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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001261                                                              20     299
NP_001262                                                              20     299
XP_005271924                                                           20     299
XP_005271923                                                           20     299
NP_001275743                                                           17    2528
NP_115826                                                              17    2528
XP_006716698                                                           17    2528
XP_006716697                                                           17    2528
XP_006716696                                                           17    2528
XP_006716695                                                           17    2528
XP_006716694                                                           17    2528
XP_006716693                                                           17    2528
XP_006716692                                                           17    2528
XP_006716691                                                           17    2528
XP_006716690                                                           17    2528
XP_006716689                                                           17    2528
NP_001107                                                              16    5631
XP_006724224                                                           16    5631
XP_005255136                                                           16    5631
NP_872333                                                              16    5631
NP_000543                                                              16    7355
NP_001124162                                                           16    7355
XP_006715451                                                           16    7355
XP_006715384                                                           16    7355
NP_612377                                                              15    9605
NP_001254656                                                           15    9605
NP_055775                                                              15    9605
XP_006721842                                                           15    9605
XP_005257229                                                           15    9605
XP_006721840                                                           15    9605
XP_005257227                                                           15    9605
XP_006721839                                                           15    9605

>NP_001261
          Length = 1710

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VIQRMDTSG 9
           VIQRMDT+G
Sbjct: 936 VIQRMDTTG 944



>NP_001262
          Length = 1828

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VIQRMDTSG 9
           VIQRMDT+G
Sbjct: 939 VIQRMDTTG 947



>XP_005271924
          Length = 1710

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VIQRMDTSG 9
           VIQRMDT+G
Sbjct: 936 VIQRMDTTG 944



>XP_005271923
          Length = 1798

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VIQRMDTSG 9
           VIQRMDT+G
Sbjct: 936 VIQRMDTTG 944



>NP_001275743
          Length = 1632

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VIQRMDTSG 9
            V+QRMD  G
Sbjct: 1273 VVQRMDLEG 1281



>NP_115826
          Length = 1641

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VIQRMDTSG 9
            V+QRMD  G
Sbjct: 1282 VVQRMDLEG 1290



>XP_006716698
          Length = 1481

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VIQRMDTSG 9
            V+QRMD  G
Sbjct: 1282 VVQRMDLEG 1290



>XP_006716697
          Length = 1578

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VIQRMDTSG 9
            V+QRMD  G
Sbjct: 1282 VVQRMDLEG 1290



>XP_006716696
          Length = 1585

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VIQRMDTSG 9
            V+QRMD  G
Sbjct: 1214 VVQRMDLEG 1222



>XP_006716695
          Length = 1585

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VIQRMDTSG 9
            V+QRMD  G
Sbjct: 1214 VVQRMDLEG 1222



>XP_006716694
          Length = 1632

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VIQRMDTSG 9
            V+QRMD  G
Sbjct: 1273 VVQRMDLEG 1281



>XP_006716693
          Length = 1644

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VIQRMDTSG 9
            V+QRMD  G
Sbjct: 1273 VVQRMDLEG 1281



>XP_006716692
          Length = 1644

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VIQRMDTSG 9
            V+QRMD  G
Sbjct: 1273 VVQRMDLEG 1281



>XP_006716691
          Length = 1653

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VIQRMDTSG 9
            V+QRMD  G
Sbjct: 1282 VVQRMDLEG 1290



>XP_006716690
          Length = 1653

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VIQRMDTSG 9
            V+QRMD  G
Sbjct: 1282 VVQRMDLEG 1290



>XP_006716689
          Length = 1653

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VIQRMDTSG 9
            V+QRMD  G
Sbjct: 1282 VVQRMDLEG 1290



>NP_001107
          Length = 1353

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VIQRMDTSG 9
            +  RMDT+G
Sbjct: 1193 IASRMDTTG 1201



>XP_006724224
          Length = 211

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VIQRMDTSG 9
          +IQR+D  G
Sbjct: 77 IIQRLDMDG 85



>XP_005255136
          Length = 1372

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VIQRMDTSG 9
            +  RMDT+G
Sbjct: 1212 IASRMDTTG 1220



>NP_872333
          Length = 215

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VIQRMDTSG 9
          +IQR+D  G
Sbjct: 77 IIQRLDMDG 85



>NP_000543
          Length = 2813

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    VIQRMD 6
            VIQRMD
Sbjct: 1524 VIQRMD 1529



>NP_001124162
          Length = 789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   QRMDTSG 9
           QR+DT G
Sbjct: 94  QRLDTGG 100



>XP_006715451
          Length = 1475

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IQRMDTSG 9
            I+RM TSG
Sbjct: 1168 IRRMGTSG 1175



>XP_006715384
          Length = 772

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  QRMDTSG 9
          QR+DT G
Sbjct: 77 QRLDTGG 83



>NP_612377
          Length = 878

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VIQRMDTS 8
           VIQ +DTS
Sbjct: 271 VIQLLDTS 278



>NP_001254656
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   IQRMDTSG 9
           IQR  TSG
Sbjct: 231 IQRASTSG 238



>NP_055775
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   IQRMDTSG 9
           IQR  TSG
Sbjct: 231 IQRASTSG 238



>XP_006721842
          Length = 329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   IQRMDTSG 9
           IQR  TSG
Sbjct: 231 IQRASTSG 238



>XP_005257229
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   IQRMDTSG 9
           IQR  TSG
Sbjct: 231 IQRASTSG 238



>XP_006721840
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   IQRMDTSG 9
           IQR  TSG
Sbjct: 231 IQRASTSG 238



>XP_005257227
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   IQRMDTSG 9
           IQR  TSG
Sbjct: 231 IQRASTSG 238



>XP_006721839
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   IQRMDTSG 9
           IQR  TSG
Sbjct: 231 IQRASTSG 238



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.131    0.344 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 462,185
Number of extensions: 647
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)