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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              18    1135
NP_001263689                                                           18    1135
NP_001119584                                                           18    1135
NP_001119586                                                           18    1135
NP_001263625                                                           18    1135
NP_001119590                                                           18    1135
NP_001263690                                                           18    1135
NP_001119585                                                           18    1135
NP_001263624                                                           18    1135
NP_001119588                                                           18    1135
NP_001119587                                                           18    1135
NP_001119589                                                           18    1135
NP_001186074                                                           17    4312
NP_001186072                                                           17    4312
NP_001073278                                                           17    4312
NP_001263627                                                           16    5631
NP_001263628                                                           16    5631
NP_001263626                                                           16    5631
NP_001166923                                                           16    5631
NP_001166924                                                           16    5631
NP_005644                                                              16    5631
NP_001121632                                                           16    5631
NP_055368                                                              16    5631
NP_055332                                                              16    5631
XP_006712522                                                           16    5631
XP_005263709                                                           16    5631
XP_005263708                                                           16    5631
NP_001121633                                                           16    5631
NP_085915                                                              16    7355
NP_001155220                                                           16    7355
NP_064629                                                              15    9605

>NP_000537
          Length = 393

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLAMAIYKQ 9
           V AMAIYKQ
Sbjct: 157 VRAMAIYKQ 165



>NP_001263689
          Length = 354

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLAMAIYKQ 9
           V AMAIYKQ
Sbjct: 118 VRAMAIYKQ 126



>NP_001119584
          Length = 393

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLAMAIYKQ 9
           V AMAIYKQ
Sbjct: 157 VRAMAIYKQ 165



>NP_001119586
          Length = 341

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLAMAIYKQ 9
           V AMAIYKQ
Sbjct: 157 VRAMAIYKQ 165



>NP_001263625
          Length = 302

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLAMAIYKQ 9
           V AMAIYKQ
Sbjct: 118 VRAMAIYKQ 126



>NP_001119590
          Length = 354

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLAMAIYKQ 9
           V AMAIYKQ
Sbjct: 118 VRAMAIYKQ 126



>NP_001263690
          Length = 354

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLAMAIYKQ 9
           V AMAIYKQ
Sbjct: 118 VRAMAIYKQ 126



>NP_001119585
          Length = 346

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLAMAIYKQ 9
           V AMAIYKQ
Sbjct: 157 VRAMAIYKQ 165



>NP_001263624
          Length = 307

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VLAMAIYKQ 9
           V AMAIYKQ
Sbjct: 118 VRAMAIYKQ 126



>NP_001119588
          Length = 209

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VLAMAIYKQ 9
          V AMAIYKQ
Sbjct: 25 VRAMAIYKQ 33



>NP_001119587
          Length = 261

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VLAMAIYKQ 9
          V AMAIYKQ
Sbjct: 25 VRAMAIYKQ 33



>NP_001119589
          Length = 214

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VLAMAIYKQ 9
          V AMAIYKQ
Sbjct: 25 VRAMAIYKQ 33



>NP_001186074
          Length = 716

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VLAMAIYKQ 9
           VLAMA+ KQ
Sbjct: 553 VLAMALKKQ 561



>NP_001186072
          Length = 971

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VLAMAIYKQ 9
           VLAMA+ KQ
Sbjct: 808 VLAMALKKQ 816



>NP_001073278
          Length = 938

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VLAMAIYKQ 9
           VLAMA+ KQ
Sbjct: 775 VLAMALKKQ 783



>NP_001263627
          Length = 182

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4 MAIYKQ 9
         MAIYKQ
Sbjct: 1 MAIYKQ 6



>NP_001263628
          Length = 187

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4 MAIYKQ 9
         MAIYKQ
Sbjct: 1 MAIYKQ 6



>NP_001263626
          Length = 234

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4 MAIYKQ 9
         MAIYKQ
Sbjct: 1 MAIYKQ 6



>NP_001166923
          Length = 501

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VLAMAIYKQ 9
          VLA+ I+KQ
Sbjct: 43 VLALPIFKQ 51



>NP_001166924
          Length = 450

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VLAMAIYKQ 9
          VLA+ I+KQ
Sbjct: 43 VLALPIFKQ 51



>NP_005644
          Length = 502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VLAMAIYKQ 9
          VLA+ I+KQ
Sbjct: 43 VLALPIFKQ 51



>NP_001121632
          Length = 504

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VLAMAIYKQ 9
          VLA+ I+KQ
Sbjct: 40 VLALPIFKQ 48



>NP_055368
          Length = 479

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VLAMAIYKQ 9
          VLA+ I+KQ
Sbjct: 23 VLALPIFKQ 31



>NP_055332
          Length = 540

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VLAMAIYKQ 9
          VLA+ I+KQ
Sbjct: 40 VLALPIFKQ 48



>XP_006712522
          Length = 273

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VLAMAIYKQ 9
          VLA+ I+KQ
Sbjct: 23 VLALPIFKQ 31



>XP_005263709
          Length = 273

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VLAMAIYKQ 9
          VLA+ I+KQ
Sbjct: 23 VLALPIFKQ 31



>XP_005263708
          Length = 406

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VLAMAIYKQ 9
          VLA+ I+KQ
Sbjct: 23 VLALPIFKQ 31



>NP_001121633
          Length = 540

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VLAMAIYKQ 9
          VLA+ I+KQ
Sbjct: 40 VLALPIFKQ 48



>NP_085915
          Length = 215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VLAMAIY 7
           VLA+AIY
Sbjct: 155 VLALAIY 161



>NP_001155220
          Length = 173

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VLAMAIY 7
           VLA+AIY
Sbjct: 113 VLALAIY 119



>NP_064629
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VLAMAIYKQ 9
           +LA+ IYK+
Sbjct: 276 ILAIMIYKK 284



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.335    0.136    0.344 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 284,088
Number of extensions: 250
Number of successful extensions: 31
Number of sequences better than 10000.0: 31
Number of HSP's gapped: 31
Number of HSP's successfully gapped: 31
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)