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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004351                                                              20     390
NP_001017408                                                           17    3301
NP_065132                                                              17    3301
NP_036300                                                              17    4312
NP_001006608                                                           16    5631
NP_955372                                                              16    5631
NP_055649                                                              16    5631
XP_006725346                                                           16    5631
XP_005275722                                                           16    5631
XP_005275721                                                           16    5631
XP_006725344                                                           16    5631
XP_006725343                                                           16    5631
XP_006725342                                                           16    5631
XP_005275717                                                           16    5631
XP_005257944                                                           16    5631
XP_005257941                                                           16    5631
XP_005257940                                                           16    5631
XP_005257939                                                           16    5631
XP_006722272                                                           16    5631
XP_005257937                                                           16    5631
XP_005257936                                                           16    5631
XP_006722271                                                           16    5631
NP_149094                                                              16    7355
NP_004870                                                              15    9605
NP_001277064                                                           15    9605
NP_008862                                                              15    9605
NP_001273164                                                           15    9605
NP_001273166                                                           15    9605
NP_001273163                                                           15    9605
NP_001230588                                                           15    9605
NP_001273162                                                           15    9605
NP_703150                                                              15    9605
NP_001273165                                                           15    9605
NP_001112362                                                           15    9605
NP_002055                                                              15    9605
NP_001138740                                                           15    9605
NP_001230587                                                           15    9605
XP_005253374                                                           15    9605
XP_005253372                                                           15    9605
XP_006715959                                                           15    9605
NP_001135389                                                           15    9605

>NP_004351
          Length = 882

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VCRKAQSVE 9
           VCRKAQ VE
Sbjct: 694 VCRKAQPVE 702



>NP_001017408
          Length = 454

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VCRKAQSV 8
          +C KAQSV
Sbjct: 80 LCHKAQSV 87



>NP_065132
          Length = 462

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VCRKAQSV 8
          +C KAQSV
Sbjct: 80 LCHKAQSV 87



>NP_036300
          Length = 296

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   CRKAQSVE 9
           CRKAQ ++
Sbjct: 176 CRKAQVID 183



>NP_001006608
          Length = 1700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CRKAQSVE 9
           C K QS+E
Sbjct: 922 CNKIQSIE 929



>NP_955372
          Length = 1634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CRKAQSVE 9
           C K QS+E
Sbjct: 922 CNKIQSIE 929



>NP_055649
          Length = 1700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CRKAQSVE 9
           C K QS+E
Sbjct: 922 CNKIQSIE 929



>XP_006725346
          Length = 839

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  CRKAQSVE 9
          C K QS+E
Sbjct: 61 CNKIQSIE 68



>XP_005275722
          Length = 969

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CRKAQSVE 9
           C K QS+E
Sbjct: 922 CNKIQSIE 929



>XP_005275721
          Length = 1018

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CRKAQSVE 9
           C K QS+E
Sbjct: 922 CNKIQSIE 929



>XP_006725344
          Length = 1606

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CRKAQSVE 9
           C K QS+E
Sbjct: 828 CNKIQSIE 835



>XP_006725343
          Length = 1635

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CRKAQSVE 9
           C K QS+E
Sbjct: 922 CNKIQSIE 929



>XP_006725342
          Length = 1651

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CRKAQSVE 9
           C K QS+E
Sbjct: 922 CNKIQSIE 929



>XP_005275717
          Length = 1665

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CRKAQSVE 9
           C K QS+E
Sbjct: 922 CNKIQSIE 929



>XP_005257944
          Length = 839

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  CRKAQSVE 9
          C K QS+E
Sbjct: 61 CNKIQSIE 68



>XP_005257941
          Length = 969

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CRKAQSVE 9
           C K QS+E
Sbjct: 922 CNKIQSIE 929



>XP_005257940
          Length = 1018

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CRKAQSVE 9
           C K QS+E
Sbjct: 922 CNKIQSIE 929



>XP_005257939
          Length = 1606

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CRKAQSVE 9
           C K QS+E
Sbjct: 828 CNKIQSIE 835



>XP_006722272
          Length = 1635

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CRKAQSVE 9
           C K QS+E
Sbjct: 922 CNKIQSIE 929



>XP_005257937
          Length = 1651

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CRKAQSVE 9
           C K QS+E
Sbjct: 922 CNKIQSIE 929



>XP_005257936
          Length = 1665

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CRKAQSVE 9
           C K QS+E
Sbjct: 922 CNKIQSIE 929



>XP_006722271
          Length = 1700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CRKAQSVE 9
           C K QS+E
Sbjct: 922 CNKIQSIE 929



>NP_149094
          Length = 686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VCRKAQSVE 9
           +C+K +S+E
Sbjct: 429 LCKKLRSIE 437



>NP_004870
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  RKAQSVE 9
          R+AQS+E
Sbjct: 52 RRAQSIE 58



>NP_001277064
          Length = 326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  RKAQSVE 9
          R+AQS+E
Sbjct: 38 RRAQSIE 44



>NP_008862
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VCRKAQSVE 9
           +C+ A+SVE
Sbjct: 110 LCKVAKSVE 118



>NP_001273164
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VCRKAQSVE 9
           +C+ A+SVE
Sbjct: 111 LCKIAESVE 119



>NP_001273166
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VCRKAQSVE 9
           +C+ A+SVE
Sbjct: 149 LCKIAESVE 157



>NP_001273163
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VCRKAQSVE 9
           +C+ A+SVE
Sbjct: 111 LCKIAESVE 119



>NP_001230588
          Length = 106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2  CRKAQSV 8
          CR+AQ +
Sbjct: 26 CRRAQEI 32



>NP_001273162
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VCRKAQSVE 9
           +C+ A+SVE
Sbjct: 134 LCKIAESVE 142



>NP_703150
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VCRKAQSVE 9
           +C+ A+SVE
Sbjct: 134 LCKIAESVE 142



>NP_001273165
          Length = 411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VCRKAQSVE 9
          +C+ A+SVE
Sbjct: 25 LCKIAESVE 33



>NP_001112362
          Length = 106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2  CRKAQSV 8
          CR+AQ +
Sbjct: 26 CRRAQEI 32



>NP_002055
          Length = 106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2  CRKAQSV 8
          CR+AQ +
Sbjct: 26 CRRAQEI 32



>NP_001138740
          Length = 392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CRKAQSVE 9
           C K QS+E
Sbjct: 161 CVKVQSIE 168



>NP_001230587
          Length = 106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2  CRKAQSV 8
          CR+AQ +
Sbjct: 26 CRRAQEI 32



>XP_005253374
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VCRKAQSVE 9
           +C+ A+SVE
Sbjct: 111 LCKIAESVE 119



>XP_005253372
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VCRKAQSVE 9
           +C+ A+SVE
Sbjct: 111 LCKIAESVE 119



>XP_006715959
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CRKAQSVE 9
           C K QS+E
Sbjct: 161 CVKVQSIE 168



>NP_001135389
          Length = 1335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   CRKAQSVE 9
           C KAQS E
Sbjct: 556 CGKAQSPE 563



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.121    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 443,897
Number of extensions: 344
Number of successful extensions: 41
Number of sequences better than 10000.0: 41
Number of HSP's gapped: 41
Number of HSP's successfully gapped: 41
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)