Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           17    2528
NP_036462                                                              17    2528
NP_001243397                                                           17    2528
NP_001135920                                                           17    2528
NP_001092882                                                           17    2528
NP_006757                                                              17    2528
NP_001092883                                                           17    2528
NP_001135921                                                           17    2528
XP_006721159                                                           17    2528
XP_005255675                                                           17    2528
XP_005269721                                                           17    2528
XP_005273706                                                           17    2528
NP_001135923                                                           17    2528
NP_114427                                                              17    2528
NP_001135922                                                           17    2528
NP_001186084                                                           17    3301
NP_001186085                                                           17    3301
NP_001186087                                                           17    3301
NP_001186086                                                           17    3301
NP_008998                                                              17    3301
XP_006726849                                                           17    3301
XP_006726848                                                           17    3301
XP_006726847                                                           17    3301
XP_006726846                                                           17    3301
XP_006726845                                                           17    3301
XP_006723592                                                           17    3301
XP_006723591                                                           17    3301
XP_006723590                                                           17    3301
XP_006723589                                                           17    3301
XP_006723588                                                           17    3301
XP_006710119                                                           17    3301
XP_006710118                                                           17    3301
XP_006710117                                                           17    3301
XP_006710116                                                           17    3301
XP_006710115                                                           17    3301
NP_001001954                                                           17    4312
NP_071351                                                              16    5631
NP_001136336                                                           16    5631
XP_006721417                                                           16    5631
XP_006721416                                                           16    5631
NP_892003                                                              16    5631
NP_115564                                                              16    5631
NP_002652                                                              16    7355
NP_005631                                                              16    7355
XP_006722591                                                           16    7355
NP_001005486                                                           16    7355
NP_001129391                                                           15    9605
NP_861450                                                              15    9605
NP_003483                                                              15    9605
NP_689738                                                              15    9605
NP_644807                                                              15    9605
NP_115971                                                              15    9605
NP_001161688                                                           15    9605
NP_001063                                                              15    9605
NP_001161689                                                           15    9605
NP_001161693                                                           15    9605
NP_062564                                                              15    9605
NP_001265497                                                           15    9605
NP_004496                                                              15    9605
XP_003960419                                                           15    9605
XP_005256902                                                           15    9605
XP_005266418                                                           15    9605
XP_003846394                                                           15    9605
XP_006712399                                                           15    9605
XP_006712398                                                           15    9605
XP_006712397                                                           15    9605
XP_006712396                                                           15    9605
XP_006712395                                                           15    9605
XP_006712394                                                           15    9605
XP_005246404                                                           15    9605
XP_003846733                                                           15    9605
NP_277040                                                              15    9605
>NP_001243398
          Length = 1781

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VEPFLFMSL 9
           VEPFLF  L
Sbjct: 529 VEPFLFYVL 537
>NP_036462
          Length = 2073

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VEPFLFMSL 9
           VEPFLF  L
Sbjct: 821 VEPFLFYVL 829
>NP_001243397
          Length = 1890

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VEPFLFMSL 9
           VEPFLF  L
Sbjct: 638 VEPFLFYVL 646
>NP_001135920
          Length = 528

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PFLFMSL 9
           PFLF+SL
Sbjct: 368 PFLFLSL 374
>NP_001092882
          Length = 2004

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VEPFLFMSL 9
           VEPFLF  L
Sbjct: 610 VEPFLFYVL 618
>NP_006757
          Length = 2004

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VEPFLFMSL 9
           VEPFLF  L
Sbjct: 610 VEPFLFYVL 618
>NP_001092883
          Length = 2004

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VEPFLFMSL 9
           VEPFLF  L
Sbjct: 610 VEPFLFYVL 618
>NP_001135921
          Length = 454

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PFLFMSL 9
           PFLF+SL
Sbjct: 294 PFLFLSL 300
>XP_006721159
          Length = 521

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PFLFMSL 9
           PFLF+SL
Sbjct: 361 PFLFLSL 367
>XP_005255675
          Length = 573

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PFLFMSL 9
           PFLF+SL
Sbjct: 413 PFLFLSL 419
>XP_005269721
          Length = 2073

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VEPFLFMSL 9
           VEPFLF  L
Sbjct: 821 VEPFLFYVL 829
>XP_005273706
          Length = 1997

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VEPFLFMSL 9
           VEPFLF  L
Sbjct: 603 VEPFLFYVL 611
>NP_001135923
          Length = 476

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PFLFMSL 9
           PFLF+SL
Sbjct: 316 PFLFLSL 322
>NP_114427
          Length = 528

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PFLFMSL 9
           PFLF+SL
Sbjct: 368 PFLFLSL 374
>NP_001135922
          Length = 455

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PFLFMSL 9
           PFLF+SL
Sbjct: 295 PFLFLSL 301
>NP_001186084
          Length = 581

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VEPFLF 6
           VEPFLF
Sbjct: 408 VEPFLF 413
>NP_001186085
          Length = 472

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VEPFLF 6
           VEPFLF
Sbjct: 299 VEPFLF 304
>NP_001186087
          Length = 442

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VEPFLF 6
           VEPFLF
Sbjct: 269 VEPFLF 274
>NP_001186086
          Length = 501

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VEPFLF 6
           VEPFLF
Sbjct: 328 VEPFLF 333
>NP_008998
          Length = 611

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VEPFLF 6
           VEPFLF
Sbjct: 438 VEPFLF 443
>XP_006726849
          Length = 138

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  EPFLFMSL 9
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006726848
          Length = 139

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  EPFLFMSL 9
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006726847
          Length = 141

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  EPFLFMSL 9
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006726846
          Length = 144

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  EPFLFMSL 9
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006726845
          Length = 150

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  EPFLFMSL 9
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006723592
          Length = 138

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  EPFLFMSL 9
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006723591
          Length = 139

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  EPFLFMSL 9
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006723590
          Length = 141

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  EPFLFMSL 9
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006723589
          Length = 144

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  EPFLFMSL 9
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006723588
          Length = 150

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  EPFLFMSL 9
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006710119
          Length = 138

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  EPFLFMSL 9
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006710118
          Length = 139

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  EPFLFMSL 9
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006710117
          Length = 141

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  EPFLFMSL 9
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006710116
          Length = 144

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  EPFLFMSL 9
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>XP_006710115
          Length = 150

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  EPFLFMSL 9
          EPFL MSL
Sbjct: 5  EPFLKMSL 12
>NP_001001954
          Length = 324

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PFLFMSL 9
           PF+FM+L
Sbjct: 317 PFIFMTL 323
>NP_071351
          Length = 2752

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    PFLFMSL 9
            P LFMSL
Sbjct: 2419 PLLFMSL 2425
>NP_001136336
          Length = 2521

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    PFLFMSL 9
            P LFMSL
Sbjct: 2190 PLLFMSL 2196
>XP_006721417
          Length = 2497

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    PFLFMSL 9
            P LFMSL
Sbjct: 2166 PLLFMSL 2172
>XP_006721416
          Length = 2504

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    PFLFMSL 9
            P LFMSL
Sbjct: 2173 PLLFMSL 2179
>NP_892003
          Length = 467

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VEPFLFMSL 9
           VEPF+F  L
Sbjct: 280 VEPFVFYIL 288
>NP_115564
          Length = 458

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VEPFLFMSL 9
           VEPF+F  L
Sbjct: 280 VEPFVFYIL 288
>NP_002652
          Length = 1265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   EPFLFM 7
           EPFLF+
Sbjct: 282 EPFLFV 287
>NP_005631
          Length = 862

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   EPFLFM 7
           EPFLF+
Sbjct: 652 EPFLFI 657
>XP_006722591
          Length = 827

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   EPFLFM 7
           EPFLF+
Sbjct: 652 EPFLFI 657
>NP_001005486
          Length = 348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  VEPFLFMS 8
          ++PFLF++
Sbjct: 47 LQPFLFLT 54
>NP_001129391
          Length = 463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  VEPFLFMS 8
          VEP +F+S
Sbjct: 6  VEPAIFLS 13
>NP_861450
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  VEPFLFMS 8
          VEP +F+S
Sbjct: 6  VEPAIFLS 13
>NP_003483
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PFLFMSL 9
           P+LF+SL
Sbjct: 139 PWLFLSL 145
>NP_689738
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EPFLFMSL 9
           EP +FM+L
Sbjct: 260 EPSMFMNL 267
>NP_644807
          Length = 548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   EPFLFMS 8
           EPFL+ S
Sbjct: 237 EPFLYSS 243
>NP_115971
          Length = 1604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EPFLFMSL 9
           +PF F+SL
Sbjct: 904 DPFNFLSL 911
>NP_001161688
          Length = 395

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EPFLFMSL 9
           EP +FM+L
Sbjct: 260 EPSMFMNL 267
>NP_001063
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VEPFLFMSL 9
           +EP+LF  L
Sbjct: 217 LEPYLFYCL 225
>NP_001161689
          Length = 550

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EPFLFMSL 9
           EP +FM+L
Sbjct: 260 EPSMFMNL 267
>NP_001161693
          Length = 1820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EPFLFMSL 9
           EP +FM+L
Sbjct: 260 EPSMFMNL 267
>NP_062564
          Length = 169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   VEPFLF 6
           V+PFLF
Sbjct: 114 VKPFLF 119
>NP_001265497
          Length = 134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  VEPFLF 6
          V+PFLF
Sbjct: 79 VKPFLF 84
>NP_004496
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EPFLFMSL 9
           +PF F+SL
Sbjct: 702 DPFNFLSL 709
>XP_003960419
          Length = 209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  VEPFLF 6
          V+PFLF
Sbjct: 40 VKPFLF 45
>XP_005256902
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EPFLFMSL 9
           +PF F+SL
Sbjct: 702 DPFNFLSL 709
>XP_005266418
          Length = 463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  VEPFLFMS 8
          VEP +F+S
Sbjct: 6  VEPAIFLS 13
>XP_003846394
          Length = 209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  VEPFLF 6
          V+PFLF
Sbjct: 40 VKPFLF 45
>XP_006712399
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EPFLFMSL 9
           EP +FM+L
Sbjct: 260 EPSMFMNL 267
>XP_006712398
          Length = 467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EPFLFMSL 9
           EP +FM+L
Sbjct: 260 EPSMFMNL 267
>XP_006712397
          Length = 471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EPFLFMSL 9
           EP +FM+L
Sbjct: 260 EPSMFMNL 267
>XP_006712396
          Length = 471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EPFLFMSL 9
           EP +FM+L
Sbjct: 260 EPSMFMNL 267
>XP_006712395
          Length = 599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EPFLFMSL 9
           EP +FM+L
Sbjct: 260 EPSMFMNL 267
>XP_006712394
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EPFLFMSL 9
           EP +FM+L
Sbjct: 260 EPSMFMNL 267
>XP_005246404
          Length = 1821

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EPFLFMSL 9
           EP +FM+L
Sbjct: 260 EPSMFMNL 267
>XP_003846733
          Length = 209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  VEPFLF 6
          V+PFLF
Sbjct: 40 VKPFLF 45
>NP_277040
          Length = 397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 2   EPFLF 6
           EPFLF
Sbjct: 210 EPFLF 214
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.342    0.154    0.459 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 525,361
Number of extensions: 563
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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