Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

• Home Page
• Cancer-specific
• Epitope Search
• Data Retrieval
• Browse Gene
• Browse Tissue
• Sequence Similarity
• Partially Personalized
• Submit a Protein
• Vaccine Target
• Proteome Data
• NGS data
• BLAST & Predict
• Fully Personalized
• Proteins Pair
• Proteome Pair
• Advanced Tools
• Epitope Mapping
• Cross Reactivity
• Important Information
• Acknowledgement
• Algorithm
• Help
• Developers
• Contact

Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_116165                                                              16    5631
NP_001269877                                                           16    5631
XP_005269685                                                           16    5631
XP_005269684                                                           16    5631
XP_005269683                                                           16    5631
XP_005269681                                                           16    5631
XP_006717770                                                           16    5631
XP_005269679                                                           16    5631
NP_004658                                                              16    7355
NP_001004334                                                           16    7355
NP_056046                                                              16    7355
XP_006720790                                                           16    7355
XP_005268334                                                           16    7355
XP_005268333                                                           16    7355
XP_006720789                                                           16    7355

>NP_116165
          Length = 2540

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VDLRQSSV 8
           VDL QSSV
Sbjct: 572 VDLTQSSV 579



>NP_001269877
          Length = 2358

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VDLRQSSV 8
           VDL QSSV
Sbjct: 390 VDLTQSSV 397



>XP_005269685
          Length = 1700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VDLRQSSV 8
           VDL QSSV
Sbjct: 572 VDLTQSSV 579



>XP_005269684
          Length = 2032

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VDLRQSSV 8
           VDL QSSV
Sbjct: 572 VDLTQSSV 579



>XP_005269683
          Length = 2252

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VDLRQSSV 8
           VDL QSSV
Sbjct: 284 VDLTQSSV 291



>XP_005269681
          Length = 2321

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VDLRQSSV 8
           VDL QSSV
Sbjct: 353 VDLTQSSV 360



>XP_006717770
          Length = 2358

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VDLRQSSV 8
           VDL QSSV
Sbjct: 390 VDLTQSSV 397



>XP_005269679
          Length = 2502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VDLRQSSV 8
           VDL QSSV
Sbjct: 534 VDLTQSSV 541



>NP_004658
          Length = 4834

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VDLRQSSV 8
           +DLRQ++V
Sbjct: 387 IDLRQTAV 394



>NP_001004334
          Length = 2367

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DLRQSSVQ 9
           D+R+SSV+
Sbjct: 117 DIRESSVE 124



>NP_056046
          Length = 1436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VDLRQSSV 8
           V+L+QSSV
Sbjct: 255 VELKQSSV 262



>XP_006720790
          Length = 4748

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VDLRQSSV 8
           +DLRQ++V
Sbjct: 301 IDLRQTAV 308



>XP_005268334
          Length = 4796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VDLRQSSV 8
           +DLRQ++V
Sbjct: 349 IDLRQTAV 356



>XP_005268333
          Length = 4796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VDLRQSSV 8
           +DLRQ++V
Sbjct: 349 IDLRQTAV 356



>XP_006720789
          Length = 4829

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VDLRQSSV 8
           +DLRQ++V
Sbjct: 387 IDLRQTAV 394



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.121    0.280 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 341,769
Number of extensions: 353
Number of successful extensions: 15
Number of sequences better than 10000.0: 15
Number of HSP's gapped: 15
Number of HSP's successfully gapped: 15
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)