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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           17    3301
NP_000242                                                              17    3301
NP_060786                                                              17    3301
XP_006722848                                                           17    3301
XP_005264389                                                           17    3301
NP_001277675                                                           17    4312
NP_001180575                                                           17    4312
NP_036200                                                              17    4312
NP_689807                                                              16    5631
NP_059119                                                              16    5631
NP_112598                                                              16    5631
XP_005254260                                                           16    5631
XP_005254259                                                           16    5631
XP_005267824                                                           16    5631
XP_005263119                                                           16    5631
NP_059133                                                              16    5631
NP_878274                                                              16    7355
NP_976046                                                              15    9605
NP_038478                                                              15    9605
NP_001276904                                                           15    9605
NP_000772                                                              15    9605
NP_001093243                                                           15    9605
NP_038477                                                              15    9605
XP_006720468                                                           15    9605
XP_006720467                                                           15    9605
XP_006719271                                                           15    9605
XP_005268661                                                           15    9605
XP_005268660                                                           15    9605
XP_005268659                                                           15    9605
XP_005268657                                                           15    9605
XP_006719270                                                           15    9605
XP_005268656                                                           15    9605
XP_005268654                                                           15    9605
XP_005268653                                                           15    9605
XP_006712537                                                           15    9605
XP_006712536                                                           15    9605
XP_005246557                                                           15    9605
XP_006712535                                                           15    9605
XP_006712534                                                           15    9605
XP_006712533                                                           15    9605
XP_006712532                                                           15    9605
XP_006712531                                                           15    9605
XP_006712530                                                           15    9605
XP_006712529                                                           15    9605
XP_006712528                                                           15    9605
XP_006712527                                                           15    9605
XP_005246549                                                           15    9605
XP_006712526                                                           15    9605
XP_006712525                                                           15    9605
XP_005246546                                                           15    9605
XP_006712524                                                           15    9605
XP_005246545                                                           15    9605

>NP_001245210
          Length = 868

 Score = 16.9 bits (32), Expect =  3301
 Identities = 9/10 (90%), Positives = 9/10 (90%), Gaps = 1/10 (10%)

Query: 1  VKDLL-VRQY 9
          VKDLL VRQY
Sbjct: 23 VKDLLLVRQY 32



>NP_000242
          Length = 934

 Score = 16.9 bits (32), Expect =  3301
 Identities = 9/10 (90%), Positives = 9/10 (90%), Gaps = 1/10 (10%)

Query: 1  VKDLL-VRQY 9
          VKDLL VRQY
Sbjct: 89 VKDLLLVRQY 98



>NP_060786
          Length = 615

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VKDLLVRQY 9
           V+D+L RQY
Sbjct: 272 VEDVLCRQY 280



>XP_006722848
          Length = 604

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VKDLLVRQY 9
           V+D+L RQY
Sbjct: 261 VEDVLCRQY 269



>XP_005264389
          Length = 921

 Score = 16.9 bits (32), Expect =  3301
 Identities = 9/10 (90%), Positives = 9/10 (90%), Gaps = 1/10 (10%)

Query: 1  VKDLL-VRQY 9
          VKDLL VRQY
Sbjct: 89 VKDLLLVRQY 98



>NP_001277675
          Length = 282

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VKDLLVRQY 9
           VKDLL+  Y
Sbjct: 264 VKDLLIEVY 272



>NP_001180575
          Length = 282

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VKDLLVRQY 9
           VKDLL+  Y
Sbjct: 264 VKDLLIEVY 272



>NP_036200
          Length = 282

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VKDLLVRQY 9
           VKDLL+  Y
Sbjct: 264 VKDLLIEVY 272



>NP_689807
          Length = 444

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   KDLLVRQY 9
           +D+L+R+Y
Sbjct: 251 RDILIRRY 258



>NP_059119
          Length = 657

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KDLLVRQY 9
           KD++ RQY
Sbjct: 105 KDIMQRQY 112



>NP_112598
          Length = 5088

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KDLLVRQY 9
            KDL+VR++
Sbjct: 1669 KDLIVREH 1676




 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KDLLVRQY 9
            KDL+VR++
Sbjct: 2327 KDLIVREH 2334




 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KDLLVRQY 9
            KDL+VR++
Sbjct: 2863 KDLIVREH 2870




 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KDLLVRQY 9
            KDL+VR++
Sbjct: 3394 KDLIVREH 3401




 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KDLLVRQY 9
            KDL+VR++
Sbjct: 3928 KDLIVREH 3935




 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KDLLVRQY 9
            KDL+VR++
Sbjct: 4462 KDLIVREH 4469




 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    KDLLVRQY 9
            KDL+VR++
Sbjct: 4995 KDLIVREH 5002



>XP_005254260
          Length = 370

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   KDLLVRQY 9
           +D+L+R+Y
Sbjct: 177 RDILIRRY 184



>XP_005254259
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   KDLLVRQY 9
           +D+L+R+Y
Sbjct: 263 RDILIRRY 270



>XP_005267824
          Length = 782

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VKDLLVRQY 9
           ++DLL  QY
Sbjct: 771 IRDLLYEQY 779



>XP_005263119
          Length = 657

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KDLLVRQY 9
           KD++ RQY
Sbjct: 105 KDIMQRQY 112



>NP_059133
          Length = 782

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VKDLLVRQY 9
           ++DLL  QY
Sbjct: 771 IRDLLYEQY 779



>NP_878274
          Length = 316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VKDLLVRQY 9
           +K+L VR+Y
Sbjct: 306 LKELTVREY 314



>NP_976046
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VKDLLVRQY 9
           + DL+ RQY
Sbjct: 410 IVDLISRQY 418



>NP_038478
          Length = 2168

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1135 VQDLLVR 1141



>NP_001276904
          Length = 2132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1099 VQDLLVR 1105



>NP_000772
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VKDLLVRQY 9
           V DL++R Y
Sbjct: 399 VNDLVLRDY 407



>NP_001093243
          Length = 363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VKDLLVRQY 9
           V DL++R Y
Sbjct: 241 VNDLVLRDY 249



>NP_038477
          Length = 1905

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VKDLLVR 7
           V+DLLVR
Sbjct: 896 VQDLLVR 902



>XP_006720468
          Length = 433

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VKDLLVRQY 9
           V DL++R Y
Sbjct: 311 VNDLVLRDY 319



>XP_006720467
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VKDLLVRQY 9
           V DL++R Y
Sbjct: 328 VNDLVLRDY 336



>XP_006719271
          Length = 1555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VKDLLVR 7
           V+DLLVR
Sbjct: 915 VQDLLVR 921



>XP_005268661
          Length = 1657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VKDLLVR 7
           V+DLLVR
Sbjct: 648 VQDLLVR 654



>XP_005268660
          Length = 1875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VKDLLVR 7
           V+DLLVR
Sbjct: 866 VQDLLVR 872



>XP_005268659
          Length = 1894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VKDLLVR 7
           V+DLLVR
Sbjct: 885 VQDLLVR 891



>XP_005268657
          Length = 1903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VKDLLVR 7
           V+DLLVR
Sbjct: 894 VQDLLVR 900



>XP_006719270
          Length = 1903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VKDLLVR 7
           V+DLLVR
Sbjct: 894 VQDLLVR 900



>XP_005268656
          Length = 1903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VKDLLVR 7
           V+DLLVR
Sbjct: 894 VQDLLVR 900



>XP_005268654
          Length = 1923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VKDLLVR 7
           V+DLLVR
Sbjct: 915 VQDLLVR 921



>XP_005268653
          Length = 1924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VKDLLVR 7
           V+DLLVR
Sbjct: 915 VQDLLVR 921



>XP_006712537
          Length = 1952

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1146 VQDLLVR 1152



>XP_006712536
          Length = 2082

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1014 VQDLLVR 1020



>XP_005246557
          Length = 2095

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1027 VQDLLVR 1033



>XP_006712535
          Length = 2095

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1027 VQDLLVR 1033



>XP_006712534
          Length = 2114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1046 VQDLLVR 1052



>XP_006712533
          Length = 2116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1048 VQDLLVR 1054



>XP_006712532
          Length = 2141

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1108 VQDLLVR 1114



>XP_006712531
          Length = 2169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1101 VQDLLVR 1107



>XP_006712530
          Length = 2176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1108 VQDLLVR 1114



>XP_006712529
          Length = 2179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1146 VQDLLVR 1152



>XP_006712528
          Length = 2180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1112 VQDLLVR 1118



>XP_006712527
          Length = 2203

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1135 VQDLLVR 1141



>XP_005246549
          Length = 2212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1144 VQDLLVR 1150



>XP_006712526
          Length = 2212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1144 VQDLLVR 1150



>XP_006712525
          Length = 2212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1144 VQDLLVR 1150



>XP_005246546
          Length = 2214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1146 VQDLLVR 1152



>XP_006712524
          Length = 2214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1146 VQDLLVR 1152



>XP_005246545
          Length = 2214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VKDLLVR 7
            V+DLLVR
Sbjct: 1146 VQDLLVR 1152



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.149    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 500,287
Number of extensions: 882
Number of successful extensions: 58
Number of sequences better than 10000.0: 52
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)