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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              20     390
XP_005271621                                                           20     390
XP_006718907                                                           20     390
XP_006718906                                                           20     390
XP_005271619                                                           20     390
XP_005271618                                                           20     390
NP_001139150                                                           17    2528
NP_775936                                                              17    2528
XP_006714651                                                           17    2528
NP_001139669                                                           16    5631
NP_001035519                                                           16    7355
XP_005266415                                                           16    7355
XP_005266414                                                           16    7355
NP_005048                                                              15    9605
NP_001007098                                                           15    9605
NP_001180201                                                           15    9605
NP_001018075                                                           15    9605
NP_006171                                                              15    9605
NP_001018074                                                           15    9605
NP_001180202                                                           15    9605
NP_001018076                                                           15    9605
NP_665809                                                              15    9605
NP_114148                                                              15    9605
NP_004762                                                              15    9605
XP_005252064                                                           15    9605
XP_005252063                                                           15    9605
XP_006717183                                                           15    9605
XP_005252061                                                           15    9605
XP_005252060                                                           15    9605
XP_005252058                                                           15    9605
XP_005247302                                                           15    9605
XP_006711539                                                           15    9605
XP_005245458                                                           15    9605
XP_005245457                                                           15    9605
XP_005245456                                                           15    9605
XP_005245455                                                           15    9605

>NP_000042
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VEDQSSMNV 9
           VEDQSSMN+
Sbjct: 849 VEDQSSMNL 857



>XP_005271621
          Length = 2708

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VEDQSSMNV 9
           VEDQSSMN+
Sbjct: 501 VEDQSSMNL 509



>XP_006718907
          Length = 3050

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VEDQSSMNV 9
           VEDQSSMN+
Sbjct: 849 VEDQSSMNL 857



>XP_006718906
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VEDQSSMNV 9
           VEDQSSMN+
Sbjct: 849 VEDQSSMNL 857



>XP_005271619
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VEDQSSMNV 9
           VEDQSSMN+
Sbjct: 849 VEDQSSMNL 857



>XP_005271618
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VEDQSSMNV 9
           VEDQSSMN+
Sbjct: 849 VEDQSSMNL 857



>NP_001139150
          Length = 1275

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VEDQSSMNV 9
           VED SSM+V
Sbjct: 149 VEDNSSMDV 157



>NP_775936
          Length = 324

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VEDQSSMNV 9
           VED SSM+V
Sbjct: 149 VEDNSSMDV 157



>XP_006714651
          Length = 1280

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VEDQSSMNV 9
           VED SSM+V
Sbjct: 149 VEDNSSMDV 157



>NP_001139669
          Length = 7081

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    EDQSSMNV 9
            ED+S++NV
Sbjct: 3842 EDESNLNV 3849



>NP_001035519
          Length = 1159

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   VEDQSSMNV 9
           VE++++MNV
Sbjct: 774 VEERNAMNV 782



>XP_005266415
          Length = 1158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   VEDQSSMNV 9
           VE++++MNV
Sbjct: 774 VEERNAMNV 782



>XP_005266414
          Length = 1159

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   VEDQSSMNV 9
           VE++++MNV
Sbjct: 774 VEERNAMNV 782



>NP_005048
          Length = 538

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VEDQSSMNV 9
           V+D S +NV
Sbjct: 147 VDDDSDLNV 155



>NP_001007098
          Length = 477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EDQSSMNV 9
           EDQ S+N+
Sbjct: 274 EDQDSVNL 281



>NP_001180201
          Length = 500

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VEDQSSMNV 9
           V+D S +NV
Sbjct: 147 VDDDSDLNV 155



>NP_001018075
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EDQSSMNV 9
           EDQ S+N+
Sbjct: 274 EDQDSVNL 281



>NP_006171
          Length = 838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EDQSSMNV 9
           EDQ S+N+
Sbjct: 274 EDQDSVNL 281



>NP_001018074
          Length = 822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EDQSSMNV 9
           EDQ S+N+
Sbjct: 274 EDQDSVNL 281



>NP_001180202
          Length = 410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VEDQSSMNV 9
          V+D S +NV
Sbjct: 20 VDDDSDLNV 28



>NP_001018076
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EDQSSMNV 9
           EDQ S+N+
Sbjct: 274 EDQDSVNL 281



>NP_665809
          Length = 371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   EDQSSMN 8
           ED+S MN
Sbjct: 107 EDESGMN 113



>NP_114148
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   EDQSSMN 8
           ED+S MN
Sbjct: 186 EDESGMN 192



>NP_004762
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  DQSSMNV 9
          DQ++MNV
Sbjct: 88 DQTTMNV 94



>XP_005252064
          Length = 477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EDQSSMNV 9
           EDQ S+N+
Sbjct: 274 EDQDSVNL 281



>XP_005252063
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EDQSSMNV 9
           EDQ S+N+
Sbjct: 274 EDQDSVNL 281



>XP_006717183
          Length = 554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EDQSSMNV 9
           EDQ S+N+
Sbjct: 274 EDQDSVNL 281



>XP_005252061
          Length = 838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EDQSSMNV 9
           EDQ S+N+
Sbjct: 274 EDQDSVNL 281



>XP_005252060
          Length = 838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EDQSSMNV 9
           EDQ S+N+
Sbjct: 274 EDQDSVNL 281



>XP_005252058
          Length = 838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EDQSSMNV 9
           EDQ S+N+
Sbjct: 274 EDQDSVNL 281



>XP_005247302
          Length = 2248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   EDQSSMNV 9
           ED+++MN+
Sbjct: 736 EDKNNMNI 743



>XP_006711539
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VEDQSSMNV 9
           V+D S +NV
Sbjct: 182 VDDDSDLNV 190



>XP_005245458
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VEDQSSMNV 9
           V+D S +NV
Sbjct: 147 VDDDSDLNV 155



>XP_005245457
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VEDQSSMNV 9
           V+D S +NV
Sbjct: 182 VDDDSDLNV 190



>XP_005245456
          Length = 572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VEDQSSMNV 9
           V+D S +NV
Sbjct: 182 VDDDSDLNV 190



>XP_005245455
          Length = 573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VEDQSSMNV 9
           V+D S +NV
Sbjct: 182 VDDDSDLNV 190



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.293    0.108    0.247 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 465,177
Number of extensions: 573
Number of successful extensions: 36
Number of sequences better than 10000.0: 36
Number of HSP's gapped: 36
Number of HSP's successfully gapped: 36
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)