Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004963                                                              20     390
XP_005251512                                                           20     390
NP_003945                                                              17    4312
NP_001128302                                                           16    5631
NP_060121                                                              16    5631
NP_001128303                                                           16    5631
NP_001128304                                                           16    5631
XP_005267096                                                           16    5631
XP_006715570                                                           16    5631
NP_001018066                                                           16    7355
NP_003374                                                              16    7355
XP_006716928                                                           16    7355
XP_006716927                                                           16    7355
NP_001268669                                                           15    9605
NP_114113                                                              15    9605
NP_079411                                                              15    9605
NP_001268668                                                           15    9605
NP_004997                                                              15    9605
NP_113652                                                              15    9605
NP_001186913                                                           15    9605
XP_006722614                                                           15    9605
XP_005258412                                                           15    9605
XP_005258411                                                           15    9605
XP_005258409                                                           15    9605
XP_005258408                                                           15    9605
XP_006722613                                                           15    9605
XP_005258407                                                           15    9605
XP_005258406                                                           15    9605
XP_005258405                                                           15    9605
XP_005258404                                                           15    9605
XP_005258403                                                           15    9605
XP_005268179                                                           15    9605
XP_005268177                                                           15    9605
XP_006720334                                                           15    9605
XP_006720333                                                           15    9605
XP_006720332                                                           15    9605
XP_005268175                                                           15    9605
XP_005268171                                                           15    9605
XP_006720331                                                           15    9605
XP_006720330                                                           15    9605
XP_006720329                                                           15    9605
XP_005268172                                                           15    9605
XP_006720328                                                           15    9605
NP_001186911                                                           15    9605
NP_001186910                                                           15    9605
NP_001186912                                                           15    9605
>NP_004963
          Length = 1132

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VDQIRNNMA 9
            VDQIR+NMA
Sbjct: 1123 VDQIRDNMA 1131
>XP_005251512
          Length = 1132

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VDQIRNNMA 9
            VDQIR+NMA
Sbjct: 1123 VDQIRDNMA 1131
>NP_003945
          Length = 947

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VDQIRNNMA 9
           +DQI NN+A
Sbjct: 114 LDQIPNNVA 122
>NP_001128302
          Length = 1196

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VDQIRNN 7
           VD+I+NN
Sbjct: 455 VDEIKNN 461
>NP_060121
          Length = 1196

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VDQIRNN 7
           VD+I+NN
Sbjct: 455 VDEIKNN 461
>NP_001128303
          Length = 1196

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VDQIRNN 7
           VD+I+NN
Sbjct: 455 VDEIKNN 461
>NP_001128304
          Length = 1053

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VDQIRNN 7
           VD+I+NN
Sbjct: 455 VDEIKNN 461
>XP_005267096
          Length = 1168

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VDQIRNN 7
           VD+I+NN
Sbjct: 455 VDEIKNN 461
>XP_006715570
          Length = 1179

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VDQIRNN 7
           VD+I+NN
Sbjct: 455 VDEIKNN 461
>NP_001018066
          Length = 845

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VDQIRNNMA 9
           V+Q+RN +A
Sbjct: 465 VEQLRNTVA 473
>NP_003374
          Length = 873

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VDQIRNNMA 9
           V+Q+RN +A
Sbjct: 465 VEQLRNTVA 473
>XP_006716928
          Length = 850

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VDQIRNNMA 9
           V+Q+RN +A
Sbjct: 470 VEQLRNTVA 478
>XP_006716927
          Length = 878

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VDQIRNNMA 9
           V+Q+RN +A
Sbjct: 470 VEQLRNTVA 478
>NP_001268669
          Length = 1622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    VDQIRNN 7
            +DQ+ NN
Sbjct: 1266 IDQLENN 1272
>NP_114113
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   VDQIRNNM 8
           +DQ+++NM
Sbjct: 391 LDQLKDNM 398
>NP_079411
          Length = 1439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    VDQIRNN 7
            +DQ+ NN
Sbjct: 1091 IDQLENN 1097
>NP_001268668
          Length = 1422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    VDQIRNN 7
            +DQ+ NN
Sbjct: 1074 IDQLENN 1080
>NP_004997
          Length = 727

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   VDQIRNNM 8
           +DQ+RN +
Sbjct: 639 LDQVRNRL 646
>NP_113652
          Length = 549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VDQIRNNMA 9
          ++QIRN +A
Sbjct: 30 LEQIRNRVA 38
>NP_001186913
          Length = 741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   VDQIRNNM 8
           +DQ+RN +
Sbjct: 653 LDQVRNRL 660
>XP_006722614
          Length = 1589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    VDQIRNN 7
            +DQ+ NN
Sbjct: 1241 IDQLENN 1247
>XP_005258412
          Length = 1401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    VDQIRNN 7
            +DQ+ NN
Sbjct: 1053 IDQLENN 1059
>XP_005258411
          Length = 1409

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    VDQIRNN 7
            +DQ+ NN
Sbjct: 1053 IDQLENN 1059
>XP_005258409
          Length = 1430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    VDQIRNN 7
            +DQ+ NN
Sbjct: 1074 IDQLENN 1080
>XP_005258408
          Length = 1447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    VDQIRNN 7
            +DQ+ NN
Sbjct: 1091 IDQLENN 1097
>XP_006722613
          Length = 1523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    VDQIRNN 7
            +DQ+ NN
Sbjct: 1167 IDQLENN 1173
>XP_005258407
          Length = 1533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    VDQIRNN 7
            +DQ+ NN
Sbjct: 1266 IDQLENN 1272
>XP_005258406
          Length = 1559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    VDQIRNN 7
            +DQ+ NN
Sbjct: 1203 IDQLENN 1209
>XP_005258405
          Length = 1597

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    VDQIRNN 7
            +DQ+ NN
Sbjct: 1241 IDQLENN 1247
>XP_005258404
          Length = 1605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    VDQIRNN 7
            +DQ+ NN
Sbjct: 1249 IDQLENN 1255
>XP_005258403
          Length = 1614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    VDQIRNN 7
            +DQ+ NN
Sbjct: 1266 IDQLENN 1272
>XP_005268179
          Length = 315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VDQIRNNMA 9
          ++QIRN +A
Sbjct: 30 LEQIRNRVA 38
>XP_005268177
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VDQIRNNMA 9
          ++QIRN +A
Sbjct: 30 LEQIRNRVA 38
>XP_006720334
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VDQIRNNMA 9
          ++QIRN +A
Sbjct: 30 LEQIRNRVA 38
>XP_006720333
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VDQIRNNMA 9
          ++QIRN +A
Sbjct: 30 LEQIRNRVA 38
>XP_006720332
          Length = 455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VDQIRNNMA 9
          ++QIRN +A
Sbjct: 30 LEQIRNRVA 38
>XP_005268175
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VDQIRNNMA 9
          ++QIRN +A
Sbjct: 30 LEQIRNRVA 38
>XP_005268171
          Length = 549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VDQIRNNMA 9
          ++QIRN +A
Sbjct: 30 LEQIRNRVA 38
>XP_006720331
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VDQIRNNMA 9
          ++QIRN +A
Sbjct: 30 LEQIRNRVA 38
>XP_006720330
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VDQIRNNMA 9
          ++QIRN +A
Sbjct: 30 LEQIRNRVA 38
>XP_006720329
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VDQIRNNMA 9
          ++QIRN +A
Sbjct: 30 LEQIRNRVA 38
>XP_005268172
          Length = 587

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VDQIRNNMA 9
          ++QIRN +A
Sbjct: 30 LEQIRNRVA 38
>XP_006720328
          Length = 587

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VDQIRNNMA 9
          ++QIRN +A
Sbjct: 30 LEQIRNRVA 38
>NP_001186911
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   VDQIRNNM 8
           +DQ+RN +
Sbjct: 528 LDQVRNRL 535
>NP_001186910
          Length = 691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   VDQIRNNM 8
           +DQ+RN +
Sbjct: 603 LDQVRNRL 610
>NP_001186912
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   VDQIRNNM 8
           +DQ+RN +
Sbjct: 582 LDQVRNRL 589
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.128    0.337 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 462,996
Number of extensions: 892
Number of successful extensions: 46
Number of sequences better than 10000.0: 46
Number of HSP's gapped: 46
Number of HSP's successfully gapped: 46
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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