Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              18    1135
NP_001010860                                                           17    3301
NP_000918                                                              16    5631
NP_150094                                                              16    7355
NP_001278261                                                           16    7355
NP_001034553                                                           16    7355
NP_056372                                                              16    7355
NP_775105                                                              16    7355
NP_689967                                                              16    7355
NP_001036148                                                           16    7355
XP_006715506                                                           16    7355
XP_006715505                                                           16    7355
XP_006715504                                                           16    7355
XP_006715503                                                           16    7355
XP_006715502                                                           16    7355
NP_001005165                                                           16    7355
NP_000310                                                              15    9605
NP_001124497                                                           15    9605
NP_001124495                                                           15    9605
NP_001124496                                                           15    9605
NP_001124498                                                           15    9605
NP_001243683                                                           15    9605
NP_001243681                                                           15    9605
NP_001243684                                                           15    9605
NP_001243680                                                           15    9605
NP_001243679                                                           15    9605
NP_001243682                                                           15    9605
NP_057643                                                              15    9605
NP_001243685                                                           15    9605
NP_001128643                                                           15    9605
NP_001128642                                                           15    9605
NP_659415                                                              15    9605
NP_005843                                                              15    9605
NP_114117                                                              15    9605
NP_001005273                                                           15    9605
NP_060125                                                              15    9605
XP_006725230                                                           15    9605
XP_006721493                                                           15    9605
XP_006721492                                                           15    9605
XP_006721491                                                           15    9605
XP_006721490                                                           15    9605
XP_006721489                                                           15    9605
XP_006721488                                                           15    9605
XP_005256486                                                           15    9605
XP_005256485                                                           15    9605
XP_006721487                                                           15    9605
XP_006721486                                                           15    9605
XP_005256484                                                           15    9605
XP_006720283                                                           15    9605
XP_006719195                                                           15    9605
XP_005253512                                                           15    9605
XP_006719194                                                           15    9605
XP_006719193                                                           15    9605
XP_005253510                                                           15    9605
XP_005253509                                                           15    9605
XP_006719192                                                           15    9605
XP_005253508                                                           15    9605
XP_005247583                                                           15    9605
XP_005247581                                                           15    9605
XP_006713719                                                           15    9605
XP_005263951                                                           15    9605
XP_006712408                                                           15    9605
XP_006712407                                                           15    9605
XP_005271015                                                           15    9605
XP_005271014                                                           15    9605
XP_005271013                                                           15    9605
XP_006710313                                                           15    9605
NP_001005271                                                           15    9605
NP_055839                                                              15    9605
NP_065869                                                              15    9605
>NP_115803
          Length = 1156

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VIKSEYSLG 9
           VIKSEYS G
Sbjct: 363 VIKSEYSPG 371
>NP_001010860
          Length = 674

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IKSEYSLG 9
           IKS+YS+G
Sbjct: 428 IKSKYSVG 435
>NP_000918
          Length = 1280

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VIKSEYSLG 9
           V+  EYS+G
Sbjct: 321 VLSGEYSIG 329
>NP_150094
          Length = 3564

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VIKSEYSLG 9
            +I S+YS+G
Sbjct: 2098 MINSDYSVG 2106
>NP_001278261
          Length = 841

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   IKSEYSLG 9
           I  EYSLG
Sbjct: 516 IPEEYSLG 523
>NP_001034553
          Length = 1323

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    IKSEYSLG 9
            I  EYSLG
Sbjct: 998  IPEEYSLG 1005
>NP_056372
          Length = 1954

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KSEYSLG 9
            +SEYS+G
Sbjct: 1369 QSEYSIG 1375
>NP_775105
          Length = 1659

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VIKSEYSL 8
            +IK EY+L
Sbjct: 1044 IIKGEYAL 1051
>NP_689967
          Length = 777

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VIKSEYSL 8
           +IK+EY L
Sbjct: 643 IIKTEYGL 650
>NP_001036148
          Length = 1683

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VIKSEYSL 8
            +IK EY+L
Sbjct: 1035 IIKGEYAL 1042
>XP_006715506
          Length = 1507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VIKSEYSL 8
            +IK EY+L
Sbjct: 1035 IIKGEYAL 1042
>XP_006715505
          Length = 1673

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VIKSEYSL 8
            +IK EY+L
Sbjct: 1035 IIKGEYAL 1042
>XP_006715504
          Length = 1683

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VIKSEYSL 8
            +IK EY+L
Sbjct: 1035 IIKGEYAL 1042
>XP_006715503
          Length = 1707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VIKSEYSL 8
            +IK EY+L
Sbjct: 1035 IIKGEYAL 1042
>XP_006715502
          Length = 1707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VIKSEYSL 8
            +IK EY+L
Sbjct: 1035 IIKGEYAL 1042
>NP_001005165
          Length = 312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  VIKSEYSL 8
          VIK+E+SL
Sbjct: 50 VIKTEHSL 57
>NP_000310
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 548 IRSRYNLG 555
>NP_001124497
          Length = 639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 556 IRSRYNLG 563
>NP_001124495
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 571 IRSRYNLG 578
>NP_001124496
          Length = 602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 519 IRSRYNLG 526
>NP_001124498
          Length = 639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 556 IRSRYNLG 563
>NP_001243683
          Length = 583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 499 IRSRYNLG 506
>NP_001243681
          Length = 591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 507 IRSRYNLG 514
>NP_001243684
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 434 IRSRYNLG 441
>NP_001243680
          Length = 602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 518 IRSRYNLG 525
>NP_001243679
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 540 IRSRYNLG 547
>NP_001243682
          Length = 567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 483 IRSRYNLG 490
>NP_057643
          Length = 626

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 542 IRSRYNLG 549
>NP_001243685
          Length = 434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 350 IRSRYNLG 357
>NP_001128643
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIKSEYSLG 9
           V+KS +S+G
Sbjct: 145 VLKSAFSVG 153
>NP_001128642
          Length = 296

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIKSEYSLG 9
           V+KS +S+G
Sbjct: 152 VLKSAFSVG 160
>NP_659415
          Length = 665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  IKSEYSLG 9
          +KS Y LG
Sbjct: 18 LKSRYGLG 25
>NP_005843
          Length = 1966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KSEYSLG 9
            +SEYS+G
Sbjct: 1360 QSEYSVG 1366
>NP_114117
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIKSEYSLG 9
           V+KS +S+G
Sbjct: 145 VLKSAFSVG 153
>NP_001005273
          Length = 2000

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KSEYSLG 9
            +SEYS+G
Sbjct: 1360 QSEYSVG 1366
>NP_060125
          Length = 315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VIKSEYSLG 9
           V KSE SLG
Sbjct: 120 VYKSEDSLG 128
>XP_006725230
          Length = 2636

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VIKSEYS 7
            V+KSE+S
Sbjct: 1016 VVKSEFS 1022
>XP_006721493
          Length = 2056

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KSEYSLG 9
            +SEYS+G
Sbjct: 1415 QSEYSVG 1421
>XP_006721492
          Length = 1924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KSEYSLG 9
            +SEYS+G
Sbjct: 1419 QSEYSVG 1425
>XP_006721491
          Length = 2025

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KSEYSLG 9
            +SEYS+G
Sbjct: 1419 QSEYSVG 1425
>XP_006721490
          Length = 2036

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KSEYSLG 9
            +SEYS+G
Sbjct: 1340 QSEYSVG 1346
>XP_006721489
          Length = 2045

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KSEYSLG 9
            +SEYS+G
Sbjct: 1419 QSEYSVG 1425
>XP_006721488
          Length = 2056

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KSEYSLG 9
            +SEYS+G
Sbjct: 1360 QSEYSVG 1366
>XP_005256486
          Length = 2060

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KSEYSLG 9
            +SEYS+G
Sbjct: 1419 QSEYSVG 1425
>XP_005256485
          Length = 2080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KSEYSLG 9
            +SEYS+G
Sbjct: 1419 QSEYSVG 1425
>XP_006721487
          Length = 2111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KSEYSLG 9
            +SEYS+G
Sbjct: 1415 QSEYSVG 1421
>XP_006721486
          Length = 2114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KSEYSLG 9
            +SEYS+G
Sbjct: 1419 QSEYSVG 1425
>XP_005256484
          Length = 2115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KSEYSLG 9
            +SEYS+G
Sbjct: 1419 QSEYSVG 1425
>XP_006720283
          Length = 2636

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VIKSEYS 7
            V+KSE+S
Sbjct: 1016 VVKSEFS 1022
>XP_006719195
          Length = 565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 482 IRSRYNLG 489
>XP_005253512
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 540 IRSRYNLG 547
>XP_006719194
          Length = 639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 556 IRSRYNLG 563
>XP_006719193
          Length = 648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 565 IRSRYNLG 572
>XP_005253510
          Length = 648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 565 IRSRYNLG 572
>XP_005253509
          Length = 660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 577 IRSRYNLG 584
>XP_006719192
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 586 IRSRYNLG 593
>XP_005253508
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 586 IRSRYNLG 593
>XP_005247583
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 430 IRSRYNLG 437
>XP_005247581
          Length = 650

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 566 IRSRYNLG 573
>XP_006713719
          Length = 583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           I+S Y+LG
Sbjct: 499 IRSRYNLG 506
>XP_005263951
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  IKSEYSLG 9
          +KS Y LG
Sbjct: 18 LKSRYGLG 25
>XP_006712408
          Length = 583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  IKSEYSLG 9
          +KS Y LG
Sbjct: 18 LKSRYGLG 25
>XP_006712407
          Length = 671

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  IKSEYSLG 9
          +KS Y LG
Sbjct: 18 LKSRYGLG 25
>XP_005271015
          Length = 223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  VIKSEYSLG 9
          V KSE SLG
Sbjct: 28 VYKSEDSLG 36
>XP_005271014
          Length = 241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  VIKSEYSLG 9
          V KSE SLG
Sbjct: 46 VYKSEDSLG 54
>XP_005271013
          Length = 249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VIKSEYSLG 9
           V KSE SLG
Sbjct: 120 VYKSEDSLG 128
>XP_006710313
          Length = 160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   IKSEYSLG 9
           ++ EYS+G
Sbjct: 126 VRGEYSVG 133
>NP_001005271
          Length = 2059

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KSEYSLG 9
            +SEYS+G
Sbjct: 1419 QSEYSVG 1425
>NP_055839
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   IKSEYSLG 9
           +KS Y LG
Sbjct: 337 LKSNYQLG 344
>NP_065869
          Length = 2458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VIKSEYS 7
           V+KSE+S
Sbjct: 838 VVKSEFS 844
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.132    0.332 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 529,752
Number of extensions: 753
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package