
Sbjct: 796 VLLNVYDSI 804
>NP_001116291
          Length = 1028

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLL+ YD++
Sbjct: 796 VLLNVYDSI 804
>XP_006712069
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VLLSEYDAV 9
           VLL+ YD +
Sbjct: 377 VLLTHYDMI 385
>XP_006712068
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VLLSEYDAV 9
           VLL+ YD +
Sbjct: 377 VLLTHYDMI 385
>XP_005262670
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VLLSEYDAV 9
           VLL+ YD +
Sbjct: 377 VLLTHYDMI 385
>XP_005246008
          Length = 984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLL+ YD++
Sbjct: 796 VLLNVYDSI 804
>XP_005246007
          Length = 985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLLSEYDAV 9
           VLL+ YD++
Sbjct: 796 VLLNVYDSI 804
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.317    0.136    0.341 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 453,452
Number of extensions: 560
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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