Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005912                                                              20     299
XP_005248577                                                           20     299
XP_005248576                                                           20     299
NP_005206                                                              18    1935
XP_005258261                                                           18    1935
NP_065754                                                              17    2528
NP_004611                                                              17    3301
NP_665802                                                              17    3301
NP_055454                                                              17    4312
NP_001007528                                                           17    4312
NP_001495                                                              16    7355
NP_001136269                                                           16    7355
NP_852091                                                              16    7355
NP_789789                                                              16    7355
NP_000706                                                              16    7355
XP_005262314                                                           16    7355
XP_005262313                                                           16    7355
XP_006724622                                                           16    7355
XP_005272727                                                           16    7355
XP_005273308                                                           16    7355
XP_005273309                                                           16    7355
NP_001243092                                                           15    9605
NP_001243095                                                           15    9605
NP_001157                                                              15    9605
NP_006197                                                              15    9605
NP_001069                                                              15    9605
NP_001186763                                                           15    9605
NP_542413                                                              15    9605
NP_001618                                                              15    9605
NP_008995                                                              15    9605
NP_001019831                                                           15    9605
NP_001191433                                                           15    9605
NP_821077                                                              15    9605
NP_001191435                                                           15    9605
NP_001191434                                                           15    9605
NP_690874                                                              15    9605
NP_002301                                                              15    9605
NP_001121143                                                           15    9605
NP_001230212                                                           15    9605
NP_001230210                                                           15    9605
NP_001230209                                                           15    9605
NP_001156                                                              15    9605
NP_892007                                                              15    9605
NP_056273                                                              15    9605
NP_055616                                                              15    9605
NP_001276077                                                           15    9605
NP_001276078                                                           15    9605
NP_061138                                                              15    9605
XP_005254945                                                           15    9605
XP_005254944                                                           15    9605
XP_005266328                                                           15    9605
XP_006714104                                                           15    9605
XP_005265800                                                           15    9605
XP_006714103                                                           15    9605
XP_006714102                                                           15    9605
XP_006713877                                                           15    9605
XP_006713876                                                           15    9605
XP_006713875                                                           15    9605
XP_006713874                                                           15    9605
XP_006713873                                                           15    9605
XP_005273329                                                           15    9605
>NP_005912
          Length = 1512

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VADTILVKC 9
           V DTILVKC
Sbjct: 683 VVDTILVKC 691
>XP_005248577
          Length = 1349

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VADTILVKC 9
           V DTILVKC
Sbjct: 520 VVDTILVKC 528
>XP_005248576
          Length = 1375

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VADTILVKC 9
           V DTILVKC
Sbjct: 546 VVDTILVKC 554
>NP_005206
          Length = 1447

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VADTILVKC 9
           + DT+L+KC
Sbjct: 153 MGDTVLLKC 161
>XP_005258261
          Length = 1447

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VADTILVKC 9
           + DT+L+KC
Sbjct: 153 MGDTVLLKC 161
>NP_065754
          Length = 493

 Score = 17.3 bits (33), Expect =  2528
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VADTILVKC 9
           + DT+++KC
Sbjct: 282 LGDTLIIKC 290
>NP_004611
          Length = 522

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DTILVKC 9
           DT+LV+C
Sbjct: 491 DTLLVRC 497
>NP_665802
          Length = 522

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DTILVKC 9
           DT+LV+C
Sbjct: 491 DTLLVRC 497
>NP_055454
          Length = 1564

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VADTILVKC 9
            VA T+L KC
Sbjct: 1106 VAKTLLFKC 1114
>NP_001007528
          Length = 695

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   DTILVKC 9
           DTIL KC
Sbjct: 269 DTILKKC 275
>NP_001495
          Length = 368

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VADTILV 7
           VADT+LV
Sbjct: 97  VADTLLV 103
>NP_001136269
          Length = 415

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VADTILV 7
           VADT+LV
Sbjct: 144 VADTLLV 150
>NP_852091
          Length = 941

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VADTILVKC 9
           VAD  L+KC
Sbjct: 285 VADRKLLKC 293
>NP_789789
          Length = 433

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DTILVKC 9
           D+ILV+C
Sbjct: 383 DSILVQC 389
>NP_000706
          Length = 597

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   DTILVKC 9
           DTI+ KC
Sbjct: 261 DTIVFKC 267
>XP_005262314
          Length = 278

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VADTILV 7
           VADT+LV
Sbjct: 107 VADTLLV 113
>XP_005262313
          Length = 378

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VADTILV 7
           VADT+LV
Sbjct: 107 VADTLLV 113
>XP_006724622
          Length = 349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DTILVKC 9
           D+ILV+C
Sbjct: 299 DSILVQC 305
>XP_005272727
          Length = 375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DTILVKC 9
           D+ILV+C
Sbjct: 325 DSILVQC 331
>XP_005273308
          Length = 597

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   DTILVKC 9
           DTI+ KC
Sbjct: 261 DTIVFKC 267
>XP_005273309
          Length = 597

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   DTILVKC 9
           DTI+ KC
Sbjct: 261 DTIVFKC 267
>NP_001243092
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DTILVK 8
           DTILVK
Sbjct: 511 DTILVK 516
>NP_001243095
          Length = 569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DTILVK 8
           DTILVK
Sbjct: 462 DTILVK 467
>NP_001157
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DTILVK 8
           DTILVK
Sbjct: 511 DTILVK 516
>NP_006197
          Length = 1089

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VADTILVKC 9
           V +TI V+C
Sbjct: 493 VEETIAVRC 501
>NP_001069
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/7 (42%), Positives = 6/7 (85%)

Query: 3   DTILVKC 9
           DT+++ C
Sbjct: 617 DTVIISC 623
>NP_001186763
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/7 (42%), Positives = 6/7 (85%)

Query: 3   DTILVKC 9
           DT+++ C
Sbjct: 555 DTVIISC 561
>NP_542413
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/7 (42%), Positives = 6/7 (85%)

Query: 3   DTILVKC 9
           DT+++ C
Sbjct: 525 DTVIISC 531
>NP_001618
          Length = 583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3  DTILVKC 9
          DTI++ C
Sbjct: 37 DTIIIPC 43
>NP_008995
          Length = 1289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   VADTILVKC 9
           + DT++++C
Sbjct: 787 LGDTVILQC 795
>NP_001019831
          Length = 2986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1    VADTILVKC 9
            + DT++++C
Sbjct: 2484 LGDTVILQC 2492
>NP_001191433
          Length = 1164

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   VADTILVKC 9
           VAD +  KC
Sbjct: 539 VADAVASKC 547
>NP_821077
          Length = 1220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   VADTILVKC 9
           VAD +  KC
Sbjct: 539 VADAVASKC 547
>NP_001191435
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   VADTILVKC 9
           VAD +  KC
Sbjct: 403 VADAVASKC 411
>NP_001191434
          Length = 1100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   VADTILVKC 9
           VAD +  KC
Sbjct: 403 VADAVASKC 411
>NP_690874
          Length = 1164

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   VADTILVKC 9
           VAD +  KC
Sbjct: 539 VADAVASKC 547
>NP_002301
          Length = 1097

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ADTILVK 8
           AD+ILVK
Sbjct: 737 ADSILVK 743
>NP_001121143
          Length = 1097

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ADTILVK 8
           AD+ILVK
Sbjct: 737 ADSILVK 743
>NP_001230212
          Length = 133

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3  DTILVKC 9
          DTI++ C
Sbjct: 37 DTIIIPC 43
>NP_001230210
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3  DTILVKC 9
          DTI++ C
Sbjct: 37 DTIIIPC 43
>NP_001230209
          Length = 570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3  DTILVKC 9
          DTI++ C
Sbjct: 37 DTIIIPC 43
>NP_001156
          Length = 604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DTILVK 8
           DTILVK
Sbjct: 497 DTILVK 502
>NP_892007
          Length = 604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DTILVK 8
           DTILVK
Sbjct: 497 DTILVK 502
>NP_056273
          Length = 549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4  TILVKC 9
          TI++KC
Sbjct: 68 TIIIKC 73
>NP_055616
          Length = 2137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VADTILVKC 9
            VADT+ V C
Sbjct: 2106 VADTLGVVC 2114
>NP_001276077
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   VADTILVKC 9
           V DT  +KC
Sbjct: 224 VDDTFRIKC 232
>NP_001276078
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   VADTILVKC 9
           V DT  +KC
Sbjct: 160 VDDTFRIKC 168
>NP_061138
          Length = 617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   VADTILVKC 9
           V DT  +KC
Sbjct: 251 VDDTFRIKC 259
>XP_005254945
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   VADTILVKC 9
           V DT  +KC
Sbjct: 251 VDDTFRIKC 259
>XP_005254944
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   VADTILVKC 9
           V DT  +KC
Sbjct: 160 VDDTFRIKC 168
>XP_005266328
          Length = 919

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   VADTILVKC 9
           VAD +  KC
Sbjct: 294 VADAVASKC 302
>XP_006714104
          Length = 832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VADTILVKC 9
           V +TI V+C
Sbjct: 518 VEETIAVRC 526
>XP_005265800
          Length = 1089

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VADTILVKC 9
           V +TI V+C
Sbjct: 493 VEETIAVRC 501
>XP_006714103
          Length = 1111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VADTILVKC 9
           V +TI V+C
Sbjct: 515 VEETIAVRC 523
>XP_006714102
          Length = 1114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VADTILVKC 9
           V +TI V+C
Sbjct: 518 VEETIAVRC 526
>XP_006713877
          Length = 2956

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1    VADTILVKC 9
            + DT++++C
Sbjct: 2454 LGDTVILQC 2462
>XP_006713876
          Length = 2966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1    VADTILVKC 9
            + DT++++C
Sbjct: 2464 LGDTVILQC 2472
>XP_006713875
          Length = 2975

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1    VADTILVKC 9
            + DT++++C
Sbjct: 2473 LGDTVILQC 2481
>XP_006713874
          Length = 2979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1    VADTILVKC 9
            + DT++++C
Sbjct: 2477 LGDTVILQC 2485
>XP_006713873
          Length = 2988

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1    VADTILVKC 9
            + DT++++C
Sbjct: 2486 LGDTVILQC 2494
>XP_005273329
          Length = 1934

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VADTILVKC 9
            VADT+ V C
Sbjct: 1903 VADTLGVVC 1911
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.333    0.141    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 427,493
Number of extensions: 760
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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