Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001167558                                                           17    3301
NP_858045                                                              17    3301
NP_006525                                                              17    3301
NP_001167559                                                           17    3301
NP_000287                                                              15    9605
NP_001009944                                                           15    9605
NP_079421                                                              15    9605
XP_005255427                                                           15    9605
XP_006720956                                                           15    9605
XP_006720955                                                           15    9605
XP_006720954                                                           15    9605
XP_006720953                                                           15    9605
XP_006720952                                                           15    9605
XP_005270233                                                           15    9605
XP_005270232                                                           15    9605
XP_005270231                                                           15    9605
XP_005270230                                                           15    9605
XP_005270229                                                           15    9605
XP_005270228                                                           15    9605
>NP_001167558
          Length = 1423

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VETSLLSTL 9
           V TSLLSTL
Sbjct: 533 VGTSLLSTL 541
>NP_858045
          Length = 1424

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VETSLLSTL 9
           V TSLLSTL
Sbjct: 533 VGTSLLSTL 541
>NP_006525
          Length = 1420

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VETSLLSTL 9
           V TSLLSTL
Sbjct: 533 VGTSLLSTL 541
>NP_001167559
          Length = 1415

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VETSLLSTL 9
           V TSLLSTL
Sbjct: 543 VGTSLLSTL 551
>NP_000287
          Length = 4302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VETSLLSTL 9
            +ET LLS+L
Sbjct: 3491 METDLLSSL 3499
>NP_001009944
          Length = 4303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VETSLLSTL 9
            +ET LLS+L
Sbjct: 3492 METDLLSSL 3500
>NP_079421
          Length = 1665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VETSLLST 8
           V+TSLLS+
Sbjct: 988 VDTSLLSS 995
>XP_005255427
          Length = 3288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VETSLLSTL 9
            +ET LLS+L
Sbjct: 2477 METDLLSSL 2485
>XP_006720956
          Length = 3895

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VETSLLSTL 9
            +ET LLS+L
Sbjct: 3084 METDLLSSL 3092
>XP_006720955
          Length = 4279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VETSLLSTL 9
            +ET LLS+L
Sbjct: 3468 METDLLSSL 3476
>XP_006720954
          Length = 4334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VETSLLSTL 9
            +ET LLS+L
Sbjct: 3523 METDLLSSL 3531
>XP_006720953
          Length = 4339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VETSLLSTL 9
            +ET LLS+L
Sbjct: 3528 METDLLSSL 3536
>XP_006720952
          Length = 4340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VETSLLSTL 9
            +ET LLS+L
Sbjct: 3529 METDLLSSL 3537
>XP_005270233
          Length = 927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VETSLLST 8
           V+TSLLS+
Sbjct: 250 VDTSLLSS 257
>XP_005270232
          Length = 1535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VETSLLST 8
           V+TSLLS+
Sbjct: 989 VDTSLLSS 996
>XP_005270231
          Length = 1627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VETSLLST 8
           V+TSLLS+
Sbjct: 950 VDTSLLSS 957
>XP_005270230
          Length = 1627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VETSLLST 8
           V+TSLLS+
Sbjct: 950 VDTSLLSS 957
>XP_005270229
          Length = 1637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VETSLLST 8
           V+TSLLS+
Sbjct: 989 VDTSLLSS 996
>XP_005270228
          Length = 1666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VETSLLST 8
           V+TSLLS+
Sbjct: 989 VDTSLLSS 996
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.118    0.258 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 284,425
Number of extensions: 301
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package