Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           18    1482
NP_000242                                                              18    1482
XP_005264389                                                           18    1482
NP_037510                                                              17    3301
NP_848509                                                              17    4312
XP_006710459                                                           17    4312
XP_005245803                                                           17    4312
XP_005245802                                                           17    4312
NP_075380                                                              16    7355
XP_006710602                                                           15    9605
XP_006710601                                                           15    9605
XP_006710598                                                           15    9605
XP_006710597                                                           15    9605
XP_006710596                                                           15    9605
XP_006710595                                                           15    9605
XP_006710594                                                           15    9605
XP_006710593                                                           15    9605
XP_006710592                                                           15    9605
XP_006710591                                                           15    9605
XP_006710590                                                           15    9605
XP_006710589                                                           15    9605
XP_006710588                                                           15    9605
XP_006710586                                                           15    9605
XP_006710585                                                           15    9605
XP_005270755                                                           15    9605
XP_006710584                                                           15    9605
XP_005270754                                                           15    9605
XP_005270753                                                           15    9605
XP_006710583                                                           15    9605
XP_005270752                                                           15    9605
XP_006710582                                                           15    9605
XP_005270751                                                           15    9605
>NP_001245210
          Length = 868

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   VLAQLDAV 8
           VLAQLDAV
Sbjct: 532 VLAQLDAV 539
>NP_000242
          Length = 934

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   VLAQLDAV 8
           VLAQLDAV
Sbjct: 598 VLAQLDAV 605
>XP_005264389
          Length = 921

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   VLAQLDAV 8
           VLAQLDAV
Sbjct: 598 VLAQLDAV 605
>NP_037510
          Length = 123

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  VLAQLDAV 8
          VLAQLDA+
Sbjct: 21 VLAQLDAL 28
>NP_848509
          Length = 346

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LAQLDAVA 9
           LAQL+AVA
Sbjct: 287 LAQLEAVA 294
>XP_006710459
          Length = 346

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LAQLDAVA 9
           LAQL+AVA
Sbjct: 287 LAQLEAVA 294
>XP_005245803
          Length = 346

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LAQLDAVA 9
           LAQL+AVA
Sbjct: 287 LAQLEAVA 294
>XP_005245802
          Length = 346

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LAQLDAVA 9
           LAQL+AVA
Sbjct: 287 LAQLEAVA 294
>NP_075380
          Length = 473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VLAQLDAVA 9
           VLA++DA A
Sbjct: 92  VLARIDAAA 100
>XP_006710602
          Length = 7391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3543 AQLDALA 3549
>XP_006710601
          Length = 4720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_006710598
          Length = 7553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3533 AQLDALA 3539
>XP_006710597
          Length = 7451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3543 AQLDALA 3549
>XP_006710596
          Length = 7512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3492 AQLDALA 3498
>XP_006710595
          Length = 7526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3506 AQLDALA 3512
>XP_006710594
          Length = 7528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3508 AQLDALA 3514
>XP_006710593
          Length = 7539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3519 AQLDALA 3525
>XP_006710592
          Length = 7544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3524 AQLDALA 3530
>XP_006710591
          Length = 7558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3538 AQLDALA 3544
>XP_006710590
          Length = 7563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3543 AQLDALA 3549
>XP_006710589
          Length = 7595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3575 AQLDALA 3581
>XP_006710588
          Length = 7614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_006710586
          Length = 7645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_006710585
          Length = 7657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_005270755
          Length = 7663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_006710584
          Length = 7686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_005270754
          Length = 7694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_005270753
          Length = 7700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_006710583
          Length = 7702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_005270752
          Length = 7717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_006710582
          Length = 7720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_005270751
          Length = 7723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQLDAVA 9
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.131    0.310 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 279,422
Number of extensions: 240
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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