Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005224                                                              18    1935
NP_004422                                                              18    1935
NP_000258                                                              18    1935
NP_001035957                                                           18    1935
XP_006721990                                                           18    1935
XP_006721989                                                           18    1935
XP_005258041                                                           18    1935
XP_006721988                                                           18    1935
XP_006721987                                                           18    1935
XP_006721986                                                           18    1935
XP_005258040                                                           18    1935
XP_006721985                                                           18    1935
XP_005264773                                                           18    1935
XP_005264772                                                           18    1935
XP_005245809                                                           18    1935
XP_005245808                                                           18    1935
NP_001095139                                                           17    3301
NP_003857                                                              17    3301
XP_006714467                                                           17    3301
XP_005263382                                                           17    3301
XP_005263381                                                           17    3301
XP_006714466                                                           17    3301
XP_005263380                                                           17    3301
XP_006714465                                                           17    3301
XP_005263379                                                           17    3301
XP_006714464                                                           17    3301
XP_006714463                                                           17    3301
NP_001275558                                                           17    4312
NP_004431                                                              17    4312
XP_006715432                                                           17    4312
XP_005248726                                                           17    4312
NP_002882                                                              16    5631
NP_001139120                                                           16    5631
NP_036364                                                              16    5631
NP_004648                                                              16    5631
XP_005257299                                                           16    5631
XP_006720692                                                           16    5631
XP_006720691                                                           16    5631
XP_006720690                                                           16    5631
XP_005254635                                                           16    5631
NP_001074001                                                           16    7355
NP_689549                                                              15    9605
NP_001122326                                                           15    9605
NP_001122324                                                           15    9605
NP_001122325                                                           15    9605
NP_056992                                                              15    9605
NP_079421                                                              15    9605
NP_004429                                                              15    9605
NP_758963                                                              15    9605
NP_001268695                                                           15    9605
NP_872272                                                              15    9605
NP_055918                                                              15    9605
NP_004430                                                              15    9605
NP_001268694                                                           15    9605
NP_001268696                                                           15    9605
XP_005270233                                                           15    9605
XP_005270231                                                           15    9605
XP_005270230                                                           15    9605
XP_005270229                                                           15    9605
XP_005270228                                                           15    9605
XP_006716086                                                           15    9605
XP_005250465                                                           15    9605
XP_005250464                                                           15    9605
XP_005250463                                                           15    9605
XP_005250462                                                           15    9605
XP_005265710                                                           15    9605
XP_005246431                                                           15    9605
>NP_005224
          Length = 983

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VIAILDKLI 9
           +++ILDKLI
Sbjct: 874 IVSILDKLI 882
>NP_004422
          Length = 976

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VIAILDKLI 9
           +++ILDKLI
Sbjct: 867 IVSILDKLI 875
>NP_000258
          Length = 2818

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VIAILDKLI 9
            V AILDKLI
Sbjct: 1950 VTAILDKLI 1958
>NP_001035957
          Length = 2839

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VIAILDKLI 9
            V AILDKLI
Sbjct: 1971 VTAILDKLI 1979
>XP_006721990
          Length = 2823

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VIAILDKLI 9
            V AILDKLI
Sbjct: 1981 VTAILDKLI 1989
>XP_006721989
          Length = 2823

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VIAILDKLI 9
            V AILDKLI
Sbjct: 1981 VTAILDKLI 1989
>XP_005258041
          Length = 2836

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VIAILDKLI 9
            V AILDKLI
Sbjct: 1950 VTAILDKLI 1958
>XP_006721988
          Length = 2846

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VIAILDKLI 9
            V AILDKLI
Sbjct: 1960 VTAILDKLI 1968
>XP_006721987
          Length = 2849

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VIAILDKLI 9
            V AILDKLI
Sbjct: 1981 VTAILDKLI 1989
>XP_006721986
          Length = 2854

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VIAILDKLI 9
            V AILDKLI
Sbjct: 1968 VTAILDKLI 1976
>XP_005258040
          Length = 2857

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VIAILDKLI 9
            V AILDKLI
Sbjct: 1971 VTAILDKLI 1979
>XP_006721985
          Length = 2867

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VIAILDKLI 9
            V AILDKLI
Sbjct: 1981 VTAILDKLI 1989
>XP_005264773
          Length = 918

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VIAILDKLI 9
           +++ILDKLI
Sbjct: 874 IVSILDKLI 882
>XP_005264772
          Length = 982

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VIAILDKLI 9
           +++ILDKLI
Sbjct: 873 IVSILDKLI 881
>XP_005245809
          Length = 922

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VIAILDKLI 9
           +++ILDKLI
Sbjct: 813 IVSILDKLI 821
>XP_005245808
          Length = 965

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VIAILDKLI 9
           +++ILDKLI
Sbjct: 856 IVSILDKLI 864
>NP_001095139
          Length = 924

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VIAILDKLI 9
           +IA++DKLI
Sbjct: 535 IIAMVDKLI 543
>NP_003857
          Length = 924

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VIAILDKLI 9
           +IA++DKLI
Sbjct: 535 IIAMVDKLI 543
>XP_006714467
          Length = 595

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VIAILDKLI 9
           +IA++DKLI
Sbjct: 544 IIAMVDKLI 552
>XP_005263382
          Length = 753

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VIAILDKLI 9
           +IA++DKLI
Sbjct: 350 IIAMVDKLI 358
>XP_005263381
          Length = 762

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VIAILDKLI 9
           +IA++DKLI
Sbjct: 359 IIAMVDKLI 367
>XP_006714466
          Length = 762

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VIAILDKLI 9
           +IA++DKLI
Sbjct: 359 IIAMVDKLI 367
>XP_005263380
          Length = 809

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VIAILDKLI 9
           +IA++DKLI
Sbjct: 406 IIAMVDKLI 414
>XP_006714465
          Length = 924

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VIAILDKLI 9
           +IA++DKLI
Sbjct: 535 IIAMVDKLI 543
>XP_005263379
          Length = 933

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VIAILDKLI 9
           +IA++DKLI
Sbjct: 544 IIAMVDKLI 552
>XP_006714464
          Length = 938

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VIAILDKLI 9
           +IA++DKLI
Sbjct: 535 IIAMVDKLI 543
>XP_006714463
          Length = 947

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VIAILDKLI 9
           +IA++DKLI
Sbjct: 544 IIAMVDKLI 552
>NP_001275558
          Length = 993

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           ++ ILDK+I
Sbjct: 881 IVGILDKMI 889
>NP_004431
          Length = 998

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           ++ ILDK+I
Sbjct: 886 IVGILDKMI 894
>XP_006715432
          Length = 610

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           ++ ILDK+I
Sbjct: 498 IVGILDKMI 506
>XP_005248726
          Length = 994

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           ++ ILDK+I
Sbjct: 882 IVGILDKMI 890
>NP_002882
          Length = 1273

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IAILDKLI 9
           I +LDKLI
Sbjct: 685 IVVLDKLI 692
>NP_001139120
          Length = 1257

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IAILDKLI 9
           I +LDKLI
Sbjct: 672 IVVLDKLI 679
>NP_036364
          Length = 390

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  VIAILDKLI 9
          V+++LDK+I
Sbjct: 54 VLSLLDKII 62
>NP_004648
          Length = 425

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VIAILDKLI 9
          V+ +LDKL+
Sbjct: 58 VLTLLDKLV 66
>XP_005257299
          Length = 225

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  VIAILDKLI 9
          V+++LDK+I
Sbjct: 54 VLSLLDKII 62
>XP_006720692
          Length = 1270

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IAILDKLI 9
           I +LDKLI
Sbjct: 685 IVVLDKLI 692
>XP_006720691
          Length = 1182

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IAILDKLI 9
           I +LDKLI
Sbjct: 672 IVVLDKLI 679
>XP_006720690
          Length = 1245

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IAILDKLI 9
           I +LDKLI
Sbjct: 672 IVVLDKLI 679
>XP_005254635
          Length = 1280

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IAILDKLI 9
           I +LDKLI
Sbjct: 672 IVVLDKLI 679
>NP_001074001
          Length = 1100

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VIAILDKL 8
           +IA+LDK+
Sbjct: 411 IIALLDKV 418
>NP_689549
          Length = 1066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           V+ ++DKL+
Sbjct: 445 VVKVIDKLL 453
>NP_001122326
          Length = 871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           +I +LDKL+
Sbjct: 604 LIKVLDKLL 612
>NP_001122324
          Length = 875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           +I +LDKL+
Sbjct: 604 LIKVLDKLL 612
>NP_001122325
          Length = 872

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           +I +LDKL+
Sbjct: 605 LIKVLDKLL 613
>NP_056992
          Length = 876

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           +I +LDKL+
Sbjct: 605 LIKVLDKLL 613
>NP_079421
          Length = 1665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    IAILDKL 8
            IA+LDK+
Sbjct: 1554 IAVLDKM 1560
>NP_004429
          Length = 986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           ++ +LDKLI
Sbjct: 874 IVNMLDKLI 882
>NP_758963
          Length = 611

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VIAILDKL 8
           V+AILD L
Sbjct: 603 VVAILDHL 610
>NP_001268695
          Length = 1016

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           ++ +LDKLI
Sbjct: 907 IVNMLDKLI 915
>NP_872272
          Length = 1015

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           ++ +LDKLI
Sbjct: 906 IVNMLDKLI 914
>NP_055918
          Length = 1925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           V+A+LD ++
Sbjct: 415 VVAVLDSVV 423
>NP_004430
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           ++ +LDKLI
Sbjct: 928 IVNMLDKLI 936
>NP_001268694
          Length = 1038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           ++ +LDKLI
Sbjct: 929 IVNMLDKLI 937
>NP_001268696
          Length = 1004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           ++ +LDKLI
Sbjct: 929 IVNMLDKLI 937
>XP_005270233
          Length = 927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   IAILDKL 8
           IA+LDK+
Sbjct: 816 IAVLDKM 822
>XP_005270231
          Length = 1627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    IAILDKL 8
            IA+LDK+
Sbjct: 1516 IAVLDKM 1522
>XP_005270230
          Length = 1627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    IAILDKL 8
            IA+LDK+
Sbjct: 1516 IAVLDKM 1522
>XP_005270229
          Length = 1637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    IAILDKL 8
            IA+LDK+
Sbjct: 1526 IAVLDKM 1532
>XP_005270228
          Length = 1666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    IAILDKL 8
            IA+LDK+
Sbjct: 1555 IAVLDKM 1561
>XP_006716086
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           +I +LDKL+
Sbjct: 378 LIKVLDKLL 386
>XP_005250465
          Length = 878

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           +I +LDKL+
Sbjct: 611 LIKVLDKLL 619
>XP_005250464
          Length = 879

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           +I +LDKL+
Sbjct: 612 LIKVLDKLL 620
>XP_005250463
          Length = 882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           +I +LDKL+
Sbjct: 611 LIKVLDKLL 619
>XP_005250462
          Length = 883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           +I +LDKL+
Sbjct: 612 LIKVLDKLL 620
>XP_005265710
          Length = 874

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           ++ +LDKLI
Sbjct: 765 IVNMLDKLI 773
>XP_005246431
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VIAILDKLI 9
           ++ +LDKLI
Sbjct: 874 IVNMLDKLI 882
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.341    0.163    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 413,168
Number of extensions: 540
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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