Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              17    2528
NP_671714                                                              17    2528
XP_006715890                                                           17    2528
XP_005250160                                                           17    2528
XP_005250159                                                           17    2528
NP_116271                                                              17    3301
NP_006793                                                              17    3301
XP_005274106                                                           17    3301
XP_005274105                                                           17    3301
XP_005270447                                                           17    3301
NP_056969                                                              17    3301
NP_899236                                                              16    5631
NP_056363                                                              16    5631
NP_001138241                                                           16    5631
NP_001138242                                                           16    5631
NP_055994                                                              16    5631
NP_001138586                                                           16    5631
NP_001271266                                                           16    5631
XP_006715232                                                           16    5631
XP_005249382                                                           16    5631
XP_005249381                                                           16    5631
XP_005249380                                                           16    5631
XP_005249379                                                           16    5631
XP_005249377                                                           16    5631
XP_005249376                                                           16    5631
XP_005249375                                                           16    5631
XP_005249374                                                           16    5631
XP_005249373                                                           16    5631
XP_005249372                                                           16    5631
XP_005249371                                                           16    5631
XP_005249370                                                           16    5631
XP_005249369                                                           16    5631
XP_005249368                                                           16    5631
XP_005249367                                                           16    5631
NP_001035362                                                           15    9605
NP_056993                                                              15    9605
NP_001099129                                                           15    9605
NP_001272376                                                           15    9605
NP_001272374                                                           15    9605
NP_001272373                                                           15    9605
NP_001008783                                                           15    9605
NP_055842                                                              15    9605
NP_001272377                                                           15    9605
XP_006726663                                                           15    9605
XP_006726662                                                           15    9605
XP_006726661                                                           15    9605
XP_006726660                                                           15    9605
XP_006726659                                                           15    9605
XP_006726658                                                           15    9605
XP_006725291                                                           15    9605
XP_006725290                                                           15    9605
XP_006725289                                                           15    9605
XP_006725288                                                           15    9605
XP_006725287                                                           15    9605
XP_006725286                                                           15    9605
XP_005255233                                                           15    9605
XP_006720928                                                           15    9605
XP_005255231                                                           15    9605
XP_005255230                                                           15    9605
XP_006710416                                                           15    9605
XP_006710415                                                           15    9605
XP_005270511                                                           15    9605
>NP_005742
          Length = 3907

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLLQKASER 9
            VL QKASER
Sbjct: 3528 VLPQKASER 3536
>NP_671714
          Length = 3899

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLLQKASER 9
            VL QKASER
Sbjct: 3520 VLPQKASER 3528
>XP_006715890
          Length = 3860

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLLQKASER 9
            VL QKASER
Sbjct: 3481 VLPQKASER 3489
>XP_005250160
          Length = 3939

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLLQKASER 9
            VL QKASER
Sbjct: 3560 VLPQKASER 3568
>XP_005250159
          Length = 3952

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLLQKASER 9
            VL QKASER
Sbjct: 3573 VLPQKASER 3581
>NP_116271
          Length = 399

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VLLQKASER 9
           VLLQKA E+
Sbjct: 265 VLLQKAMEK 273
>NP_006793
          Length = 501

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LQKASER 9
           LQKASER
Sbjct: 464 LQKASER 470
>XP_005274106
          Length = 1685

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LLQKASER 9
           LLQK SER
Sbjct: 664 LLQKTSER 671
>XP_005274105
          Length = 1686

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LLQKASER 9
           LLQK SER
Sbjct: 664 LLQKTSER 671
>XP_005270447
          Length = 448

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LQKASER 9
           LQKASER
Sbjct: 411 LQKASER 417
>NP_056969
          Length = 1555

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LLQKASER 9
           LLQK SER
Sbjct: 664 LLQKTSER 671
>NP_899236
          Length = 5497

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 3209 ILLQKAEE 3216
>NP_056363
          Length = 5171

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 2883 ILLQKAEE 2890
>NP_001138241
          Length = 5675

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 3387 ILLQKAEE 3394
>NP_001138242
          Length = 5537

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 3249 ILLQKAEE 3256
>NP_055994
          Length = 1297

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLQKASER 9
           LL+KASE+
Sbjct: 732 LLEKASEK 739
>NP_001138586
          Length = 1236

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLQKASER 9
           LL+KASE+
Sbjct: 671 LLEKASEK 678
>NP_001271266
          Length = 1197

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLQKASER 9
           LL+KASE+
Sbjct: 632 LLEKASEK 639
>XP_006715232
          Length = 7498

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 5295 ILLQKAEE 5302
>XP_005249382
          Length = 5732

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 3420 ILLQKAEE 3427
>XP_005249381
          Length = 7281

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 4969 ILLQKAEE 4976
>XP_005249380
          Length = 7607

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 5295 ILLQKAEE 5302
>XP_005249379
          Length = 7633

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 5321 ILLQKAEE 5328
>XP_005249377
          Length = 7640

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 5328 ILLQKAEE 5335
>XP_005249376
          Length = 7647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 5335 ILLQKAEE 5342
>XP_005249375
          Length = 7680

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 5368 ILLQKAEE 5375
>XP_005249374
          Length = 7709

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 5506 ILLQKAEE 5513
>XP_005249373
          Length = 7723

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 5411 ILLQKAEE 5418
>XP_005249372
          Length = 7785

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 5473 ILLQKAEE 5480
>XP_005249371
          Length = 7788

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 5506 ILLQKAEE 5513
>XP_005249370
          Length = 7794

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 5506 ILLQKAEE 5513
>XP_005249369
          Length = 7797

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 5485 ILLQKAEE 5492
>XP_005249368
          Length = 7812

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 5506 ILLQKAEE 5513
>XP_005249367
          Length = 7818

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            +LLQKA E
Sbjct: 5506 ILLQKAEE 5513
>NP_001035362
          Length = 1762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VLLQKAS 7
            VL+QKAS
Sbjct: 1477 VLMQKAS 1483
>NP_056993
          Length = 2371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    VLLQKASE 8
            VLLQ ASE
Sbjct: 1528 VLLQLASE 1535
>NP_001099129
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKASER 9
           QKASER
Sbjct: 510 QKASER 515
>NP_001272376
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 607 VELQKASE 614
>NP_001272374
          Length = 760

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 594 VELQKASE 601
>NP_001272373
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 595 VELQKASE 602
>NP_001008783
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VLLQKAS 7
           VL+QKAS
Sbjct: 173 VLIQKAS 179
>NP_055842
          Length = 788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 622 VELQKASE 629
>NP_001272377
          Length = 697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 531 VELQKASE 538
>XP_006726663
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 595 VELQKASE 602
>XP_006726662
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 607 VELQKASE 614
>XP_006726661
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 613 VELQKASE 620
>XP_006726660
          Length = 788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 622 VELQKASE 629
>XP_006726659
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 631 VELQKASE 638
>XP_006726658
          Length = 806

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 640 VELQKASE 647
>XP_006725291
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 595 VELQKASE 602
>XP_006725290
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 607 VELQKASE 614
>XP_006725289
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 613 VELQKASE 620
>XP_006725288
          Length = 788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 622 VELQKASE 629
>XP_006725287
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 631 VELQKASE 638
>XP_006725286
          Length = 806

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 640 VELQKASE 647
>XP_005255233
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 607 VELQKASE 614
>XP_006720928
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 613 VELQKASE 620
>XP_005255231
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 631 VELQKASE 638
>XP_005255230
          Length = 806

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VLLQKASE 8
           V LQKASE
Sbjct: 640 VELQKASE 647
>XP_006710416
          Length = 304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKASER 9
           QKASER
Sbjct: 190 QKASER 195
>XP_006710415
          Length = 304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKASER 9
           QKASER
Sbjct: 190 QKASER 195
>XP_005270511
          Length = 304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKASER 9
           QKASER
Sbjct: 190 QKASER 195
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.124    0.280 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 341,129
Number of extensions: 474
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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