Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000207                                                              18    1935
XP_005274558                                                           18    1935
NP_001245210                                                           17    3301
NP_000242                                                              17    3301
NP_001136272                                                           17    3301
XP_005264389                                                           17    3301
NP_003963                                                              17    4312
XP_005270323                                                           17    4312
XP_005270322                                                           17    4312
NP_443075                                                              16    5631
NP_001258152                                                           16    5631
NP_001092093                                                           16    5631
XP_006711892                                                           16    5631
XP_006711891                                                           16    5631
XP_006711890                                                           16    5631
XP_006711889                                                           16    5631
XP_005273367                                                           16    5631
XP_005273366                                                           16    5631
XP_006711888                                                           16    5631
XP_006711887                                                           16    5631
XP_005273364                                                           16    5631
XP_005273362                                                           16    5631
XP_005273361                                                           16    5631
XP_006711886                                                           16    5631
XP_006711885                                                           16    5631
XP_005273359                                                           16    5631
XP_006711884                                                           16    5631
XP_005273357                                                           16    5631
XP_005273356                                                           16    5631
XP_005273358                                                           16    5631
XP_005273355                                                           16    5631
XP_005273353                                                           16    5631
XP_005273352                                                           16    5631
XP_005273354                                                           16    5631
XP_005273349                                                           16    5631
XP_006711883                                                           16    5631
XP_005273350                                                           16    5631
XP_005273351                                                           16    5631
XP_006711882                                                           16    5631
XP_005273348                                                           16    5631
XP_005273346                                                           16    5631
XP_005273347                                                           16    5631
XP_005273345                                                           16    5631
XP_005273344                                                           16    5631
NP_150286                                                              16    7355
XP_005252502                                                           16    7355
NP_004499                                                              16    7355
NP_057460                                                              15    9605
NP_005056                                                              15    9605
NP_443104                                                              15    9605
NP_001244928                                                           15    9605
NP_055573                                                              15    9605
NP_057652                                                              15    9605
NP_001271203                                                           15    9605
NP_115971                                                              15    9605
NP_877497                                                              15    9605
XP_006721607                                                           15    9605
XP_005256736                                                           15    9605
XP_005268046                                                           15    9605
XP_005268045                                                           15    9605
XP_005271606                                                           15    9605
XP_005271605                                                           15    9605
XP_005269612                                                           15    9605
>NP_000207
          Length = 680

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VKYLLLVRQ 9
           +KY+LLV+Q
Sbjct: 123 LKYILLVKQ 131
>XP_005274558
          Length = 420

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VKYLLLVRQ 9
           +KY+LLV+Q
Sbjct: 123 LKYILLVKQ 131
>NP_001245210
          Length = 868

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VKYLLLVRQ 9
          VK LLLVRQ
Sbjct: 23 VKDLLLVRQ 31
>NP_000242
          Length = 934

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VKYLLLVRQ 9
          VK LLLVRQ
Sbjct: 89 VKDLLLVRQ 97
>NP_001136272
          Length = 3144

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KYLLLVRQ 9
            KY LL+RQ
Sbjct: 1970 KYTLLIRQ 1977
>XP_005264389
          Length = 921

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VKYLLLVRQ 9
          VK LLLVRQ
Sbjct: 89 VKDLLLVRQ 97
>NP_003963
          Length = 1849

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VKYLLLVRQ 9
           +KY L VRQ
Sbjct: 413 IKYALAVRQ 421
>XP_005270323
          Length = 1519

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  VKYLLLVRQ 9
          +KY L VRQ
Sbjct: 83 IKYALAVRQ 91
>XP_005270322
          Length = 1646

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VKYLLLVRQ 9
           +KY L VRQ
Sbjct: 210 IKYALAVRQ 218
>NP_443075
          Length = 6620

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 2791 KYILVVRE 2798
>NP_001258152
          Length = 8923

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3220 KYILVVRE 3227
>NP_001092093
          Length = 7968

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 2791 KYILVVRE 2798
>XP_006711892
          Length = 6865

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3036 KYILVVRE 3043
>XP_006711891
          Length = 8925

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3220 KYILVVRE 3227
>XP_006711890
          Length = 6957

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_006711889
          Length = 7297

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_005273367
          Length = 7677

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_005273366
          Length = 7678

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_006711888
          Length = 8059

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_006711887
          Length = 8499

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_005273364
          Length = 8653

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_005273362
          Length = 8675

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_005273361
          Length = 8763

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_006711886
          Length = 8833

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_006711885
          Length = 8835

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_005273359
          Length = 8843

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 2944 KYILVVRE 2951
>XP_006711884
          Length = 8847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_005273357
          Length = 8851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_005273356
          Length = 8851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_005273358
          Length = 8851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_005273355
          Length = 8924

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_005273353
          Length = 8935

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3036 KYILVVRE 3043
>XP_005273352
          Length = 8935

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3036 KYILVVRE 3043
>XP_005273354
          Length = 8935

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3036 KYILVVRE 3043
>XP_005273349
          Length = 8939

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_006711883
          Length = 8939

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_005273350
          Length = 8939

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_005273351
          Length = 8939

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_006711882
          Length = 8977

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3078 KYILVVRE 3085
>XP_005273348
          Length = 9015

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_005273346
          Length = 9026

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_005273347
          Length = 9026

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_005273345
          Length = 9026

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>XP_005273344
          Length = 9027

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KYLLLVRQ 9
            KY+L+VR+
Sbjct: 3128 KYILVVRE 3135
>NP_150286
          Length = 227

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   YLLLVRQ 9
           YLLLVR+
Sbjct: 151 YLLLVRK 157
>XP_005252502
          Length = 228

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VKYLLLVRQ 9
           + Y+LLVR+
Sbjct: 150 IDYILLVRK 158
>NP_004499
          Length = 284

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VKYLLLVRQ 9
           + Y+LLVR+
Sbjct: 206 IDYILLVRK 214
>NP_057460
          Length = 1170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  KYLLLVRQ 9
          K+L+L+RQ
Sbjct: 11 KHLMLLRQ 18
>NP_005056
          Length = 794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VKYLLLVRQ 9
           ++YLLL  Q
Sbjct: 576 IQYLLLAEQ 584
>NP_443104
          Length = 163

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  VKYLLL 6
          VKYLLL
Sbjct: 12 VKYLLL 17
>NP_001244928
          Length = 1211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  KYLLLVRQ 9
          K+L+L+RQ
Sbjct: 53 KHLMLLRQ 60
>NP_055573
          Length = 992

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   VKYLLLVRQ 9
           V+YLLL+++
Sbjct: 874 VQYLLLLQE 882
>NP_057652
          Length = 469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   YLLLVR 8
           YLLLVR
Sbjct: 287 YLLLVR 292
>NP_001271203
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   YLLLVRQ 9
           +LLL+RQ
Sbjct: 469 FLLLIRQ 475
>NP_115971
          Length = 1604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KYLLLVRQ 9
           +YLL +RQ
Sbjct: 600 RYLLFLRQ 607
>NP_877497
          Length = 776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   YLLLVRQ 9
           +LLL+RQ
Sbjct: 465 FLLLIRQ 471
>XP_006721607
          Length = 1130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  KYLLLVRQ 9
          K+L+L+RQ
Sbjct: 11 KHLMLLRQ 18
>XP_005256736
          Length = 1169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  KYLLLVRQ 9
          K+L+L+RQ
Sbjct: 11 KHLMLLRQ 18
>XP_005268046
          Length = 771

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VKYLLLVRQ 9
           ++YLLL  Q
Sbjct: 553 IQYLLLAEQ 561
>XP_005268045
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VKYLLLVRQ 9
           ++YLLL  Q
Sbjct: 555 IQYLLLAEQ 563
>XP_005271606
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   VKYLLLVRQ 9
           V+YLLL+++
Sbjct: 254 VQYLLLLQE 262
>XP_005271605
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   VKYLLLVRQ 9
           V+YLLL+++
Sbjct: 299 VQYLLLLQE 307
>XP_005269612
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   YLLLVRQ 9
           +LLL+RQ
Sbjct: 358 FLLLIRQ 364
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.341    0.155    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 404,085
Number of extensions: 594
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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