Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1135
NP_001185763                                                           18    1135
NP_055459                                                              18    1135
XP_006726436                                                           18    1135
XP_006726410                                                           18    1135
XP_006711784                                                           18    1135
XP_006711719                                                           18    1135
XP_006711718                                                           18    1135
XP_006711717                                                           18    1135
XP_006711716                                                           18    1135
XP_006711715                                                           18    1135
XP_006711714                                                           18    1135
XP_006711713                                                           18    1135
XP_006711712                                                           18    1135
XP_006711711                                                           18    1135
XP_006711710                                                           18    1135
XP_006711709                                                           18    1135
XP_005277503                                                           18    1135
XP_005273038                                                           18    1135
XP_006711708                                                           18    1135
XP_005277500                                                           18    1135
XP_006711707                                                           18    1135
XP_005277499                                                           18    1135
XP_006711706                                                           18    1135
XP_006711705                                                           18    1135
XP_006711164                                                           18    1135
XP_005276114                                                           18    1135
XP_006710122                                                           18    1135
NP_006209                                                              17    3301
XP_006713721                                                           17    3301
XP_006723210                                                           17    4312
NP_037366                                                              17    4312
NP_001248344                                                           16    7355
NP_694534                                                              16    7355
NP_008871                                                              16    7355
NP_821078                                                              16    7355
NP_001248343                                                           16    7355
XP_006719213                                                           16    7355
XP_006719212                                                           16    7355
NP_001244068                                                           15    9605
NP_000076                                                              15    9605
NP_001159417                                                           15    9605
NP_001008781                                                           15    9605
NP_001254                                                              15    9605
NP_004061                                                              15    9605
XP_005262744                                                           15    9605
XP_005245790                                                           15    9605
XP_006710132                                                           15    9605
NP_001036169                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2218 VLKKARTNL 2226
>NP_001185763
          Length = 2362

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2324 VLKKARTNL 2332
>NP_055459
          Length = 2346

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2324 VLKKARTNL 2332
>XP_006726436
          Length = 178

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLKKAMTNL 9
           VLKKA TNL
Sbjct: 102 VLKKARTNL 110
>XP_006726410
          Length = 2087

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2065 VLKKARTNL 2073
>XP_006711784
          Length = 178

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLKKAMTNL 9
           VLKKA TNL
Sbjct: 102 VLKKARTNL 110
>XP_006711719
          Length = 2302

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2280 VLKKARTNL 2288
>XP_006711718
          Length = 1436

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 1331 VLKKARTNL 1339
>XP_006711717
          Length = 2385

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2280 VLKKARTNL 2288
>XP_006711716
          Length = 2411

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2389 VLKKARTNL 2397
>XP_006711715
          Length = 2428

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2323 VLKKARTNL 2331
>XP_006711714
          Length = 2429

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2324 VLKKARTNL 2332
>XP_006711713
          Length = 2432

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2327 VLKKARTNL 2335
>XP_006711712
          Length = 2473

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2368 VLKKARTNL 2376
>XP_006711711
          Length = 2482

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2377 VLKKARTNL 2385
>XP_006711710
          Length = 2494

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2389 VLKKARTNL 2397
>XP_006711709
          Length = 2495

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2390 VLKKARTNL 2398
>XP_005277503
          Length = 2498

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2487 VLKKARTNL 2495
>XP_005273038
          Length = 2509

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2487 VLKKARTNL 2495
>XP_006711708
          Length = 2512

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2407 VLKKARTNL 2415
>XP_005277500
          Length = 2525

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2487 VLKKARTNL 2495
>XP_006711707
          Length = 2553

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2448 VLKKARTNL 2456
>XP_005277499
          Length = 2561

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2487 VLKKARTNL 2495
>XP_006711706
          Length = 2591

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2486 VLKKARTNL 2494
>XP_006711705
          Length = 2592

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2487 VLKKARTNL 2495
>XP_006711164
          Length = 2087

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VLKKAMTNL 9
            VLKKA TNL
Sbjct: 2065 VLKKARTNL 2073
>XP_005276114
          Length = 134

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VLKKAMTNL 9
          VLKKA TNL
Sbjct: 72 VLKKARTNL 80
>XP_006710122
          Length = 126

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLKKAMTNL 9
           VLKKA TNL
Sbjct: 102 VLKKARTNL 110
>NP_006209
          Length = 1068

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VLKKAMTN 8
           +LKKA+TN
Sbjct: 653 LLKKALTN 660
>XP_006713721
          Length = 1068

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VLKKAMTN 8
           +LKKA+TN
Sbjct: 653 LLKKALTN 660
>XP_006723210
          Length = 192

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VLKKAMTNL 9
          +L KA+TNL
Sbjct: 69 ILLKALTNL 77
>NP_037366
          Length = 218

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VLKKAMTNL 9
          +L KA+TNL
Sbjct: 69 ILLKALTNL 77
>NP_001248344
          Length = 753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   KAMTNL 9
           KAMTNL
Sbjct: 585 KAMTNL 590
>NP_694534
          Length = 750

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   KAMTNL 9
           KAMTNL
Sbjct: 582 KAMTNL 587
>NP_008871
          Length = 763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   KAMTNL 9
           KAMTNL
Sbjct: 595 KAMTNL 600
>NP_821078
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   KAMTNL 9
           KAMTNL
Sbjct: 209 KAMTNL 214
>NP_001248343
          Length = 642

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   KAMTNL 9
           KAMTNL
Sbjct: 474 KAMTNL 479
>XP_006719213
          Length = 750

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   KAMTNL 9
           KAMTNL
Sbjct: 582 KAMTNL 587
>XP_006719212
          Length = 750

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   KAMTNL 9
           KAMTNL
Sbjct: 582 KAMTNL 587
>NP_001244068
          Length = 644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LKKAMTNL 9
           +KKA++NL
Sbjct: 630 MKKAISNL 637
>NP_000076
          Length = 687

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LKKAMTNL 9
           +KKA++NL
Sbjct: 673 MKKAISNL 680
>NP_001159417
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LKKAMTNL 9
           +KKA++NL
Sbjct: 503 MKKAISNL 510
>NP_001008781
          Length = 4557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LKKAMTN 8
           LKK++TN
Sbjct: 635 LKKSLTN 641
>NP_001254
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VLKKAMTNL 9
          +LKKA++ L
Sbjct: 71 ILKKALSGL 79
>NP_004061
          Length = 687

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LKKAMTNL 9
           +KKA++NL
Sbjct: 673 MKKAISNL 680
>XP_005262744
          Length = 421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VLKKAMTNL 9
          +LKKA++ L
Sbjct: 71 ILKKALSGL 79
>XP_005245790
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LKKAMTNL 9
           +KKA++NL
Sbjct: 672 MKKAISNL 679
>XP_006710132
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LKKAMTNL 9
           +KKA++NL
Sbjct: 504 MKKAISNL 511
>NP_001036169
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LKKAMTNL 9
           +KKA++NL
Sbjct: 672 MKKAISNL 679
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.125    0.303 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 305,475
Number of extensions: 343
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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