Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006209                                                              19     869
XP_006713721                                                           19     869
NP_001269356                                                           18    1135
NP_001269355                                                           18    1135
NP_002640                                                              18    1135
XP_005250500                                                           18    1135
NP_005017                                                              17    2528
NP_002636                                                              17    2528
XP_005253037                                                           17    2528
XP_005253036                                                           17    2528
XP_005253035                                                           17    2528
XP_005253034                                                           17    2528
XP_005245315                                                           17    2528
XP_006711447                                                           17    2528
XP_005245314                                                           17    2528
XP_006710753                                                           17    2528
XP_005263530                                                           17    2528
XP_006710752                                                           17    2528
XP_006710751                                                           17    2528
XP_006710750                                                           17    2528
XP_006710749                                                           17    2528
NP_002637                                                              17    2528
NP_001275701                                                           17    3301
NP_004561                                                              17    3301
NP_001275703                                                           17    3301
XP_005253450                                                           17    3301
XP_006719151                                                           17    3301
NP_116207                                                              16    5631
NP_005674                                                              15    9605
NP_001161957                                                           15    9605
NP_001161954                                                           15    9605
NP_001161951                                                           15    9605
NP_001161952                                                           15    9605
NP_073749                                                              15    9605
NP_001161950                                                           15    9605
NP_002638                                                              15    9605
NP_001107604                                                           15    9605
NP_036537                                                              15    9605
XP_006721734                                                           15    9605
XP_005247009                                                           15    9605
XP_006712765                                                           15    9605
XP_006712764                                                           15    9605
XP_005246844                                                           15    9605
XP_006712763                                                           15    9605
XP_006712762                                                           15    9605
XP_006712761                                                           15    9605
XP_005263494                                                           15    9605
NP_001153879                                                           15    9605
NP_612472                                                              15    9605
>NP_006209
          Length = 1068

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   VATFILGI 8
           VATFILGI
Sbjct: 906 VATFILGI 913
>XP_006713721
          Length = 1068

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   VATFILGI 8
           VATFILGI
Sbjct: 906 VATFILGI 913
>NP_001269356
          Length = 1102

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   VATFILGI 8
           VATF+LGI
Sbjct: 937 VATFVLGI 944
>NP_001269355
          Length = 1102

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   VATFILGI 8
           VATF+LGI
Sbjct: 937 VATFVLGI 944
>NP_002640
          Length = 1102

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   VATFILGI 8
           VATF+LGI
Sbjct: 937 VATFVLGI 944
>XP_005250500
          Length = 1102

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   VATFILGI 8
           VATF+LGI
Sbjct: 937 VATFVLGI 944
>NP_005017
          Length = 1044

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VATFILGI 8
           VAT++LGI
Sbjct: 884 VATYVLGI 891
>NP_002636
          Length = 1686

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    VATFILGI 8
            VAT++LGI
Sbjct: 1241 VATYVLGI 1248
>XP_005253037
          Length = 1306

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VATFILGI 8
           VAT++LGI
Sbjct: 861 VATYVLGI 868
>XP_005253036
          Length = 1686

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    VATFILGI 8
            VAT++LGI
Sbjct: 1241 VATYVLGI 1248
>XP_005253035
          Length = 1686

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    VATFILGI 8
            VAT++LGI
Sbjct: 1241 VATYVLGI 1248
>XP_005253034
          Length = 1686

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    VATFILGI 8
            VAT++LGI
Sbjct: 1241 VATYVLGI 1248
>XP_005245315
          Length = 1607

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    VATFILGI 8
            VAT++LGI
Sbjct: 1159 VATYVLGI 1166
>XP_006711447
          Length = 1634

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    VATFILGI 8
            VAT++LGI
Sbjct: 1186 VATYVLGI 1193
>XP_005245314
          Length = 1634

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    VATFILGI 8
            VAT++LGI
Sbjct: 1186 VATYVLGI 1193
>XP_006710753
          Length = 1015

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VATFILGI 8
           VAT++LGI
Sbjct: 855 VATYVLGI 862
>XP_005263530
          Length = 1043

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VATFILGI 8
           VAT++LGI
Sbjct: 883 VATYVLGI 890
>XP_006710752
          Length = 1044

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VATFILGI 8
           VAT++LGI
Sbjct: 884 VATYVLGI 891
>XP_006710751
          Length = 1044

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VATFILGI 8
           VAT++LGI
Sbjct: 884 VATYVLGI 891
>XP_006710750
          Length = 1044

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VATFILGI 8
           VAT++LGI
Sbjct: 884 VATYVLGI 891
>XP_006710749
          Length = 1044

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VATFILGI 8
           VAT++LGI
Sbjct: 884 VATYVLGI 891
>NP_002637
          Length = 1634

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    VATFILGI 8
            VAT++LGI
Sbjct: 1186 VATYVLGI 1193
>NP_001275701
          Length = 1486

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VATFILGI 8
            V TFILG+
Sbjct: 1065 VVTFILGV 1072
>NP_004561
          Length = 1445

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VATFILGI 8
            V TFILG+
Sbjct: 1024 VVTFILGV 1031
>NP_001275703
          Length = 1264

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VATFILGI 8
           V TFILG+
Sbjct: 843 VVTFILGV 850
>XP_005253450
          Length = 1486

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VATFILGI 8
            V TFILG+
Sbjct: 1065 VVTFILGV 1072
>XP_006719151
          Length = 1486

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VATFILGI 8
            V TFILG+
Sbjct: 1065 VVTFILGV 1072
>NP_116207
          Length = 335

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VATFILGI 8
          VAT+ LGI
Sbjct: 44 VATYFLGI 51
>NP_005674
          Length = 319

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  VATFILGI 8
          + TF+LG+
Sbjct: 28 IPTFVLGL 35
>NP_001161957
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VATFILGI 8
           +AT I+GI
Sbjct: 330 IATMIMGI 337
>NP_001161954
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VATFILGI 8
           +AT I+GI
Sbjct: 330 IATMIMGI 337
>NP_001161951
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VATFILGI 8
           +AT I+GI
Sbjct: 330 IATMIMGI 337
>NP_001161952
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VATFILGI 8
           +AT I+GI
Sbjct: 330 IATMIMGI 337
>NP_073749
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VATFILGI 8
           +AT I+GI
Sbjct: 330 IATMIMGI 337
>NP_001161950
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VATFILGI 8
           +AT I+GI
Sbjct: 330 IATMIMGI 337
>NP_002638
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VATFILGI 8
           V T+ILG+
Sbjct: 734 VITYILGV 741
>NP_001107604
          Length = 2694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VATFILGIR 9
           VATFIL ++
Sbjct: 930 VATFILIVK 938
>NP_036537
          Length = 284

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VATFILG 7
          +ATF+LG
Sbjct: 18 LATFLLG 24
>XP_006721734
          Length = 176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VATFILGI 8
           + TF+LGI
Sbjct: 132 LGTFLLGI 139
>XP_005247009
          Length = 319

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  VATFILGI 8
          + TF+LG+
Sbjct: 28 IPTFVLGL 35
>XP_006712765
          Length = 2679

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VATFILGIR 9
           VATFIL ++
Sbjct: 902 VATFILIVK 910
>XP_006712764
          Length = 2697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VATFILGIR 9
           VATFIL ++
Sbjct: 959 VATFILIVK 967
>XP_005246844
          Length = 2707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VATFILGIR 9
           VATFIL ++
Sbjct: 930 VATFILIVK 938
>XP_006712763
          Length = 2716

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VATFILGIR 9
           VATFIL ++
Sbjct: 959 VATFILIVK 967
>XP_006712762
          Length = 2723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VATFILGIR 9
           VATFIL ++
Sbjct: 959 VATFILIVK 967
>XP_006712761
          Length = 2736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VATFILGIR 9
           VATFIL ++
Sbjct: 959 VATFILIVK 967
>XP_005263494
          Length = 284

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VATFILG 7
          +ATF+LG
Sbjct: 18 LATFLLG 24
>NP_001153879
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VATFILGI 8
           + TF+LGI
Sbjct: 156 LGTFLLGI 163
>NP_612472
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VATFILGI 8
           + TF+LGI
Sbjct: 203 LGTFLLGI 210
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.347    0.161    0.449 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 386,835
Number of extensions: 473
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

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