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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              18    1482
XP_006718908                                                           18    1482
XP_005271621                                                           18    1482
XP_006718907                                                           18    1482
XP_006718906                                                           18    1482
XP_005271619                                                           18    1482
XP_005271618                                                           18    1482
NP_740752                                                              16    7355
NP_002240                                                              16    7355
NP_001191016                                                           16    7355
NP_002239                                                              16    7355
NP_001265133                                                           16    7355
NP_067627                                                              16    7355
NP_740721                                                              16    7355
XP_005259964                                                           16    7355
XP_005259963                                                           16    7355
XP_005259962                                                           16    7355
XP_006714676                                                           16    7355

>NP_000042
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VARRIRITK 9
            VARR RITK
Sbjct: 2577 VARRSRITK 2585



>XP_006718908
          Length = 1708

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VARRIRITK 9
            VARR RITK
Sbjct: 1229 VARRSRITK 1237



>XP_005271621
          Length = 2708

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VARRIRITK 9
            VARR RITK
Sbjct: 2229 VARRSRITK 2237



>XP_006718907
          Length = 3050

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VARRIRITK 9
            VARR RITK
Sbjct: 2571 VARRSRITK 2579



>XP_006718906
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VARRIRITK 9
            VARR RITK
Sbjct: 2577 VARRSRITK 2585



>XP_005271619
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VARRIRITK 9
            VARR RITK
Sbjct: 2577 VARRSRITK 2585



>XP_005271618
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VARRIRITK 9
            VARR RITK
Sbjct: 2577 VARRSRITK 2585



>NP_740752
          Length = 426

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VARRIRITK 9
           VAR++ +TK
Sbjct: 237 VARKLELTK 245



>NP_002240
          Length = 731

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VARRIRITK 9
           VAR++ +TK
Sbjct: 542 VARKLELTK 550



>NP_001191016
          Length = 746

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VARRIRITK 9
           VAR++ +TK
Sbjct: 557 VARKLELTK 565



>NP_002239
          Length = 543

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VARRIRITK 9
           VAR++ +TK
Sbjct: 365 VARKLELTK 373



>NP_001265133
          Length = 231

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VARRIRITK 9
          VAR++ +TK
Sbjct: 45 VARKLELTK 53



>NP_067627
          Length = 579

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VARRIRITK 9
           VAR++ +TK
Sbjct: 393 VARKLELTK 401



>NP_740721
          Length = 231

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VARRIRITK 9
          VAR++ +TK
Sbjct: 45 VARKLELTK 53



>XP_005259964
          Length = 623

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VARRIRITK 9
           VAR++ +TK
Sbjct: 448 VARKLELTK 456



>XP_005259963
          Length = 626

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VARRIRITK 9
           VAR++ +TK
Sbjct: 448 VARKLELTK 456



>XP_005259962
          Length = 629

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VARRIRITK 9
           VAR++ +TK
Sbjct: 451 VARKLELTK 459



>XP_006714676
          Length = 850

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VARRIRITK 9
           VAR++ +TK
Sbjct: 661 VARKLELTK 669



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.344    0.147    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 284,636
Number of extensions: 314
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)