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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     390
XP_005262424                                                           20     390
NP_078966                                                              17    3301
NP_060887                                                              17    4312
NP_001161221                                                           17    4312
XP_005245386                                                           17    4312
XP_006711512                                                           17    4312
NP_775882                                                              16    5631
NP_003676                                                              15    9605
NP_203129                                                              15    9605
NP_079071                                                              15    9605
NP_001135799                                                           15    9605
NP_001135798                                                           15    9605
NP_066968                                                              15    9605
NP_954672                                                              15    9605
NP_835258                                                              15    9605
NP_055379                                                              15    9605
NP_057669                                                              15    9605
XP_005276538                                                           15    9605
XP_005259725                                                           15    9605
XP_005259626                                                           15    9605
XP_005255056                                                           15    9605
XP_005263467                                                           15    9605
XP_006716269                                                           15    9605
XP_006716267                                                           15    9605
XP_006716266                                                           15    9605
XP_005250791                                                           15    9605
XP_006716265                                                           15    9605
XP_006716264                                                           15    9605
XP_006716263                                                           15    9605
XP_006716262                                                           15    9605
XP_006716261                                                           15    9605
XP_006716260                                                           15    9605

>NP_722576
          Length = 3080

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VIPRTTMTM 9
            V PRTTMTM
Sbjct: 1595 VTPRTTMTM 1603



>XP_005262424
          Length = 2875

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VIPRTTMTM 9
            V PRTTMTM
Sbjct: 1390 VTPRTTMTM 1398



>NP_078966
          Length = 14507

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    IPRTTMTM 9
            +P TT+TM
Sbjct: 2681 VPETTLTM 2688



>NP_060887
          Length = 1610

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VIPRTTMTM 9
            ++PR TMT+
Sbjct: 1449 LLPRRTMTL 1457



>NP_001161221
          Length = 1457

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VIPRTTMTM 9
            ++PR TMT+
Sbjct: 1296 LLPRRTMTL 1304



>XP_005245386
          Length = 1518

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VIPRTTMTM 9
            ++PR TMT+
Sbjct: 1357 LLPRRTMTL 1365



>XP_006711512
          Length = 1547

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VIPRTTMTM 9
            ++PR TMT+
Sbjct: 1449 LLPRRTMTL 1457



>NP_775882
          Length = 433

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PRTTMTM 9
           P+TT+TM
Sbjct: 262 PKTTITM 268



>NP_003676
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   PRTTMT 8
           PRT+MT
Sbjct: 141 PRTSMT 146



>NP_203129
          Length = 390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   PRTTMT 8
           PRTT+T
Sbjct: 160 PRTTIT 165



>NP_079071
          Length = 229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  IPRTTMTM 9
          IP TTM++
Sbjct: 63 IPATTMSL 70



>NP_001135799
          Length = 760

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VIPRTTMT 8
           V+P TT+T
Sbjct: 717 VLPLTTLT 724



>NP_001135798
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VIPRTTMT 8
           V+P TT+T
Sbjct: 629 VLPLTTLT 636



>NP_066968
          Length = 760

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VIPRTTMT 8
           V+P TT+T
Sbjct: 717 VLPLTTLT 724



>NP_954672
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   IPRTTMT 8
           +P TTMT
Sbjct: 111 LPSTTMT 117



>NP_835258
          Length = 397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   PRTTMT 8
           PRTT+T
Sbjct: 160 PRTTIT 165



>NP_055379
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   PRTTMT 8
           PRTT+T
Sbjct: 165 PRTTIT 170



>NP_057669
          Length = 379

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   IPRTTMT 8
           +P TTMT
Sbjct: 111 LPSTTMT 117



>XP_005276538
          Length = 105

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  IPRTTMTM 9
          I RTT+TM
Sbjct: 41 INRTTVTM 48



>XP_005259725
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   PRTTMT 8
           PRT+MT
Sbjct: 141 PRTSMT 146



>XP_005259626
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   IPRTTMT 8
           +P TTMT
Sbjct: 147 LPSTTMT 153



>XP_005255056
          Length = 105

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  IPRTTMTM 9
          I RTT+TM
Sbjct: 41 INRTTVTM 48



>XP_005263467
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   PRTTMT 8
           PRTT+T
Sbjct: 149 PRTTIT 154



>XP_006716269
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VIPRTTMT 8
           V+P TT+T
Sbjct: 458 VLPLTTLT 465



>XP_006716267
          Length = 726

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VIPRTTMT 8
           V+P TT+T
Sbjct: 683 VLPLTTLT 690



>XP_006716266
          Length = 726

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VIPRTTMT 8
           V+P TT+T
Sbjct: 683 VLPLTTLT 690



>XP_005250791
          Length = 760

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VIPRTTMT 8
           V+P TT+T
Sbjct: 717 VLPLTTLT 724



>XP_006716265
          Length = 760

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VIPRTTMT 8
           V+P TT+T
Sbjct: 717 VLPLTTLT 724



>XP_006716264
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VIPRTTMT 8
           V+P TT+T
Sbjct: 724 VLPLTTLT 731



>XP_006716263
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VIPRTTMT 8
           V+P TT+T
Sbjct: 724 VLPLTTLT 731



>XP_006716262
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VIPRTTMT 8
           V+P TT+T
Sbjct: 724 VLPLTTLT 731



>XP_006716261
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VIPRTTMT 8
           V+P TT+T
Sbjct: 724 VLPLTTLT 731



>XP_006716260
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VIPRTTMT 8
           V+P TT+T
Sbjct: 724 VLPLTTLT 731



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.129    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 586,461
Number of extensions: 844
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)