Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              21     229
NP_001035957                                                           21     229
XP_006721990                                                           21     229
XP_006721989                                                           21     229
XP_005258041                                                           21     229
XP_006721988                                                           21     229
XP_006721987                                                           21     229
XP_006721986                                                           21     229
XP_005258040                                                           21     229
XP_006721985                                                           21     229
NP_078966                                                              17    3301
XP_006723004                                                           17    3301
NP_004144                                                              17    4312
NP_001177748                                                           17    4312
NP_001177747                                                           17    4312
NP_001136245                                                           16    5631
NP_001136239                                                           16    5631
NP_001136236                                                           16    5631
NP_001136238                                                           16    5631
NP_001136240                                                           16    5631
NP_001136235                                                           16    5631
NP_001136237                                                           16    5631
NP_149045                                                              16    5631
NP_055073                                                              16    5631
NP_031397                                                              16    5631
XP_006723744                                                           16    5631
XP_005260304                                                           16    5631
XP_005272271                                                           16    5631
XP_006717354                                                           16    5631
NP_036336                                                              16    5631
NP_064594                                                              16    7355
NP_001092108                                                           16    7355
NP_116267                                                              16    7355
XP_006723512                                                           16    7355
XP_005259417                                                           16    7355
XP_005259416                                                           16    7355
XP_005259415                                                           16    7355
XP_005259414                                                           16    7355
NP_001071161                                                           15    9605
NP_001122391                                                           15    9605
NP_002367                                                              15    9605
NP_001122392                                                           15    9605
NP_001122390                                                           15    9605
NP_001122393                                                           15    9605
NP_001269727                                                           15    9605
NP_001269729                                                           15    9605
NP_001135906                                                           15    9605
NP_056222                                                              15    9605
NP_056176                                                              15    9605
NP_036347                                                              15    9605
NP_002941                                                              15    9605
NP_001161076                                                           15    9605
NP_065116                                                              15    9605
NP_775871                                                              15    9605
XP_006720210                                                           15    9605
XP_005267700                                                           15    9605
XP_005267699                                                           15    9605
XP_005267698                                                           15    9605
XP_006720209                                                           15    9605
XP_006718026                                                           15    9605
XP_005270202                                                           15    9605
XP_006718025                                                           15    9605
XP_005270201                                                           15    9605
XP_005263690                                                           15    9605
XP_005263689                                                           15    9605
XP_005263688                                                           15    9605
XP_005263681                                                           15    9605
XP_005263680                                                           15    9605
XP_006712453                                                           15    9605
XP_005263679                                                           15    9605
XP_006712452                                                           15    9605
NP_001139669                                                           15    9605
>NP_000258
          Length = 2818

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TYPTVSQTS 9
            TYPTV QTS
Sbjct: 2486 TYPTVGQTS 2494
>NP_001035957
          Length = 2839

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TYPTVSQTS 9
            TYPTV QTS
Sbjct: 2507 TYPTVGQTS 2515
>XP_006721990
          Length = 2823

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TYPTVSQTS 9
            TYPTV QTS
Sbjct: 2517 TYPTVGQTS 2525
>XP_006721989
          Length = 2823

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TYPTVSQTS 9
            TYPTV QTS
Sbjct: 2517 TYPTVGQTS 2525
>XP_005258041
          Length = 2836

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TYPTVSQTS 9
            TYPTV QTS
Sbjct: 2486 TYPTVGQTS 2494
>XP_006721988
          Length = 2846

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TYPTVSQTS 9
            TYPTV QTS
Sbjct: 2496 TYPTVGQTS 2504
>XP_006721987
          Length = 2849

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TYPTVSQTS 9
            TYPTV QTS
Sbjct: 2517 TYPTVGQTS 2525
>XP_006721986
          Length = 2854

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TYPTVSQTS 9
            TYPTV QTS
Sbjct: 2504 TYPTVGQTS 2512
>XP_005258040
          Length = 2857

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TYPTVSQTS 9
            TYPTV QTS
Sbjct: 2507 TYPTVGQTS 2515
>XP_006721985
          Length = 2867

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TYPTVSQTS 9
            TYPTV QTS
Sbjct: 2517 TYPTVGQTS 2525
>NP_078966
          Length = 14507

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1     TYPTVSQT 8
             T+PT+S+T
Sbjct: 11560 TFPTLSET 11567

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     TYPTVSQTS 9
             T PTVS+T+
Sbjct: 10606 TIPTVSKTT 10614
>XP_006723004
          Length = 6443

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    TYPTVSQT 8
            T+PT+S+T
Sbjct: 3474 TFPTLSET 3481

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TYPTVSQTS 9
            T PTVS+T+
Sbjct: 2520 TIPTVSKTT 2528
>NP_004144
          Length = 861

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   YPTVSQT 8
           YPT+S+T
Sbjct: 813 YPTMSET 819
>NP_001177748
          Length = 856

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   YPTVSQT 8
           YPT+S+T
Sbjct: 808 YPTMSET 814
>NP_001177747
          Length = 861

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   YPTVSQT 8
           YPT+S+T
Sbjct: 813 YPTMSET 819
>NP_001136245
          Length = 1932

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TYPTVSQT 8
            T PTVS+T
Sbjct: 1650 TLPTVSRT 1657
>NP_001136239
          Length = 1915

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TYPTVSQT 8
            T PTVS+T
Sbjct: 1633 TLPTVSRT 1640
>NP_001136236
          Length = 1957

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TYPTVSQT 8
            T PTVS+T
Sbjct: 1675 TLPTVSRT 1682
>NP_001136238
          Length = 1952

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TYPTVSQT 8
            T PTVS+T
Sbjct: 1670 TLPTVSRT 1677
>NP_001136240
          Length = 1935

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TYPTVSQT 8
            T PTVS+T
Sbjct: 1653 TLPTVSRT 1660
>NP_001136235
          Length = 1962

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TYPTVSQT 8
            T PTVS+T
Sbjct: 1680 TLPTVSRT 1687
>NP_001136237
          Length = 1886

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TYPTVSQT 8
            T PTVS+T
Sbjct: 1604 TLPTVSRT 1611
>NP_149045
          Length = 1955

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TYPTVSQT 8
            T PTVS+T
Sbjct: 1673 TLPTVSRT 1680
>NP_055073
          Length = 1530

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PTVSQTS 9
           P+VSQTS
Sbjct: 523 PSVSQTS 529
>NP_031397
          Length = 726

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   PTVSQT 8
           PTVSQT
Sbjct: 188 PTVSQT 193
>XP_006723744
          Length = 847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PTVSQTS 9
           P+VSQTS
Sbjct: 523 PSVSQTS 529
>XP_005260304
          Length = 1530

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PTVSQTS 9
           P+VSQTS
Sbjct: 523 PSVSQTS 529
>XP_005272271
          Length = 725

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   PTVSQT 8
           PTVSQT
Sbjct: 188 PTVSQT 193
>XP_006717354
          Length = 726

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   PTVSQT 8
           PTVSQT
Sbjct: 188 PTVSQT 193
>NP_036336
          Length = 822

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   PTVSQT 8
           PTVSQT
Sbjct: 139 PTVSQT 144
>NP_064594
          Length = 340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YPTVSQT 8
           YP V+QT
Sbjct: 333 YPVVTQT 339
>NP_001092108
          Length = 708

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   YPTVSQT 8
           +P+VSQT
Sbjct: 504 FPSVSQT 510
>NP_116267
          Length = 266

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YPTVS  S
Sbjct: 149 YPTVSTIS 156
>XP_006723512
          Length = 163

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  YPTVSQTS 9
          YPTVS  S
Sbjct: 46 YPTVSTIS 53
>XP_005259417
          Length = 163

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  YPTVSQTS 9
          YPTVS  S
Sbjct: 46 YPTVSTIS 53
>XP_005259416
          Length = 169

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  YPTVSQTS 9
          YPTVS  S
Sbjct: 52 YPTVSTIS 59
>XP_005259415
          Length = 238

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YPTVS  S
Sbjct: 121 YPTVSTIS 128
>XP_005259414
          Length = 238

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YPTVS  S
Sbjct: 121 YPTVSTIS 128
>NP_001071161
          Length = 205

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  PTVSQTS 9
          PT++QTS
Sbjct: 26 PTMTQTS 32
>NP_001122391
          Length = 744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YP  SQTS
Sbjct: 432 YPKRSQTS 439
>NP_002367
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YP  SQTS
Sbjct: 432 YPKRSQTS 439
>NP_001122392
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YP  SQTS
Sbjct: 416 YPKRSQTS 423
>NP_001122390
          Length = 753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YP  SQTS
Sbjct: 432 YPKRSQTS 439
>NP_001122393
          Length = 659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YP  SQTS
Sbjct: 353 YPKRSQTS 360
>NP_001269727
          Length = 1100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YPTVS  S
Sbjct: 444 YPTVSTHS 451
>NP_001269729
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YPTVS  S
Sbjct: 388 YPTVSTHS 395
>NP_001135906
          Length = 863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YPTVSQT 8
           YP VSQ+
Sbjct: 225 YPNVSQS 231
>NP_056222
          Length = 271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  PTVSQTS 9
          PTV QTS
Sbjct: 23 PTVVQTS 29
>NP_056176
          Length = 1099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YPTVS  S
Sbjct: 444 YPTVSTHS 451
>NP_036347
          Length = 916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YPTVSQT 8
           YP VSQ+
Sbjct: 225 YPNVSQS 231
>NP_002941
          Length = 607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YPTVSQT 8
           YPT +QT
Sbjct: 166 YPTKTQT 172
>NP_001161076
          Length = 642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   TYPTVSQT 8
           ++PT+S T
Sbjct: 423 SFPTISST 430
>NP_065116
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   TYPTVSQT 8
           ++PT+S T
Sbjct: 423 SFPTISST 430
>NP_775871
          Length = 8384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    PTVSQTS 9
            PTV+QT+
Sbjct: 3171 PTVTQTT 3177
>XP_006720210
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YP  SQTS
Sbjct: 301 YPKRSQTS 308
>XP_005267700
          Length = 643

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YP  SQTS
Sbjct: 432 YPKRSQTS 439
>XP_005267699
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YP  SQTS
Sbjct: 416 YPKRSQTS 423
>XP_005267698
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YP  SQTS
Sbjct: 432 YPKRSQTS 439
>XP_006720209
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YP  SQTS
Sbjct: 418 YPKRSQTS 425
>XP_006718026
          Length = 552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   TYPTVSQT 8
           ++PT+S T
Sbjct: 309 SFPTISST 316
>XP_005270202
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   TYPTVSQT 8
           ++PT+S T
Sbjct: 375 SFPTISST 382
>XP_006718025
          Length = 645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   TYPTVSQT 8
           ++PT+S T
Sbjct: 423 SFPTISST 430
>XP_005270201
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   TYPTVSQT 8
           ++PT+S T
Sbjct: 419 SFPTISST 426
>XP_005263690
          Length = 591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YPTVS  S
Sbjct: 444 YPTVSTHS 451
>XP_005263689
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YPTVS  S
Sbjct: 231 YPTVSTHS 238
>XP_005263688
          Length = 948

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YPTVS  S
Sbjct: 444 YPTVSTHS 451
>XP_005263681
          Length = 1056

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YPTVS  S
Sbjct: 400 YPTVSTHS 407
>XP_005263680
          Length = 1056

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YPTVS  S
Sbjct: 400 YPTVSTHS 407
>XP_006712453
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YPTVS  S
Sbjct: 428 YPTVSTHS 435
>XP_005263679
          Length = 1086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YPTVS  S
Sbjct: 430 YPTVSTHS 437
>XP_006712452
          Length = 1100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YPTVSQTS 9
           YPTVS  S
Sbjct: 444 YPTVSTHS 451
>NP_001139669
          Length = 7081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   TYPTVSQ 7
           TY T+SQ
Sbjct: 845 TYTTISQ 851
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.295    0.104    0.276 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 526,865
Number of extensions: 929
Number of successful extensions: 74
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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