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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              18    1135
XP_005267290                                                           18    1135
NP_078963                                                              17    2528
NP_001186131                                                           17    2528
NP_001186130                                                           17    2528
XP_005247836                                                           17    2528
XP_006713811                                                           17    2528
XP_006713810                                                           17    2528
XP_005247834                                                           17    2528
NP_071760                                                              16    5631
NP_055640                                                              16    7355
NP_001116856                                                           15    9605
NP_001116855                                                           15    9605
NP_060215                                                              15    9605
NP_001116857                                                           15    9605
NP_056306                                                              15    9605
NP_116259                                                              15    9605
NP_055523                                                              15    9605
NP_065145                                                              15    9605
NP_659436                                                              15    9605
XP_005272677                                                           15    9605
XP_005272676                                                           15    9605
XP_005272675                                                           15    9605
XP_005272674                                                           15    9605
XP_006724599                                                           15    9605
XP_005272673                                                           15    9605
XP_006722338                                                           15    9605
XP_006719769                                                           15    9605
XP_006715515                                                           15    9605
XP_006715514                                                           15    9605
XP_006715513                                                           15    9605
XP_005266974                                                           15    9605
XP_005266973                                                           15    9605
XP_005266972                                                           15    9605
XP_005266971                                                           15    9605
XP_005266970                                                           15    9605
XP_005266969                                                           15    9605

>NP_005091
          Length = 1782

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  VAEQNELSL 9
          VAEQ+ELSL
Sbjct: 68 VAEQDELSL 76



>XP_005267290
          Length = 1782

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  VAEQNELSL 9
          VAEQ+ELSL
Sbjct: 68 VAEQDELSL 76



>NP_078963
          Length = 800

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VAEQNELSL 9
           + +QNELSL
Sbjct: 681 ITDQNELSL 689



>NP_001186131
          Length = 771

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VAEQNELSL 9
           + +QNELSL
Sbjct: 652 ITDQNELSL 660



>NP_001186130
          Length = 839

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VAEQNELSL 9
           + +QNELSL
Sbjct: 720 ITDQNELSL 728



>XP_005247836
          Length = 627

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VAEQNELSL 9
           + +QNELSL
Sbjct: 508 ITDQNELSL 516



>XP_006713811
          Length = 800

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VAEQNELSL 9
           + +QNELSL
Sbjct: 681 ITDQNELSL 689



>XP_006713810
          Length = 838

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VAEQNELSL 9
           + +QNELSL
Sbjct: 719 ITDQNELSL 727



>XP_005247834
          Length = 839

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VAEQNELSL 9
           + +QNELSL
Sbjct: 720 ITDQNELSL 728



>NP_071760
          Length = 554

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VAEQNELS 8
           +AEQNE S
Sbjct: 473 IAEQNESS 480



>NP_055640
          Length = 2271

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EQNELSL 9
            EQN+LSL
Sbjct: 1552 EQNKLSL 1558



>NP_001116856
          Length = 1703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    VAEQNE 6
            +AEQNE
Sbjct: 1053 IAEQNE 1058



>NP_001116855
          Length = 1721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    VAEQNE 6
            +AEQNE
Sbjct: 1071 IAEQNE 1076



>NP_060215
          Length = 1721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    VAEQNE 6
            +AEQNE
Sbjct: 1071 IAEQNE 1076



>NP_001116857
          Length = 1755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    VAEQNE 6
            +AEQNE
Sbjct: 1071 IAEQNE 1076



>NP_056306
          Length = 805

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EQNELSL 9
           EQN LSL
Sbjct: 462 EQNSLSL 468



>NP_116259
          Length = 805

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EQNELSL 9
           EQN LSL
Sbjct: 462 EQNSLSL 468



>NP_055523
          Length = 2209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VAEQNELSL 9
            +AE NE++L
Sbjct: 1804 IAEVNEINL 1812



>NP_065145
          Length = 199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   AEQNELS 8
           AEQ+ELS
Sbjct: 183 AEQDELS 189



>NP_659436
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AEQNELSL 9
           AEQ +LSL
Sbjct: 329 AEQEQLSL 336



>XP_005272677
          Length = 1703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    VAEQNE 6
            +AEQNE
Sbjct: 1053 IAEQNE 1058



>XP_005272676
          Length = 1737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    VAEQNE 6
            +AEQNE
Sbjct: 1053 IAEQNE 1058



>XP_005272675
          Length = 1755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    VAEQNE 6
            +AEQNE
Sbjct: 1071 IAEQNE 1076



>XP_005272674
          Length = 1755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    VAEQNE 6
            +AEQNE
Sbjct: 1071 IAEQNE 1076



>XP_006724599
          Length = 1755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    VAEQNE 6
            +AEQNE
Sbjct: 1071 IAEQNE 1076



>XP_005272673
          Length = 1755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    VAEQNE 6
            +AEQNE
Sbjct: 1071 IAEQNE 1076



>XP_006722338
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AEQNELSL 9
           AEQ +LSL
Sbjct: 329 AEQEQLSL 336



>XP_006719769
          Length = 2209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VAEQNELSL 9
            +AE NE++L
Sbjct: 1804 IAEVNEINL 1812



>XP_006715515
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EQNELSL 9
           EQN LSL
Sbjct: 367 EQNSLSL 373



>XP_006715514
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EQNELSL 9
           EQN LSL
Sbjct: 367 EQNSLSL 373



>XP_006715513
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EQNELSL 9
           EQN LSL
Sbjct: 367 EQNSLSL 373



>XP_005266974
          Length = 814

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EQNELSL 9
           EQN LSL
Sbjct: 462 EQNSLSL 468



>XP_005266973
          Length = 814

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EQNELSL 9
           EQN LSL
Sbjct: 462 EQNSLSL 468



>XP_005266972
          Length = 814

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EQNELSL 9
           EQN LSL
Sbjct: 462 EQNSLSL 468



>XP_005266971
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EQNELSL 9
           EQN LSL
Sbjct: 507 EQNSLSL 513



>XP_005266970
          Length = 868

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EQNELSL 9
           EQN LSL
Sbjct: 525 EQNSLSL 531



>XP_005266969
          Length = 877

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EQNELSL 9
           EQN LSL
Sbjct: 525 EQNSLSL 531



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.295    0.115    0.256 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 406,034
Number of extensions: 424
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)