Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_060719                                                              18    1482
NP_001258968                                                           18    1482
NP_001011649                                                           18    1482
NP_001185761                                                           18    1482
NP_071754                                                              18    1482
NP_001185763                                                           18    1482
NP_001002810                                                           18    1482
NP_055459                                                              18    1482
NP_001182189                                                           18    1482
NP_001002812                                                           18    1482
NP_001182190                                                           18    1482
XP_006717248                                                           18    1482
XP_006717247                                                           18    1482
XP_006717246                                                           18    1482
XP_006717245                                                           18    1482
XP_006717244                                                           18    1482
XP_006717243                                                           18    1482
XP_006717242                                                           18    1482
XP_006711719                                                           18    1482
XP_006711717                                                           18    1482
XP_006711716                                                           18    1482
XP_006711715                                                           18    1482
XP_006711714                                                           18    1482
XP_006711713                                                           18    1482
XP_006711710                                                           18    1482
XP_006711709                                                           18    1482
NP_689562                                                              16    5631
NP_001254651                                                           16    7355
NP_008878                                                              16    7355
NP_001275953                                                           16    7355
NP_001275950                                                           16    7355
NP_001275949                                                           16    7355
NP_659464                                                              16    7355
NP_060350                                                              16    7355
XP_005248961                                                           16    7355
XP_005265822                                                           16    7355
XP_005264448                                                           16    7355
XP_005264447                                                           16    7355
XP_005264446                                                           16    7355
NP_005532                                                              15    9605
NP_001017915                                                           15    9605
NP_001171809                                                           15    9605
NP_001098713                                                           15    9605
NP_065817                                                              15    9605
NP_055383                                                              15    9605
NP_659496                                                              15    9605
NP_005427                                                              15    9605
XP_006721226                                                           15    9605
XP_006721225                                                           15    9605
XP_006721224                                                           15    9605
XP_005268418                                                           15    9605
XP_005268417                                                           15    9605
XP_005268416                                                           15    9605
NP_061161                                                              15    9605
>NP_060719
          Length = 1893

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKVEVESL
Sbjct: 106 LKVEVESL 113
>NP_001258968
          Length = 1663

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKVEVESL
Sbjct: 106 LKVEVESL 113
>NP_001011649
          Length = 1814

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKVEVESL
Sbjct: 106 LKVEVESL 113
>NP_001185761
          Length = 2240

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKVEVESL
Sbjct: 117 LKVEVESL 124
>NP_071754
          Length = 310

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKVEVESL
Sbjct: 188 LKVEVESL 195
>NP_001185763
          Length = 2362

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LKVEVESL 9
          LKVEVESL
Sbjct: 51 LKVEVESL 58
>NP_001002810
          Length = 173

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LKVEVESL 9
          LKVEVESL
Sbjct: 51 LKVEVESL 58
>NP_055459
          Length = 2346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LKVEVESL 9
          LKVEVESL
Sbjct: 51 LKVEVESL 58
>NP_001182189
          Length = 141

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LKVEVESL 9
          LKVEVESL
Sbjct: 19 LKVEVESL 26
>NP_001002812
          Length = 969

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LKVEVESL 9
          LKVEVESL
Sbjct: 51 LKVEVESL 58
>NP_001182190
          Length = 176

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LKVEVESL 9
          LKVEVESL
Sbjct: 54 LKVEVESL 61
>XP_006717248
          Length = 1664

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKVEVESL
Sbjct: 106 LKVEVESL 113
>XP_006717247
          Length = 1670

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKVEVESL
Sbjct: 106 LKVEVESL 113
>XP_006717246
          Length = 1820

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKVEVESL
Sbjct: 106 LKVEVESL 113
>XP_006717245
          Length = 1861

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKVEVESL
Sbjct: 106 LKVEVESL 113
>XP_006717244
          Length = 1867

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKVEVESL
Sbjct: 106 LKVEVESL 113
>XP_006717243
          Length = 1889

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKVEVESL
Sbjct: 96  LKVEVESL 103
>XP_006717242
          Length = 1898

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKVEVESL
Sbjct: 105 LKVEVESL 112
>XP_006711719
          Length = 2302

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKVEVESL
Sbjct: 117 LKVEVESL 124
>XP_006711717
          Length = 2385

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKVEVESL
Sbjct: 117 LKVEVESL 124
>XP_006711716
          Length = 2411

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKVEVESL
Sbjct: 117 LKVEVESL 124
>XP_006711715
          Length = 2428

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LKVEVESL 9
          LKVEVESL
Sbjct: 51 LKVEVESL 58
>XP_006711714
          Length = 2429

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LKVEVESL 9
          LKVEVESL
Sbjct: 51 LKVEVESL 58
>XP_006711713
          Length = 2432

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LKVEVESL 9
          LKVEVESL
Sbjct: 54 LKVEVESL 61
>XP_006711710
          Length = 2494

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKVEVESL
Sbjct: 117 LKVEVESL 124
>XP_006711709
          Length = 2495

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKVEVESL
Sbjct: 117 LKVEVESL 124
>NP_689562
          Length = 295

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  LKVEVESL 9
          L+VE+ESL
Sbjct: 65 LQVEIESL 72
>NP_001254651
          Length = 610

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKV+VE+L
Sbjct: 453 LKVDVEAL 460
>NP_008878
          Length = 671

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKV+VE+L
Sbjct: 514 LKVDVEAL 521
>NP_001275953
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKVEVESL 9
           LKVE+E L
Sbjct: 111 LKVEIEHL 118
>NP_001275950
          Length = 758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKVEVESL 9
           LKVE+E L
Sbjct: 604 LKVEIEHL 611
>NP_001275949
          Length = 797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKVEVESL 9
           LKVE+E L
Sbjct: 643 LKVEIEHL 650
>NP_659464
          Length = 814

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKVEVESL 9
           LKVE+E L
Sbjct: 660 LKVEIEHL 667
>NP_060350
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KVEVESL 9
           KVEVES+
Sbjct: 475 KVEVESI 481
>XP_005248961
          Length = 842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKVEVESL 9
           LKVE+E L
Sbjct: 660 LKVEIEHL 667
>XP_005265822
          Length = 663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LKVEVESL 9
           LKV+VE+L
Sbjct: 629 LKVDVEAL 636
>XP_005264448
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KVEVESL 9
           KVEVES+
Sbjct: 475 KVEVESI 481
>XP_005264447
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KVEVESL 9
           KVEVES+
Sbjct: 475 KVEVESI 481
>XP_005264446
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KVEVESL 9
           KVEVES+
Sbjct: 475 KVEVESI 481
>NP_005532
          Length = 1188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LKVEVES 8
           LKV+VES
Sbjct: 315 LKVDVES 321
>NP_001017915
          Length = 1189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LKVEVES 8
           LKV+VES
Sbjct: 316 LKVDVES 322
>NP_001171809
          Length = 1148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLKVEVESL 9
           V+KVE++ L
Sbjct: 114 VIKVEIKDL 122
>NP_001098713
          Length = 1101

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLKVEVESL 9
           V+KVE++ L
Sbjct: 114 VIKVEIKDL 122
>NP_065817
          Length = 1100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLKVEVESL 9
           V+KVE++ L
Sbjct: 114 VIKVEIKDL 122
>NP_055383
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VLKVEVE 7
           VLKVEV+
Sbjct: 98  VLKVEVD 104
>NP_659496
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKVEVESL 9
           LKVEVE +
Sbjct: 906 LKVEVEEV 913
>NP_005427
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  VLKVEVES 8
          VLK+E+E+
Sbjct: 72 VLKIELET 79
>XP_006721226
          Length = 756

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKVEVESL 9
           LKVEVE +
Sbjct: 578 LKVEVEEV 585
>XP_006721225
          Length = 1057

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKVEVESL 9
           LKVEVE +
Sbjct: 879 LKVEVEEV 886
>XP_006721224
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKVEVESL 9
           LKVEVE +
Sbjct: 906 LKVEVEEV 913
>XP_005268418
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKVEVESL 9
           LKVE+E L
Sbjct: 279 LKVELEQL 286
>XP_005268417
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKVEVESL 9
           LKVE+E L
Sbjct: 279 LKVELEQL 286
>XP_005268416
          Length = 511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKVEVESL 9
           LKVE+E L
Sbjct: 285 LKVELEQL 292
>NP_061161
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKVEVESL 9
           LKVE+E L
Sbjct: 279 LKVELEQL 286
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.131    0.287 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 338,150
Number of extensions: 410
Number of successful extensions: 54
Number of sequences better than 10000.0: 54
Number of HSP's gapped: 54
Number of HSP's successfully gapped: 54
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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