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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001121619                                                           18    1482
NP_000258                                                              18    1482
NP_001035957                                                           18    1482
XP_006721991                                                           18    1482
XP_006721990                                                           18    1482
XP_006721989                                                           18    1482
XP_005258041                                                           18    1482
XP_006721988                                                           18    1482
XP_006721987                                                           18    1482
XP_006721986                                                           18    1482
XP_005258040                                                           18    1482
XP_006721985                                                           18    1482
NP_001001668                                                           16    5631
XP_005258968                                                           16    5631
XP_005258967                                                           16    5631
XP_006723273                                                           16    5631
NP_008900                                                              16    7355
XP_006723523                                                           16    7355
XP_006723522                                                           16    7355
XP_006723420                                                           16    7355
XP_006723419                                                           16    7355
XP_006723418                                                           16    7355
XP_006723417                                                           16    7355
NP_001008801                                                           16    7355
NP_001902                                                              15    9605
NP_002011                                                              15    9605
NP_891555                                                              15    9605
NP_071883                                                              15    9605
NP_002362                                                              15    9605
NP_071885                                                              15    9605
NP_071884                                                              15    9605
NP_002431                                                              15    9605
NP_009084                                                              15    9605

>NP_001121619
          Length = 593

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFSRISTML 9
           VFSRIST L
Sbjct: 153 VFSRISTRL 161



>NP_000258
          Length = 2818

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFSRISTML 9
           VFSRIST L
Sbjct: 153 VFSRISTRL 161



>NP_001035957
          Length = 2839

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFSRISTML 9
           VFSRIST L
Sbjct: 153 VFSRISTRL 161



>XP_006721991
          Length = 1632

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFSRISTML 9
           VFSRIST L
Sbjct: 153 VFSRISTRL 161



>XP_006721990
          Length = 2823

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFSRISTML 9
           VFSRIST L
Sbjct: 153 VFSRISTRL 161



>XP_006721989
          Length = 2823

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFSRISTML 9
           VFSRIST L
Sbjct: 153 VFSRISTRL 161



>XP_005258041
          Length = 2836

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFSRISTML 9
           VFSRIST L
Sbjct: 153 VFSRISTRL 161



>XP_006721988
          Length = 2846

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFSRISTML 9
           VFSRIST L
Sbjct: 153 VFSRISTRL 161



>XP_006721987
          Length = 2849

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFSRISTML 9
           VFSRIST L
Sbjct: 153 VFSRISTRL 161



>XP_006721986
          Length = 2854

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFSRISTML 9
           VFSRIST L
Sbjct: 140 VFSRISTRL 148



>XP_005258040
          Length = 2857

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFSRISTML 9
           VFSRIST L
Sbjct: 153 VFSRISTRL 161



>XP_006721985
          Length = 2867

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFSRISTML 9
           VFSRIST L
Sbjct: 153 VFSRISTRL 161



>NP_001001668
          Length = 717

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VFSRISTM 8
           +FS+IST+
Sbjct: 236 IFSKISTL 243



>XP_005258968
          Length = 624

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VFSRISTM 8
           +FS+IST+
Sbjct: 236 IFSKISTL 243



>XP_005258967
          Length = 666

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VFSRISTM 8
           +FS+IST+
Sbjct: 185 IFSKISTL 192



>XP_006723273
          Length = 717

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VFSRISTM 8
           +FS+IST+
Sbjct: 236 IFSKISTL 243



>NP_008900
          Length = 718

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VFSRISTM 8
           VF+R+ST+
Sbjct: 363 VFNRLSTL 370



>XP_006723523
          Length = 469

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VFSRISTM 8
           VF+R+ST+
Sbjct: 310 VFNRLSTL 317



>XP_006723522
          Length = 541

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VFSRISTM 8
           VF+R+ST+
Sbjct: 382 VFNRLSTL 389



>XP_006723420
          Length = 606

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VFSRISTM 8
           VF+R+ST+
Sbjct: 251 VFNRLSTL 258



>XP_006723419
          Length = 634

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VFSRISTM 8
           VF+R+ST+
Sbjct: 363 VFNRLSTL 370



>XP_006723418
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VFSRISTM 8
           VF+R+ST+
Sbjct: 363 VFNRLSTL 370



>XP_006723417
          Length = 704

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VFSRISTM 8
           VF+R+ST+
Sbjct: 349 VFNRLSTL 356



>NP_001008801
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VFSRISTM 8
           VF+R+ST+
Sbjct: 363 VFNRLSTL 370



>NP_001902
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VFSRISTML 9
           VF+R+S+ L
Sbjct: 227 VFTRVSSFL 235



>NP_002011
          Length = 1298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    FSRISTM 8
            FS++STM
Sbjct: 1199 FSQVSTM 1205



>NP_891555
          Length = 1363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    FSRISTM 8
            FS++STM
Sbjct: 1199 FSQVSTM 1205



>NP_071883
          Length = 111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VFSRISTML 9
          VFS I+T+L
Sbjct: 88 VFSYIATLL 96



>NP_002362
          Length = 153

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VFSRISTML 9
           VFS I+T+L
Sbjct: 130 VFSYIATLL 138



>NP_071885
          Length = 55

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VFSRISTML 9
          VFS I+T+L
Sbjct: 32 VFSYIATLL 40



>NP_071884
          Length = 97

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VFSRISTML 9
          VFS I+T+L
Sbjct: 74 VFSYIATLL 82



>NP_002431
          Length = 936

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VFSRIST 7
           +F+RIST
Sbjct: 719 IFTRIST 725



>NP_009084
          Length = 1280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   FSRISTML 9
           FS++ST++
Sbjct: 322 FSKVSTLI 329



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.342    0.140    0.348 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 307,956
Number of extensions: 769
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)