Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     509
XP_005262424                                                           20     509
NP_008986                                                              17    3301
NP_849157                                                              17    3301
NP_036292                                                              17    3301
NP_001265645                                                           17    3301
XP_006717660                                                           17    3301
XP_005266987                                                           17    3301
XP_006715521                                                           17    3301
XP_006714159                                                           17    3301
XP_006714158                                                           17    3301
XP_006714157                                                           17    3301
NP_001185885                                                           17    4312
NP_001185886                                                           17    4312
NP_060912                                                              17    4312
NP_001017977                                                           17    4312
XP_005245390                                                           17    4312
XP_005245389                                                           17    4312
XP_005245388                                                           17    4312
NP_005752                                                              16    7355
XP_006719249                                                           16    7355
XP_006717649                                                           16    7355
XP_006717648                                                           16    7355
XP_006717645                                                           16    7355
XP_006717642                                                           16    7355
XP_006717640                                                           16    7355
XP_006717639                                                           16    7355
XP_006717638                                                           16    7355
XP_006717637                                                           16    7355
XP_006717636                                                           16    7355
XP_006717635                                                           16    7355
XP_006717634                                                           16    7355
XP_006717633                                                           16    7355
XP_006717632                                                           16    7355
XP_006717631                                                           16    7355
XP_005269471                                                           16    7355
XP_006717630                                                           16    7355
XP_006717629                                                           16    7355
XP_005269469                                                           16    7355
XP_005269468                                                           16    7355
XP_006717628                                                           16    7355
XP_006717627                                                           16    7355
XP_006717626                                                           16    7355
XP_006717625                                                           16    7355
XP_006717624                                                           16    7355
XP_005269463                                                           16    7355
XP_005269461                                                           16    7355
XP_006717623                                                           16    7355
XP_005269462                                                           16    7355
NP_004332                                                              15    9605
NP_775862                                                              15    9605
XP_005268859                                                           15    9605
XP_005264615                                                           15    9605
XP_006712164                                                           15    9605
XP_005264614                                                           15    9605
XP_005264613                                                           15    9605
XP_005264612                                                           15    9605
>NP_722576
          Length = 3080

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VLGTRMTSN 9
            VLGTRMTS+
Sbjct: 1865 VLGTRMTSS 1873
>XP_005262424
          Length = 2875

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VLGTRMTSN 9
            VLGTRMTS+
Sbjct: 1660 VLGTRMTSS 1668
>NP_008986
          Length = 1390

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    VLGTRMTSN 9
            V GTR TSN
Sbjct: 1241 VKGTRTTSN 1249
>NP_849157
          Length = 1077

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           ++GT MTSN
Sbjct: 497 LVGTMMTSN 505
>NP_036292
          Length = 621

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VLGTRMTS 8
           +LGTRM S
Sbjct: 566 ILGTRMVS 573
>NP_001265645
          Length = 621

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VLGTRMTS 8
           +LGTRM S
Sbjct: 566 ILGTRMVS 573
>XP_006717660
          Length = 1369

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    VLGTRMTSN 9
            V GTR TSN
Sbjct: 1220 VKGTRTTSN 1228
>XP_005266987
          Length = 597

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VLGTRMTS 8
           +LGTRM S
Sbjct: 542 ILGTRMVS 549
>XP_006715521
          Length = 621

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VLGTRMTS 8
           +LGTRM S
Sbjct: 566 ILGTRMVS 573
>XP_006714159
          Length = 1077

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           ++GT MTSN
Sbjct: 497 LVGTMMTSN 505
>XP_006714158
          Length = 1077

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           ++GT MTSN
Sbjct: 497 LVGTMMTSN 505
>XP_006714157
          Length = 1077

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           ++GT MTSN
Sbjct: 497 LVGTMMTSN 505
>NP_001185885
          Length = 951

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VLGTRMTSN 9
           +LGTR T N
Sbjct: 223 MLGTRATGN 231
>NP_001185886
          Length = 920

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VLGTRMTSN 9
           +LGTR T N
Sbjct: 192 MLGTRATGN 200
>NP_060912
          Length = 880

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VLGTRMTSN 9
           +LGTR T N
Sbjct: 223 MLGTRATGN 231
>NP_001017977
          Length = 860

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VLGTRMTSN 9
           +LGTR T N
Sbjct: 223 MLGTRATGN 231
>XP_005245390
          Length = 874

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VLGTRMTSN 9
           +LGTR T N
Sbjct: 223 MLGTRATGN 231
>XP_005245389
          Length = 894

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VLGTRMTSN 9
           +LGTR T N
Sbjct: 223 MLGTRATGN 231
>XP_005245388
          Length = 937

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VLGTRMTSN 9
           +LGTR T N
Sbjct: 223 MLGTRATGN 231
>NP_005752
          Length = 1568

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VLGTRMTSN 9
           +LG  +TSN
Sbjct: 403 ILGENLTSN 411
>XP_006719249
          Length = 1555

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VLGTRMTSN 9
           +LG  +TSN
Sbjct: 403 ILGENLTSN 411
>XP_006717649
          Length = 1213

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>XP_006717648
          Length = 1217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>XP_006717645
          Length = 1273

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>XP_006717642
          Length = 1337

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>XP_006717640
          Length = 1424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 318 VLGPRVTSD 326
>XP_006717639
          Length = 1472

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>XP_006717638
          Length = 1511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>XP_006717637
          Length = 1531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>XP_006717636
          Length = 1539

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>XP_006717635
          Length = 1539

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>XP_006717634
          Length = 1549

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>XP_006717633
          Length = 1551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>XP_006717632
          Length = 1551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 315 VLGPRVTSD 323
>XP_006717631
          Length = 1554

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 318 VLGPRVTSD 326
>XP_005269471
          Length = 1554

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 318 VLGPRVTSD 326
>XP_006717630
          Length = 1561

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>XP_006717629
          Length = 1563

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 327 VLGPRVTSD 335
>XP_005269469
          Length = 1563

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 327 VLGPRVTSD 335
>XP_005269468
          Length = 1563

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 327 VLGPRVTSD 335
>XP_006717628
          Length = 1570

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>XP_006717627
          Length = 1573

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>XP_006717626
          Length = 1574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>XP_006717625
          Length = 1575

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>XP_006717624
          Length = 1585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>XP_005269463
          Length = 1586

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 350 VLGPRVTSD 358
>XP_005269461
          Length = 1595

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>XP_006717623
          Length = 1595

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>XP_005269462
          Length = 1595

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLGTRMTSN 9
           VLG R+TS+
Sbjct: 359 VLGPRVTSD 367
>NP_004332
          Length = 2225

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    VLGTRMTS 8
            VLG  MTS
Sbjct: 1277 VLGVEMTS 1284
>NP_775862
          Length = 2344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    VLGTRMTS 8
            VLG  MTS
Sbjct: 1220 VLGANMTS 1227
>XP_005268859
          Length = 2361

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    VLGTRMTS 8
            VLG  MTS
Sbjct: 1237 VLGANMTS 1244
>XP_005264615
          Length = 2162

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    VLGTRMTS 8
            VLG  MTS
Sbjct: 1214 VLGVEMTS 1221
>XP_006712164
          Length = 2179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    VLGTRMTS 8
            VLG  MTS
Sbjct: 1214 VLGVEMTS 1221
>XP_005264614
          Length = 2191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    VLGTRMTS 8
            VLG  MTS
Sbjct: 1277 VLGVEMTS 1284
>XP_005264613
          Length = 2208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    VLGTRMTS 8
            VLG  MTS
Sbjct: 1277 VLGVEMTS 1284
>XP_005264612
          Length = 2242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    VLGTRMTS 8
            VLG  MTS
Sbjct: 1277 VLGVEMTS 1284
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.123    0.321 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 396,709
Number of extensions: 712
Number of successful extensions: 57
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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